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Items: 12


Reconstruction of complex single-cell trajectories using CellRouter.

Lummertz da Rocha E, Rowe RG, Lundin V, Malleshaiah M, Jha DK, Rambo CR, Li H, North TE, Collins JJ, Daley GQ.

Nat Commun. 2018 Mar 1;9(1):892. doi: 10.1038/s41467-018-03214-y.


Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.

Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17.


Protein-Fragment Complementation Assays for Large-Scale Analysis, Functional Dissection, and Spatiotemporal Dynamic Studies of Protein-Protein Interactions in Living Cells.

Michnick SW, Landry CR, Levy ED, Diss G, Ear PH, Kowarzyk J, Malleshaiah MK, Messier V, Tchekanda E.

Cold Spring Harb Protoc. 2016 Nov 1;2016(11). doi: 10.1101/pdb.top083543.


Real-Time Protein-Fragment Complementation Assays for Studying Temporal, Spatial, and Spatiotemporal Dynamics of Protein-Protein Interactions in Living Cells.

Malleshaiah M, Tchekanda E, Michnick SW.

Cold Spring Harb Protoc. 2016 Nov 1;2016(11). doi: 10.1101/pdb.prot090068.


Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation.

Malleshaiah M, Padi M, Rué P, Quackenbush J, Martinez-Arias A, Gunawardena J.

Cell Rep. 2016 Feb 9;14(5):1181-1194. doi: 10.1016/j.celrep.2015.12.101. Epub 2016 Jan 28.


Cybernetics, Redux: An Outside-In Strategy for Unraveling Cellular Function.

Malleshaiah M, Gunawardena J.

Dev Cell. 2016 Jan 11;36(1):2-4. doi: 10.1016/j.devcel.2015.12.025.


In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs.

Röck R, Bachmann V, Bhang HE, Malleshaiah M, Raffeiner P, Mayrhofer JE, Tschaikner PM, Bister K, Aanstad P, Pomper MG, Michnick SW, Stefan E.

Sci Rep. 2015 Jun 23;5:11133. doi: 10.1038/srep11133.


PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades.

Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW.

Nat Commun. 2011 Dec 20;2:598. doi: 10.1038/ncomms1605.


Protein-fragment complementation assays for large-scale analysis, functional dissection and dynamic studies of protein-protein interactions in living cells.

Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V.

Methods Mol Biol. 2011;756:395-425. doi: 10.1007/978-1-61779-160-4_25.


A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells.

Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V.

Methods Enzymol. 2010;470:335-68. doi: 10.1016/S0076-6879(10)70014-8. Epub 2010 Mar 1.


The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.

Malleshaiah MK, Shahrezaei V, Swain PS, Michnick SW.

Nature. 2010 May 6;465(7294):101-5. doi: 10.1038/nature08946. Epub 2010 Apr 18.


A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF.

Manderson EN, Malleshaiah M, Michnick SW.

PLoS One. 2008 Jan 30;3(1):e1500. doi: 10.1371/journal.pone.0001500.

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