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Items: 1 to 20 of 177

1.

THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage.

Santiago-Sim T, Fang X, Hennessy ML, Nalbach SV, DePalma SR, Lee MS, Greenway SC, McDonough B, Hergenroeder GW, Patek KJ, Colosimo SM, Qualmann KJ, Hagan JP, Milewicz DM, MacRae CA, Dymecki SM, Seidman CE, Seidman JG, Kim DH.

Stroke. 2016 Dec;47(12):3005-3013.

PMID:
27895300
2.

A countermeasure development pipeline.

MacRae CA, Boss G, Brenner M, Gerszten RE, Mahon S, Peterson RT.

Ann N Y Acad Sci. 2016 Aug;1378(1):58-67. doi: 10.1111/nyas.13224.

PMID:
27737495
3.

De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype.

Shashi V, Pena LD, Kim K, Burton B, Hempel M, Schoch K, Walkiewicz M, McLaughlin HM, Cho M, Stong N, Hickey SE, Shuss CM; Undiagnosed Diseases Network., Freemark MS, Bellet JS, Keels MA, Bonner MJ, El-Dairi M, Butler M, Kranz PG, Stumpel CT, Klinkenberg S, Oberndorff K, Alawi M, Santer R, Petrovski S, Kuismin O, Korpi-Heikkilä S, Pietilainen O, Aarno P, Kurki MI, Hoischen A, Need AC, Goldstein DB, Kortüm F.

Am J Hum Genet. 2016 Oct 6;99(4):991-999. doi: 10.1016/j.ajhg.2016.08.017.

PMID:
27693232
4.

Animal-based studies will be essential for precision medicine.

Lloyd KC, Robinson PN, MacRae CA.

Sci Transl Med. 2016 Aug 17;8(352):352ed12. doi: 10.1126/scitranslmed.aaf5474. No abstract available.

PMID:
27535618
5.

The Future of Cardiovascular Education and Training.

Brown DW, MacRae CA, Gardner TJ.

Circulation. 2016 Jun 21;133(25):2734-42. doi: 10.1161/CIRCULATIONAHA.116.023554. No abstract available.

PMID:
27324367
6.

The Future of Genetics and Genomics: Closing the Phenotype Gap in Precision Medicine.

MacRae CA, Vasan RS.

Circulation. 2016 Jun 21;133(25):2634-9. doi: 10.1161/CIRCULATIONAHA.116.022547. No abstract available.

PMID:
27324359
7.

The Future of Cardiovascular Therapeutics.

MacRae CA, Roden DM, Loscalzo J.

Circulation. 2016 Jun 21;133(25):2610-7. doi: 10.1161/CIRCULATIONAHA.116.023555. No abstract available.

PMID:
27324356
8.

The Future of Cardiovascular Biomedicine.

MacRae CA, Loscalzo J.

Circulation. 2016 Jun 21;133(25):2601-2. doi: 10.1161/CIRCULATIONAHA.115.020553. No abstract available.

PMID:
27324354
9.

Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy.

Chelko SP, Asimaki A, Andersen P, Bedja D, Amat-Alarcon N, DeMazumder D, Jasti R, MacRae CA, Leber R, Kleber AG, Saffitz JE, Judge DP.

JCI Insight. 2016 Apr 21;1(5). pii: e85923.

10.

Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators.

Musso G, Mosimann C, Panáková D, Burger A, Zhou Y, Zon LI, MacRae CA.

Genom Data. 2015 Sep 16;6:199-201. doi: 10.1016/j.gdata.2015.09.015.

11.

Comprehensive red blood cell and platelet antigen prediction from whole genome sequencing: proof of principle.

Lane WJ, Westhoff CM, Uy JM, Aguad M, Smeland-Wagman R, Kaufman RM, Rehm HL, Green RC, Silberstein LE; MedSeq Project..

Transfusion. 2016 Mar;56(3):743-54. doi: 10.1111/trf.13416.

12.

In vitro and in vivo reprogramming for the conduction system.

MacRae CA.

Trends Cardiovasc Med. 2016 Jan;26(1):21-2. doi: 10.1016/j.tcm.2015.08.005. No abstract available.

PMID:
26632016
13.

Glucocorticoids enhance muscle endurance and ameliorate Duchenne muscular dystrophy through a defined metabolic program.

Morrison-Nozik A, Anand P, Zhu H, Duan Q, Sabeh M, Prosdocimo DA, Lemieux ME, Nordsborg N, Russell AP, MacRae CA, Gerber AN, Jain MK, Haldar SM.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):E6780-9. doi: 10.1073/pnas.1512968112.

14.

Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015.

Antman EM, Benjamin EJ, Harrington RA, Houser SR, Peterson ED, Bauman MA, Brown N, Bufalino V, Califf RM, Creager MA, Daugherty A, Demets DL, Dennis BP, Ebadollahi S, Jessup M, Lauer MS, Lo B, MacRae CA, McConnell MV, McCray AT, Mello MM, Mueller E, Newburger JW, Okun S, Packer M, Philippakis A, Ping P, Prasoon P, Roger VL, Singer S, Temple R, Turner MB, Vigilante K, Warner J, Wayte P; American Heart Association Data Sharing Summit Attendees..

J Am Heart Assoc. 2015 Nov 5;4(11). pii: e002810. doi: 10.1161/JAHA.115.002810.

15.

The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3.

Cullere X, Plovie E, Bennett PM, MacRae CA, Mayadas TN.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14284-9. doi: 10.1073/pnas.1510495112.

16.

Effect Size Does Matter: The Long Road to Mechanistic Insight From Genome-Wide Association.

MacRae CA, Pollak MR.

Circulation. 2015 Nov 24;132(21):1943-5. doi: 10.1161/CIRCULATIONAHA.115.019306. No abstract available.

17.

Zebrafish as tools for drug discovery.

MacRae CA, Peterson RT.

Nat Rev Drug Discov. 2015 Oct;14(10):721-31. doi: 10.1038/nrd4627. Review.

PMID:
26361349
18.

Chamber identity programs drive early functional partitioning of the heart.

Mosimann C, Panáková D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon LI.

Nat Commun. 2015 Aug 26;6:8146. doi: 10.1038/ncomms9146.

19.

A Critical Need for Clinical Context in the Genomic Era.

MacRae CA.

Circulation. 2015 Sep 15;132(11):992-3. doi: 10.1161/CIRCULATIONAHA.115.018371. No abstract available.

20.

Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration.

Mahmoud AI, O'Meara CC, Gemberling M, Zhao L, Bryant DM, Zheng R, Gannon JB, Cai L, Choi WY, Egnaczyk GF, Burns CE, Burns CG, MacRae CA, Poss KD, Lee RT.

Dev Cell. 2015 Aug 24;34(4):387-99. doi: 10.1016/j.devcel.2015.06.017.

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