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Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.

Natoni A, Farrell ML, Harris S, Falank C, Kirkham-McCarthy L, Macauley MS, Reagan MR, O' Dwyer M.

Haematologica. 2019 May 17. pii: haematol.2018.212266. doi: 10.3324/haematol.2018.212266. [Epub ahead of print]


Exploiting CD22 To Selectively Tolerize Autoantibody Producing B-Cells in Rheumatoid Arthritis.

Bednar KJ, Nycholat CM, Rao TS, Paulson JC, Fung-Leung WP, Macauley MS.

ACS Chem Biol. 2019 Apr 19;14(4):644-654. doi: 10.1021/acschembio.8b01018. Epub 2019 Mar 20.


CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen.

Duan S, Koziol-White CJ, Jester WF Jr, Nycholat CM, Macauley MS, Panettieri RA Jr, Paulson JC.

J Clin Invest. 2019 Mar 1;129(3):1387-1401. doi: 10.1172/JCI125456. Epub 2019 Feb 18.


Antigenic Liposomes for Generation of Disease-specific Antibodies.

Bednar KJ, Hardy L, Smeekens J, Raghuwanshi D, Duan S, Kulis MD, Macauley MS.

J Vis Exp. 2018 Oct 25;(140). doi: 10.3791/58285.


Hypersialylation in Cancer: Modulation of Inflammation and Therapeutic Opportunities.

Rodrigues E, Macauley MS.

Cancers (Basel). 2018 Jun 18;10(6). pii: E207. doi: 10.3390/cancers10060207. Review.


Cell-based glycan arrays for probing glycan-glycan binding protein interactions.

Briard JG, Jiang H, Moremen KW, Macauley MS, Wu P.

Nat Commun. 2018 Feb 28;9(1):880. doi: 10.1038/s41467-018-03245-5.


Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β.

Han KH, Arlian BM, Macauley MS, Paulson JC, Lerner RA.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E372-E381. doi: 10.1073/pnas.1719259115. Epub 2018 Jan 2.


Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens.

Spiller F, Nycholat CM, Kikuchi C, Paulson JC, Macauley MS.

J Immunol. 2018 Feb 1;200(3):949-956. doi: 10.4049/jimmunol.1701257. Epub 2017 Dec 29.


Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model.

Bednar KJ, Shanina E, Ballet R, Connors EP, Duan S, Juan J, Arlian BM, Kulis MD, Butcher EC, Fung-Leung WP, Rao TS, Paulson JC, Macauley MS.

J Immunol. 2017 Nov 1;199(9):3116-3128. doi: 10.4049/jimmunol.1700898. Epub 2017 Sep 29.


Tools for Studying Glycans: Recent Advances in Chemoenzymatic Glycan Labeling.

Lopez Aguilar A, Briard JG, Yang L, Ovryn B, Macauley MS, Wu P.

ACS Chem Biol. 2017 Mar 17;12(3):611-621. doi: 10.1021/acschembio.6b01089. Epub 2017 Feb 13. Review.


Encapsulating an Immunosuppressant Enhances Tolerance Induction by Siglec-Engaging Tolerogenic Liposomes.

Pang L, Macauley MS, Arlian BM, Nycholat CM, Paulson JC.

Chembiochem. 2017 Jul 4;18(13):1226-1233. doi: 10.1002/cbic.201600702. Epub 2017 Apr 4.


Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay.

Murinello S, Moreno SK, Macauley MS, Sakimoto S, Westenskow PD, Friedlander M.

J Vis Exp. 2016 Oct 18;(116). doi: 10.3791/54677.


Reproducing SIVΔnef vaccine correlates of protection: trimeric gp41 antibody concentrated at mucosal front lines.

Voss JE, Macauley MS, Rogers KA, Villinger F, Duan L, Shang L, Fink EA, Andrabi R, Colantonio AD, Robinson JE, Johnson RP, Burton DR, Haase AT.

AIDS. 2016 Oct 23;30(16):2427-2438.


Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2.

Orgel KA, Duan S, Wright BL, Maleki SJ, Wolf JC, Vickery BP, Burks AW, Paulson JC, Kulis MD, Macauley MS.

J Allergy Clin Immunol. 2017 Jan;139(1):366-369.e2. doi: 10.1016/j.jaci.2016.06.053. Epub 2016 Aug 20. No abstract available.


Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.

McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M, Menis S, Cottrell CA, Torres JL, Hsueh J, Schief WR, Wilson IA, Ward AB, Sanders RW, Burton DR.

Cell Rep. 2016 Aug 30;16(9):2327-38. doi: 10.1016/j.celrep.2016.07.074. Epub 2016 Aug 18.


Siglec-F is a novel intestinal M cell marker.

Gicheva N, Macauley MS, Arlian BM, Paulson JC, Kawasaki N.

Biochem Biophys Res Commun. 2016 Oct 7;479(1):1-4. doi: 10.1016/j.bbrc.2016.08.055. Epub 2016 Aug 11.


Targeting Selectins and Their Ligands in Cancer.

Natoni A, Macauley MS, O'Dwyer ME.

Front Oncol. 2016 Apr 18;6:93. doi: 10.3389/fonc.2016.00093. eCollection 2016. Review.


Transfection of microRNA Mimics Should Be Used with Caution.

Jin HY, Gonzalez-Martin A, Miletic AV, Lai M, Knight S, Sabouri-Ghomi M, Head SR, Macauley MS, Rickert RC, Xiao C.

Front Genet. 2015 Dec 2;6:340. doi: 10.3389/fgene.2015.00340. eCollection 2015.


Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.

Macauley MS, Kawasaki N, Peng W, Wang SH, He Y, Arlian BM, McBride R, Kannagi R, Khoo KH, Paulson JC.

J Biol Chem. 2015 Dec 11;290(50):30066-77. doi: 10.1074/jbc.M115.691337. Epub 2015 Oct 27.


Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.

Angata T, Nycholat CM, Macauley MS.

Trends Pharmacol Sci. 2015 Oct;36(10):645-660. doi: 10.1016/ Review.

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