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Items: 1 to 20 of 95

1.

Publisher Correction: c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells.

Gabryšová L, Alvarez-Martinez M, Luisier R, Cox LS, Sodenkamp J, Hosking C, Pérez-Mazliah D, Whicher C, Kannan Y, Potempa K, Wu X, Bhaw L, Wende H, Sieweke MH, Elgar G, Wilson M, Briscoe J, Metzis V, Langhorne J, Luscombe NM, O'Garra A.

Nat Immunol. 2019 Feb 8. doi: 10.1038/s41590-019-0331-3. [Epub ahead of print]

PMID:
30733606
2.

Target-Specific Precision of CRISPR-Mediated Genome Editing.

Chakrabarti AM, Henser-Brownhill T, Monserrat J, Poetsch AR, Luscombe NM, Scaffidi P.

Mol Cell. 2018 Dec 10. pii: S1097-2765(18)31001-3. doi: 10.1016/j.molcel.2018.11.031. [Epub ahead of print]

3.

Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis.

Poetsch AR, Boulton SJ, Luscombe NM.

Genome Biol. 2018 Dec 7;19(1):215. doi: 10.1186/s13059-018-1582-2.

4.

Nervous System Regionalization Entails Axial Allocation before Neural Differentiation.

Metzis V, Steinhauser S, Pakanavicius E, Gouti M, Stamataki D, Ivanovitch K, Watson T, Rayon T, Mousavy Gharavy SN, Lovell-Badge R, Luscombe NM, Briscoe J.

Cell. 2018 Nov 1;175(4):1105-1118.e17. doi: 10.1016/j.cell.2018.09.040. Epub 2018 Oct 18.

5.

Somatic TP53 Mutations Are Detectable in Circulating Tumor DNA from Children with Anaplastic Wilms Tumors.

Treger TD, Chagtai T, Butcher R, Cresswell GD, Al-Saadi R, Brok J, Williams RD, Roberts C, Luscombe NM, Pritchard Jones K, Mifsud W.

Transl Oncol. 2018 Dec;11(6):1301-1306. doi: 10.1016/j.tranon.2018.08.006. Epub 2018 Aug 29.

6.

Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease.

Steele AJ, Denaxas SC, Shah AD, Hemingway H, Luscombe NM.

PLoS One. 2018 Aug 31;13(8):e0202344. doi: 10.1371/journal.pone.0202344. eCollection 2018.

7.

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing.

Attig J, Agostini F, Gooding C, Chakrabarti AM, Singh A, Haberman N, Zagalak JA, Emmett W, Smith CWJ, Luscombe NM, Ule J.

Cell. 2018 Aug 23;174(5):1067-1081.e17. doi: 10.1016/j.cell.2018.07.001. Epub 2018 Aug 2.

8.

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.

Luisier R, Tyzack GE, Hall CE, Mitchell JS, Devine H, Taha DM, Malik B, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R.

Nat Commun. 2018 May 22;9(1):2010. doi: 10.1038/s41467-018-04373-8.

9.

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells.

Gabryšová L, Alvarez-Martinez M, Luisier R, Cox LS, Sodenkamp J, Hosking C, Pérez-Mazliah D, Whicher C, Kannan Y, Potempa K, Wu X, Bhaw L, Wende H, Sieweke MH, Elgar G, Wilson M, Briscoe J, Metzis V, Langhorne J, Luscombe NM, O'Garra A.

Nat Immunol. 2018 May;19(5):497-507. doi: 10.1038/s41590-018-0083-5. Epub 2018 Apr 16. Erratum in: Nat Immunol. 2019 Feb 8;:.

10.

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Horswell S, Chambers T, O'Brien T, Lopez JI, Watkins TBK, Nicol D, Stares M, Challacombe B, Hazell S, Chandra A, Mitchell TJ, Au L, Eichler-Jonsson C, Jabbar F, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Stewart A, Xing W, Smith JC, Escudero M, Huffman A, Matthews N, Elgar G, Phillimore B, Costa M, Begum S, Ward S, Salm M, Boeing S, Fisher R, Spain L, Navas C, Grönroos E, Hobor S, Sharma S, Aurangzeb I, Lall S, Polson A, Varia M, Horsfield C, Fotiadis N, Pickering L, Schwarz RF, Silva B, Herrero J, Luscombe NM, Jamal-Hanjani M, Rosenthal R, Birkbak NJ, Wilson GA, Pipek O, Ribli D, Krzystanek M, Csabai I, Szallasi Z, Gore M, McGranahan N, Van Loo P, Campbell P, Larkin J, Swanton C; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):595-610.e11. doi: 10.1016/j.cell.2018.03.043. Epub 2018 Apr 12.

11.

Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome.

Li C, Lenhard B, Luscombe NM.

Genome Res. 2018 May;28(5):676-688. doi: 10.1101/gr.231449.117. Epub 2018 Apr 4.

12.

Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells.

Ghahramani A, Donati G, Luscombe NM, Watt FM.

Genome Biol. 2018 Jan 15;19(1):3. doi: 10.1186/s13059-017-1384-y.

13.

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.

Hall CE, Yao Z, Choi M, Tyzack GE, Serio A, Luisier R, Harley J, Preza E, Arber C, Crisp SJ, Watson PMD, Kullmann DM, Abramov AY, Wray S, Burley R, Loh SHY, Martins LM, Stevens MM, Luscombe NM, Sibley CR, Lakatos A, Ule J, Gandhi S, Patani R.

Cell Rep. 2017 May 30;19(9):1739-1749. doi: 10.1016/j.celrep.2017.05.024.

14.

GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data.

Mifsud B, Martincorena I, Darbo E, Sugar R, Schoenfelder S, Fraser P, Luscombe NM.

PLoS One. 2017 Apr 5;12(4):e0174744. doi: 10.1371/journal.pone.0174744. eCollection 2017. Erratum in: PLoS One. 2017 May 3;12 (5):e0177280.

15.

Using hiCLIP to identify RNA duplexes that interact with a specific RNA-binding protein.

Sugimoto Y, Chakrabarti AM, Luscombe NM, Ule J.

Nat Protoc. 2017 Mar;12(3):611-637. doi: 10.1038/nprot.2016.188. Epub 2017 Feb 23.

PMID:
28230851
16.

Backmasking in the yeast genome: encoding overlapping information for protein-coding and RNA degradation.

Cakiroglu SA, Zaugg JB, Luscombe NM.

Nucleic Acids Res. 2016 Sep 30;44(17):8065-72. doi: 10.1093/nar/gkw683. Epub 2016 Aug 4.

17.

Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications.

Cresswell GD, Apps JR, Chagtai T, Mifsud B, Bentley CC, Maschietto M, Popov SD, Weeks ME, Olsen ØE, Sebire NJ, Pritchard-Jones K, Luscombe NM, Williams RD, Mifsud W.

EBioMedicine. 2016 Jul;9:120-129. doi: 10.1016/j.ebiom.2016.05.029. Epub 2016 May 27.

18.

Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.

Chlamydas S, Holz H, Samata M, Chelmicki T, Georgiev P, Pelechano V, Dündar F, Dasmeh P, Mittler G, Cadete FT, Ramírez F, Conrad T, Wei W, Raja S, Manke T, Luscombe NM, Steinmetz LM, Akhtar A.

Nat Struct Mol Biol. 2016 Jun;23(6):580-9. doi: 10.1038/nsmb.3233. Epub 2016 May 16.

PMID:
27183194
19.

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation.

Blake SM, Stricker SH, Halavach H, Poetsch AR, Cresswell G, Kelly G, Kanu N, Marino S, Luscombe NM, Pollard SM, Behrens A.

Elife. 2016 Mar 17;5. pii: e08711. doi: 10.7554/eLife.08711.

20.

Intergenic Alu exonisation facilitates the evolution of tissue-specific transcript ends.

Tajnik M, Vigilante A, Braun S, Hänel H, Luscombe NM, Ule J, Zarnack K, König J.

Nucleic Acids Res. 2015 Dec 2;43(21):10492-505. doi: 10.1093/nar/gkv956. Epub 2015 Sep 22.

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