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Items: 16


The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection.

Uppuluri P, Lin L, Alqarihi A, Luo G, Youssef EG, Alkhazraji S, Yount NY, Ibrahim BA, Bolaris MA, Edwards JE Jr, Swidergall M, Filler SG, Yeaman MR, Ibrahim AS.

PLoS Pathog. 2018 May 10;14(5):e1007056. doi: 10.1371/journal.ppat.1007056. eCollection 2018 May.


Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Gebremariam T, Alkhazraji S, Lin L, Wiederhold NP, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00390-17. doi: 10.1128/AAC.00390-17. Print 2017 Sep.


Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients.

Reardon MJ, Van Mieghem NM, Popma JJ, Kleiman NS, S√łndergaard L, Mumtaz M, Adams DH, Deeb GM, Maini B, Gada H, Chetcuti S, Gleason T, Heiser J, Lange R, Merhi W, Oh JK, Olsen PS, Piazza N, Williams M, Windecker S, Yakubov SJ, Grube E, Makkar R, Lee JS, Conte J, Vang E, Nguyen H, Chang Y, Mugglin AS, Serruys PW, Kappetein AP; SURTAVI Investigators.

N Engl J Med. 2017 Apr 6;376(14):1321-1331. doi: 10.1056/NEJMoa1700456. Epub 2017 Mar 17.


Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis.

Gebremariam T, Lin L, Liu M, Kontoyiannis DP, French S, Edwards JE Jr, Filler SG, Ibrahim AS.

J Clin Invest. 2016 Jun 1;126(6):2280-94. doi: 10.1172/JCI82744. Epub 2016 May 9.


Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine.

Liu M, Lin L, Gebremariam T, Luo G, Skory CD, French SW, Chou TF, Edwards JE Jr, Ibrahim AS.

PLoS Pathog. 2015 May 14;11(5):e1004842. doi: 10.1371/journal.ppat.1004842. eCollection 2015 May.


Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection.

Luo G, Lin L, Ibrahim AS, Baquir B, Pantapalangkoor P, Bonomo RA, Doi Y, Adams MD, Russo TA, Spellberg B.

PLoS One. 2012;7(1):e29446. doi: 10.1371/journal.pone.0029446. Epub 2012 Jan 10.


Luminescent-activated transfected killer cells to monitor leukocyte trafficking during systemic bacterial and fungal infection.

Lin L, Ibrahim AS, Baquir B, Palosaari A, Spellberg B.

J Infect Dis. 2012 Jan 15;205(2):337-47. doi: 10.1093/infdis/jir725. Epub 2011 Nov 28.


The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis.

Ibrahim AS, Gebremariam T, Lin L, Luo G, Husseiny MI, Skory CD, Fu Y, French SW, Edwards JE Jr, Spellberg B.

Mol Microbiol. 2010 Aug;77(3):587-604. doi: 10.1111/j.1365-2958.2010.07234.x. Epub 2010 Jun 1.


Safety and efficacy of activated transfected killer cells for neutropenic fungal infections.

Lin L, Ibrahim AS, Baquir B, Fu Y, Applebaum D, Schwartz J, Wang A, Avanesian V, Spellberg B.

J Infect Dis. 2010 Jun 1;201(11):1708-17. doi: 10.1086/652496.


Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice.

Lin L, Ibrahim AS, Xu X, Farber JM, Avanesian V, Baquir B, Fu Y, French SW, Edwards JE Jr, Spellberg B.

PLoS Pathog. 2009 Dec;5(12):e1000703. doi: 10.1371/journal.ppat.1000703. Epub 2009 Dec 24.


Immunological reactivity of blood from healthy humans to the rAls3p-N vaccine protein.

Baquir B, Lin L, Ibrahim AS, Fu Y, Avanesian V, Tu A, Edwards J Jr, Spellberg B.

J Infect Dis. 2010 Feb 1;201(3):473-7. doi: 10.1086/649901.


Immunological surrogate marker of rAls3p-N vaccine-induced protection against Staphylococcus aureus.

Lin L, Ibrahim AS, Baquir B, Avanesian V, Fu Y, Spellberg B.

FEMS Immunol Med Microbiol. 2009 Apr;55(3):293-5. doi: 10.1111/j.1574-695X.2008.00531.x. Epub 2009 Jan 13. No abstract available.


The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus.

Spellberg B, Ibrahim AS, Yeaman MR, Lin L, Fu Y, Avanesian V, Bayer AS, Filler SG, Lipke P, Otoo H, Edwards JE Jr.

Infect Immun. 2008 Oct;76(10):4574-80. doi: 10.1128/IAI.00700-08. Epub 2008 Jul 21.


Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity.

Spellberg B, Ibrahim AS, Lin L, Avanesian V, Fu Y, Lipke P, Otoo H, Ho T, Edwards JE Jr.

J Infect Dis. 2008 Apr 1;197(7):967-71. doi: 10.1086/529204.


Considerable differences in vaccine immunogenicities and efficacies related to the diluent used for aluminum hydroxide adjuvant.

Lin L, Ibrahim AS, Avanesian V, Edwards JE Jr, Fu Y, Baquir B, Taub R, Spellberg B.

Clin Vaccine Immunol. 2008 Mar;15(3):582-4. doi: 10.1128/CVI.00427-07. Epub 2008 Jan 9.


The iron chelator deferasirox protects mice from mucormycosis through iron starvation.

Ibrahim AS, Gebermariam T, Fu Y, Lin L, Husseiny MI, French SW, Schwartz J, Skory CD, Edwards JE Jr, Spellberg BJ.

J Clin Invest. 2007 Sep;117(9):2649-57.

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