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Items: 1 to 20 of 206

1.

Anticancer effect of Limonin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice and the inhibition of A549 cell proliferation through apoptotic pathway.

Gong C, Qi L, Huo Y, Zhang S, Ning X, Bai L, Wang Z.

J Biochem Mol Toxicol. 2019 Dec;33(12):e22374. doi: 10.1002/jbt.22374. Epub 2019 Nov 8.

PMID:
31702096
2.

Nanodelivery and anticancer effect of a limonoid, nimbolide, in breast and pancreatic cancer cells.

Patra A, Satpathy S, Hussain MD.

Int J Nanomedicine. 2019 Oct 7;14:8095-8104. doi: 10.2147/IJN.S208540. eCollection 2019.

3.

Secophragmalin-Type Limonoids from Trichilia connaroides: Isolation, Semisynthesis, and Their Cytotoxic Activities.

Solipeta DR, Bandi S, Vemulapalli SPB, Pallavi PMC, Vemireddy S, Balasubramania S, Mahabalarao SKH, Katragadda SB.

J Nat Prod. 2019 Oct 25;82(10):2731-2743. doi: 10.1021/acs.jnatprod.9b00346. Epub 2019 Oct 7.

PMID:
31589431
4.

Disruption of Epigenetic Silencing in Human Colon Cancer Cells Lines Utilizing a Novel Supercritical CO2 Extract of Neem Leaf (Azadirachta indica).

Qiu Z, Andrijauskaite K, Morris J, Wargovich MJ.

Anticancer Res. 2019 Oct;39(10):5473-5481. doi: 10.21873/anticanres.13740.

PMID:
31570441
5.

Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.

Gao L, Sang JZ, Cao H.

Biomed Pharmacother. 2019 Oct;118:109366. doi: 10.1016/j.biopha.2019.109366. Epub 2019 Aug 23.

6.

Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity.

Wang N, Fan Y, Yuan CM, Song J, Yao Y, Liu W, Gajendran B, Zacksenhaus E, Li Y, Liu J, Hao XJ, Ben-David Y.

BMC Cancer. 2019 Aug 2;19(1):764. doi: 10.1186/s12885-019-5914-8.

7.

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.

Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK.

Nat Chem Biol. 2019 Jul;15(7):747-755. doi: 10.1038/s41589-019-0304-8. Epub 2019 Jun 17.

8.

Limonin provokes hepatocellular carcinoma cells with stemness entry into cycle via activating PI3K/Akt signaling.

Tang Z, Tang Y, Li L, Liu T, Yang J.

Biomed Pharmacother. 2019 Sep;117:109051. doi: 10.1016/j.biopha.2019.109051. Epub 2019 Jun 6.

9.

Limonin attenuates the stemness of breast cancer cells via suppressing MIR216A methylation.

Su Z, Wang C, Chang D, Zhu X, Sai C, Pei J.

Biomed Pharmacother. 2019 Apr;112:108699. doi: 10.1016/j.biopha.2019.108699. Epub 2019 Feb 27.

10.

[Chemical constituents from root barks of Dictamnus dasycarpus and their cytotoxic activities].

Guo XX, Zhao LN, Wang J, Liu S, Bi QR, Wang Z, Tan NH.

Zhongguo Zhong Yao Za Zhi. 2018 Dec;43(24):4869-4877. doi: 10.19540/j.cnki.cjcmm.20180926.002. Chinese.

PMID:
30717533
11.

Cytotoxic limonoids from the bark of Walsura cochinchinensis.

Trinh BTD, Nguyen HD, Nguyen HT, Pham PD, Ngo NTN, Nguyen LT, Nguyen LTT, Bui DN, Dang SV, Nguyen LD.

Fitoterapia. 2019 Mar;133:75-79. doi: 10.1016/j.fitote.2018.11.008. Epub 2018 Dec 19.

PMID:
30576797
12.

Synthesis of the seco-Limonoid BCD Ring System Identifies a Hsp90 Chaperon Machinery (p23) Inhibitor.

Pinkerton DM, Chow S, Eisa NH, Kainth K, Vanden Berg TJ, Burns JM, Guddat LW, Savage GP, Chadli A, Williams CM.

Chemistry. 2019 Jan 28;25(6):1451-1455. doi: 10.1002/chem.201805420. Epub 2018 Dec 20.

PMID:
30570197
13.

Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation.

Mahmoud N, Saeed MEM, Sugimoto Y, Klauck SM, Greten HJ, Efferth T.

Oncotarget. 2018 Nov 6;9(87):35762-35779. doi: 10.18632/oncotarget.26299. eCollection 2018 Nov 6.

14.

Citrus peels prevent cancer.

Nair S A, Sr RK, Nair AS, Baby S.

Phytomedicine. 2018 Nov 15;50:231-237. doi: 10.1016/j.phymed.2017.08.011. Epub 2017 Aug 17.

PMID:
30466983
15.

Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer.

Sophia J, Kowshik J, Dwivedi A, Bhutia SK, Manavathi B, Mishra R, Nagini S.

Cell Death Dis. 2018 Oct 23;9(11):1087. doi: 10.1038/s41419-018-1126-4.

16.

Limonoids from seeds of Azadirachta indica A. Juss. and their cytotoxic activity.

Chen J, Fan X, Zhu J, Song L, Li Z, Lin F, Yu R, Xu H, Zi J.

Acta Pharm Sin B. 2018 Jul;8(4):639-644. doi: 10.1016/j.apsb.2017.12.009. Epub 2018 Feb 1.

17.

Gedunin, A Neem Limonoid in Combination with Epalrestat Inhibits Cancer Hallmarks by Attenuating Aldose Reductase-Driven Oncogenic Signaling in SCC131 Oral Cancer Cells.

Tanagala KKK, Baba AB, Kowshik J, Reddy GB, Nagini S.

Anticancer Agents Med Chem. 2018;18(14):2042-2052. doi: 10.2174/1871520618666180731093433.

PMID:
30062975
18.

Nimbolide induced apoptosis by activating ERK-mediated inhibition of c-IAP1 expression in human hepatocellular carcinoma cells.

Hsueh KC, Lin CL, Tung JN, Yang SF, Hsieh YH.

Environ Toxicol. 2018 Sep;33(9):913-922. doi: 10.1002/tox.22576. Epub 2018 Jul 2.

PMID:
29962003
19.

Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer.

Pooladanda V, Bandi S, Mondi SR, Gottumukkala KM, Godugu C.

Toxicol In Vitro. 2018 Sep;51:114-128. doi: 10.1016/j.tiv.2018.05.010. Epub 2018 May 17.

PMID:
29778718
20.

A supercritical CO2 extract of neem leaf (A. indica) and its bioactive liminoid, nimbolide, suppresses colon cancer in preclinical models by modulating pro-inflammatory pathways.

Patel MJ, Tripathy S, Mukhopadhyay KD, Wangjam T, Cabang AB, Morris J, Wargovich MJ.

Mol Carcinog. 2018 Sep;57(9):1156-1165. doi: 10.1002/mc.22832. Epub 2018 May 8.

PMID:
29697164

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