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Items: 4

1.

Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.

Qin L, Tian Y, Yu Z, Shi D, Wang J, Zhang C, Peng R, Chen X, Liu C, Chen Y, Huang W, Deng W.

Oncotarget. 2016 Jan 12;7(2):1395-407. doi: 10.18632/oncotarget.6366.

2.

Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.

Kim JS, Eom JI, Cheong JW, Choi AJ, Lee JK, Yang WI, Min YH.

Clin Cancer Res. 2007 Feb 1;13(3):1019-28.

3.

The role of PKC and PDK1 in monocyte lineage specification by Ras.

Pearn L, Fisher J, Burnett AK, Darley RL.

Blood. 2007 May 15;109(10):4461-9. Epub 2007 Jan 25.

4.

Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.

Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N Jr, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M.

Cancer Res. 2006 Apr 1;66(7):3737-46.

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