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Multiomics analyses of two Leonurus species illuminate leonurine biosynthesis and its evolution.
Li P, Yan MX, Liu P, Yang DJ, He ZK, Gao Y, Jiang Y, Kong Y, Zhong X, Wu S, Yang J, Wang HX, Huang YB, Wang L, Chen XY, Hu YH, Zhao Q, Xu P. Li P, et al. Mol Plant. 2024 Jan 1;17(1):158-177. doi: 10.1016/j.molp.2023.11.003. Epub 2023 Nov 10. Mol Plant. 2024. PMID: 37950440
Here, we present the chromosome-level genome sequence assemblies of Leonurus japonicus, known for its high leonurine production, and Leonurus sibiricus, characterized by very limited leonurine production. ...Collectively, our comprehensive study illuminates l …
Here, we present the chromosome-level genome sequence assemblies of Leonurus japonicus, known for its high leonurine production, and …
Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts.
Wieczfinska J, Sitarek P, Kowalczyk T, Pawliczak R. Wieczfinska J, et al. Clin Exp Immunol. 2020 Oct;202(1):28-46. doi: 10.1111/cei.13481. Epub 2020 Jul 18. Clin Exp Immunol. 2020. PMID: 32562256 Free PMC article.
The aim of this study was to evaluate the anti-remodeling properties of extracts from transformed and transgenic Leonurus sibiricus roots with transformed L. sibiricus roots extract with transcriptional factor AtPAP1 overexpression (AtPAP1). Two fibroblast ce …
The aim of this study was to evaluate the anti-remodeling properties of extracts from transformed and transgenic Leonurus sibiricu …
Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation.
Kim JH, Kim M, Jung HS, Sohn Y. Kim JH, et al. Int J Mol Med. 2019 Sep;44(3):913-926. doi: 10.3892/ijmm.2019.4269. Epub 2019 Jul 8. Int J Mol Med. 2019. PMID: 31524244 Free PMC article.
Leonurus sibiricus L. (LS) is a medicinal plant used in East Asia, Europe and the USA. ...
Leonurus sibiricus L. (LS) is a medicinal plant used in East Asia, Europe and the USA. ...
Anticancer Activity of Leonurus sibiricus L.: Possible Involvement of Intrinsic Apoptotic Pathway.
Krishnan V, Subramaniam S, Chia-Chuan C, Venkatachalam B, Thomas Cheeran A, Chi-Ying F H. Krishnan V, et al. Nutr Cancer. 2022;74(1):225-236. doi: 10.1080/01635581.2020.1870702. Epub 2021 Jan 12. Nutr Cancer. 2022. PMID: 33432822
The aim of this study was to evaluate the methanolic extract of aerial parts of Leonurus sibiricus L (LS) for its anticancer activity on HCC cell lines. ...
The aim of this study was to evaluate the methanolic extract of aerial parts of Leonurus sibiricus L (LS) for its anticancer a …
Standardization of Leonurus sibiricus L. aerial part and capillary electrophoresis quantitative analysis of its leonurine content.
Suwatronnakorn M, Issaravanich S, Palanuvej C, Ruangrungsi N. Suwatronnakorn M, et al. J Adv Pharm Technol Res. 2021 Jul-Sep;12(3):291-297. doi: 10.4103/japtr.JAPTR_243_21. Epub 2021 Jul 16. J Adv Pharm Technol Res. 2021. PMID: 34345610 Free PMC article.
The quality parameters of Leonurus sibiricus L. aerial part crude drugs were evaluated. Fifteen crude drugs were collected from various locations throughout Thailand. ...CE was beneficial technique for the analysis of leonurine in L. sibiricus aerial parts... …
The quality parameters of Leonurus sibiricus L. aerial part crude drugs were evaluated. Fifteen crude drugs were collected fro …
Identification of Leonurus sibiricus as a Weed Reservoir for Three Pepper-Infecting Viruses.
Kwon SJ, Choi GS, Yoon JY, Seo JK, Choi HS. Kwon SJ, et al. Plant Pathol J. 2016 Feb;32(1):65-9. doi: 10.5423/PPJ.NT.07.2015.0138. Epub 2016 Feb 1. Plant Pathol J. 2016. PMID: 26889117 Free PMC article.
In plant virus ecology, weeds are regarded as wild reservoirs of viruses and as potential sources for insect-mediated transmission of viruses. During field surveys in 2013-2014, three Leonurus sibiricus plants showing virus-like symptoms were collected from pepper f …
In plant virus ecology, weeds are regarded as wild reservoirs of viruses and as potential sources for insect-mediated transmission of viruse …
Labdane and ent-halimane diterpenoids with STAT3-inhibitory activity from Leonurus sibiricus.
Wang C, Tian J, Liu C, He Y, Li J, Zhang Q, Xiao T, Xie C, Yang C. Wang C, et al. Phytochemistry. 2023 Oct;214:113802. doi: 10.1016/j.phytochem.2023.113802. Epub 2023 Jul 26. Phytochemistry. 2023. PMID: 37506992
Nine undescribed labdane diterpenoids (1-9) and one undescribed ent-halimane diterpenoid (10) were isolated from the aerial parts of Leonurus sibiricus, together with four known analogues (11-14) during our searching for naturally occurring antitumor agents. ...
Nine undescribed labdane diterpenoids (1-9) and one undescribed ent-halimane diterpenoid (10) were isolated from the aerial parts of Leon …
Comparative transcriptome analysis of sesquiterpene biosynthesis and functional characterization of sesquiterpene synthases in Leonurus sibiricus L.
Yan X, Li W, Liang D, Zhao G, Caiyin Q, Qiao J. Yan X, et al. Planta. 2021 Feb 18;253(3):71. doi: 10.1007/s00425-021-03586-4. Planta. 2021. PMID: 33604817
Two sesquiterpene synthases were identified through comparative transcriptome analysis of Leonurus sibiricus. LsSqTPS2 could produce high titer of delta-cadinene in vivo which suggests the terpene specificity of L. sibiricus. Leonurus sibiricus …
Two sesquiterpene synthases were identified through comparative transcriptome analysis of Leonurus sibiricus. LsSqTPS2 could p …
Labdane diterpenoids from Leonurus sibiricus.
Wu H, Fronczek FR, Ferreira D, Burandt CL Jr, Zjawiony JK. Wu H, et al. J Nat Prod. 2011 Apr 25;74(4):831-6. doi: 10.1021/np100956k. Epub 2011 Mar 4. J Nat Prod. 2011. PMID: 21375312 Free PMC article.
Six new labdane diterpenoids, preleosibirone A (1), 13-epi-preleosibirone A (2), isopreleosibirone A (3), leosibirone A (4), leosibirone B (5), and 15-epi-leosibirone B (6), were isolated from the leaves of Leonurus sibiricus. The absolute configurations of 1, 2, 5, …
Six new labdane diterpenoids, preleosibirone A (1), 13-epi-preleosibirone A (2), isopreleosibirone A (3), leosibirone A (4), leosibirone B ( …
Quantitation of phenylpropanoids and iridoids in insulin-sensitising extracts of Leonurus sibiricus L. (Lamiaceae).
Pitschmann A, Zehl M, Heiss E, Purevsuren S, Urban E, Dirsch VM, Glasl S. Pitschmann A, et al. Phytochem Anal. 2016 Jan-Feb;27(1):23-31. doi: 10.1002/pca.2583. Epub 2015 Sep 2. Phytochem Anal. 2016. PMID: 26333151
OBJECTIVES: To provide a validated quantitation method for the quality control of Leonurus sibiricus and to prove in vitro insulin-sensitisation, thereby supporting the traditional use of Leonurus sibiricus. METHODOLOGY: Pulverised Leonurus s …
OBJECTIVES: To provide a validated quantitation method for the quality control of Leonurus sibiricus and to prove in vitro ins …
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