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Items: 1 to 20 of 119

1.

Kras and Lkb1 mutations synergistically induce intraductal papillary mucinous neoplasm derived from pancreatic duct cells.

Collet L, Ghurburrun E, Meyers N, Assi M, Pirlot B, Leclercq IA, Couvelard A, Komuta M, Cros J, Demetter P, Lemaigre FP, Borbath I, Jacquemin P.

Gut. 2019 Jun 1. pii: gutjnl-2018-318059. doi: 10.1136/gutjnl-2018-318059. [Epub ahead of print]

PMID:
31154393
2.

Mechanical stimuli control liver homeostasis.

Lemaigre FP.

J Hepatol. 2019 Apr 26. pii: S0168-8278(19)30229-6. doi: 10.1016/j.jhep.2019.04.002. [Epub ahead of print] No abstract available.

PMID:
31036351
3.

Comparison of the Opn-CreER and Ck19-CreER Drivers in Bile Ducts of Normal and Injured Mouse Livers.

Lesaffer B, Verboven E, Van Huffel L, Moya IM, van Grunsven LA, Leclercq IA, Lemaigre FP, Halder G.

Cells. 2019 Apr 25;8(4). pii: E380. doi: 10.3390/cells8040380.

4.

Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma.

Gérard C, Di-Luoffo M, Gonay L, Caruso S, Couchy G, Loriot A, Castven D, Tao J, Konobrocka K, Cordi S, Monga SP, Hanert E, Marquardt JU, Zucman-Rossi J, Lemaigre FP.

J Hepatol. 2019 Apr 4. pii: S0168-8278(19)30195-3. doi: 10.1016/j.jhep.2019.03.024. [Epub ahead of print]

PMID:
30953666
5.

Liver and Pancreas: Do Similar Embryonic Development and Tissue Organization Lead to Similar Mechanisms of Tumorigenesis?

Ghurburrun E, Borbath I, Lemaigre FP, Jacquemin P.

Gene Expr. 2018 Aug 22;18(3):149-155. doi: 10.3727/105221618X15216414278706. Epub 2018 Mar 26. Review.

6.

Development of the liver: Insights into organ and tissue morphogenesis.

Ober EA, Lemaigre FP.

J Hepatol. 2018 May;68(5):1049-1062. doi: 10.1016/j.jhep.2018.01.005. Epub 2018 Jan 13. Review.

PMID:
29339113
7.

MicroRNA-337-3p controls hepatobiliary gene expression and transcriptional dynamics during hepatic cell differentiation.

Demarez C, Gérard C, Cordi S, Poncy A, Achouri Y, Dauguet N, Rosa DA, Gunning PT, Manfroid I, Lemaigre FP.

Hepatology. 2018 Jan;67(1):313-327. doi: 10.1002/hep.29475. Epub 2017 Nov 16.

PMID:
28833283
8.

Chronic pancreatitis and lipomatosis are associated with defective function of ciliary genes in pancreatic ductal cells.

Augereau C, Collet L, Vargiu P, Guerra C, Ortega S, Lemaigre FP, Jacquemin P.

Hum Mol Genet. 2016 Nov 15;25(22):5017-5026. doi: 10.1093/hmg/ddw332.

PMID:
28159992
9.

Vps33b is crucial for structural and functional hepatocyte polarity.

Hanley J, Dhar DK, Mazzacuva F, Fiadeiro R, Burden JJ, Lyne AM, Smith H, Straatman-Iwanowska A, Banushi B, Virasami A, Mills K, Lemaigre FP, Knisely AS, Howe S, Sebire N, Waddington SN, Paulusma CC, Clayton P, Gissen P.

J Hepatol. 2017 May;66(5):1001-1011. doi: 10.1016/j.jhep.2017.01.001. Epub 2017 Jan 9.

10.

Gene regulatory networks in differentiation and direct reprogramming of hepatic cells.

Gérard C, Tys J, Lemaigre FP.

Semin Cell Dev Biol. 2017 Jun;66:43-50. doi: 10.1016/j.semcdb.2016.12.003. Epub 2016 Dec 12. Review.

PMID:
27979774
11.

Expression of Molecular Differentiation Markers Does Not Correlate with Histological Differentiation Grade in Intrahepatic Cholangiocarcinoma.

Demarez C, Hubert C, Sempoux C, Lemaigre FP.

PLoS One. 2016 Jun 9;11(6):e0157140. doi: 10.1371/journal.pone.0157140. eCollection 2016.

12.

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsée J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE.

Development. 2016 Jun 1;143(11):1958-70. doi: 10.1242/dev.134171. Epub 2016 Apr 11.

13.

Extraction of high-quality RNA from pancreatic tissues for gene expression studies.

Augereau C, Lemaigre FP, Jacquemin P.

Anal Biochem. 2016 May 1;500:60-2. doi: 10.1016/j.ab.2016.02.008. Epub 2016 Feb 17.

PMID:
26896683
14.

Role of β-catenin in development of bile ducts.

Cordi S, Godard C, Saandi T, Jacquemin P, Monga SP, Colnot S, Lemaigre FP.

Differentiation. 2016 Jan-Mar;91(1-3):42-9. doi: 10.1016/j.diff.2016.02.001. Epub 2016 Feb 5.

15.

LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.

Just PA, Poncy A, Charawi S, Dahmani R, Traore M, Dumontet T, Drouet V, Dumont F, Gilgenkrantz H, Colnot S, Terris B, Coulouarn C, Lemaigre F, Perret C.

PLoS One. 2015 Dec 21;10(12):e0145400. doi: 10.1371/journal.pone.0145400. eCollection 2015.

16.

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.

Mu X, Español-Suñer R, Mederacke I, Affò S, Manco R, Sempoux C, Lemaigre FP, Adili A, Yuan D, Weber A, Unger K, Heikenwälder M, Leclercq IA, Schwabe RF.

J Clin Invest. 2015 Oct 1;125(10):3891-903. doi: 10.1172/JCI77995. Epub 2015 Sep 8.

17.

Proliferation-Independent Initiation of Biliary Cysts in Polycystic Liver Diseases.

Beaudry JB, Cordi S, Demarez C, Lepreux S, Pierreux CE, Lemaigre FP.

PLoS One. 2015 Jun 30;10(6):e0132295. doi: 10.1371/journal.pone.0132295. eCollection 2015.

18.

Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.

Poncy A, Antoniou A, Cordi S, Pierreux CE, Jacquemin P, Lemaigre FP.

Dev Biol. 2015 Aug 15;404(2):136-48. doi: 10.1016/j.ydbio.2015.05.012. Epub 2015 May 29.

19.

Determining the fate of hepatic cells by lineage tracing: facts and pitfalls.

Lemaigre FP.

Hepatology. 2015 Jun;61(6):2100-3. doi: 10.1002/hep.27659. Epub 2015 Apr 15. Review.

PMID:
25503476
20.

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH.

Dev Biol. 2014 Dec 15;396(2):201-13. doi: 10.1016/j.ydbio.2014.10.002. Epub 2014 Oct 18.

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