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Items: 1 to 20 of 116

1.

Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology.

Buckner MM, Blair JM, La Ragione RM, Newcombe J, Dwyer DJ, Ivens A, Piddock LJ.

MBio. 2016 Nov 22;7(6). pii: e01916-16. doi: 10.1128/mBio.01916-16.

2.

Assess drug-resistance phenotypes, not just genotypes.

Piddock LJ.

Nat Microbiol. 2016 Jul 26;1(8):16120. doi: 10.1038/nmicrobiol.2016.120. No abstract available.

PMID:
27573119
3.

How to Measure Export via Bacterial Multidrug Resistance Efflux Pumps.

Blair JM, Piddock LJ.

MBio. 2016 Jul 5;7(4). pii: e00840-16. doi: 10.1128/mBio.00840-16.

4.

Erratum for Richmond et al., The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner.

Richmond GE, Evans LP, Anderson MJ, Wand ME, Bonney LC, Ivens A, Chua KL, Webber MA, Sutton JM, Peterson ML, Piddock LJ.

MBio. 2016 Jun 21;7(3). pii: e00852-16. doi: 10.1128/mBio.00852-16. No abstract available.

5.

Ask the experts: how to curb antibiotic resistance and plug the antibiotics gap?

Piddock L, Garneau-Tsodikova S, Garner C.

Future Med Chem. 2016 Jun;8(10):1027-32. doi: 10.4155/fmc-2014-0032. No abstract available.

6.

Reflecting on the final report of the O'Neill Review on Antimicrobial Resistance.

Piddock LJ.

Lancet Infect Dis. 2016 Jul;16(7):767-8. doi: 10.1016/S1473-3099(16)30127-X. No abstract available.

PMID:
27208976
7.

The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner.

Richmond GE, Evans LP, Anderson MJ, Wand ME, Bonney LC, Ivens A, Chua KL, Webber MA, Sutton JM, Peterson ML, Piddock LJ.

MBio. 2016 Apr 19;7(2):e00430-16. doi: 10.1128/mBio.00430-16. Erratum in: MBio. 2016;7(3). pii: e00852-16. doi: 10.1128/mBio.00852-16.

8.

Ciprofloxacin and ceftriaxone alter cytokine responses, but not Toll-like receptors, to Salmonella infection in vitro.

Anuforom O, Wallace GR, Buckner MM, Piddock LJ.

J Antimicrob Chemother. 2016 Jul;71(7):1826-33. doi: 10.1093/jac/dkw092.

PMID:
27076102
9.

Inactivation or inhibition of AcrAB-TolC increases resistance of carbapenemase-producing Enterobacteriaceae to carbapenems.

Saw HT, Webber MA, Mushtaq S, Woodford N, Piddock LJ.

J Antimicrob Chemother. 2016 Jun;71(6):1510-9. doi: 10.1093/jac/dkw028.

PMID:
26945714
10.

Understanding the mechanisms and drivers of antimicrobial resistance.

Holmes AH, Moore LS, Sundsfjord A, Steinbakk M, Regmi S, Karkey A, Guerin PJ, Piddock LJ.

Lancet. 2016 Jan 9;387(10014):176-87. doi: 10.1016/S0140-6736(15)00473-0. Review.

PMID:
26603922
11.

Nonmedical Uses of Antibiotics: Time to Restrict Their Use?

Meek RW, Vyas H, Piddock LJ.

PLoS Biol. 2015 Oct 7;13(10):e1002266. doi: 10.1371/journal.pbio.1002266.

12.

Teixobactin, the first of a new class of antibiotics discovered by iChip technology?

Piddock LJ.

J Antimicrob Chemother. 2015 Oct;70(10):2679-80. doi: 10.1093/jac/dkv175. Review.

PMID:
26089440
13.

Laura Piddock: Fights antibiotic resistance.

Piddock L.

BMJ. 2015 May 14;350:h2471. doi: 10.1136/bmj.h2471. No abstract available.

PMID:
25976523
14.

Parallel evolutionary pathways to antibiotic resistance selected by biocide exposure.

Webber MA, Whitehead RN, Mount M, Loman NJ, Pallen MJ, Piddock LJ.

J Antimicrob Chemother. 2015 Aug;70(8):2241-8. doi: 10.1093/jac/dkv109.

15.

A novel gene amplification causes upregulation of the PatAB ABC transporter and fluoroquinolone resistance in Streptococcus pneumoniae.

Baylay AJ, Ivens A, Piddock LJ.

Antimicrob Agents Chemother. 2015;59(6):3098-108. doi: 10.1128/AAC.04858-14.

16.

AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.

Blair JM, Bavro VN, Ricci V, Modi N, Cacciotto P, KleinekathÓ§fer U, Ruggerone P, Vargiu AV, Baylay AJ, Smith HE, Brandon Y, Galloway D, Piddock LJ.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3511-6. doi: 10.1073/pnas.1419939112.

17.

Antibiotic research and development: business as usual?

Harbarth S, Theuretzbacher U, Hackett J; DRIVE-AB consortium..

J Antimicrob Chemother. 2015;70(6):1604-7. doi: 10.1093/jac/dkv020.

PMID:
25673635
18.

Molecular mechanisms of antibiotic resistance.

Blair JM, Webber MA, Baylay AJ, Ogbolu DO, Piddock LJ.

Nat Rev Microbiol. 2015 Jan;13(1):42-51. doi: 10.1038/nrmicro3380. Review.

PMID:
25435309
20.

Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance.

Blair JM, Richmond GE, Piddock LJ.

Future Microbiol. 2014;9(10):1165-77. doi: 10.2217/fmb.14.66. Review.

PMID:
25405886
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