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Items: 1 to 20 of 35

1.

β-Lapachone Regulates Obesity through Modulating Thermogenesis in Brown Adipose Tissue and Adipocytes: Role of AMPK Signaling Pathway.

Kwak HJ, Jeong MY, Um JY, Park J.

Am J Chin Med. 2019 May 16:1-20. doi: 10.1142/S0192415X19500423. [Epub ahead of print]

PMID:
31094212
2.

Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson's Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways.

Park JS, Leem YH, Park JE, Kim DY, Kim HS.

Biomol Ther (Seoul). 2019 Mar 1;27(2):178-184. doi: 10.4062/biomolther.2018.234.

3.

Amelioration of Huntington's disease phenotypes by Beta-Lapachone is associated with increases in Sirt1 expression, CREB phosphorylation and PGC-1α deacetylation.

Lee M, Ban JJ, Chung JY, Im W, Kim M.

PLoS One. 2018 May 9;13(5):e0195968. doi: 10.1371/journal.pone.0195968. eCollection 2018.

4.

Development and Validation of an Analytical Method Readily Applicable for Quality Control of Tabebuia impetiginosa (Taheebo) Ethanolic Extract.

Jin Y, Jeong KM, Lee J, Zhao J, Choi SY, Baek KS.

J AOAC Int. 2018 May 1;101(3):695-700. doi: 10.5740/jaoacint.17-0228. Epub 2017 Sep 19.

PMID:
28927490
5.

β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway.

Kee JY, Han YH, Kim DS, Mun JG, Park SH, So HS, Park SJ, Park R, Um JY, Hong SH.

PLoS One. 2017 May 8;12(5):e0176937. doi: 10.1371/journal.pone.0176937. eCollection 2017.

6.

β-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells.

Kee JY, Han YH, Park J, Kim DS, Mun JG, Ahn KS, Kim HJ, Um JY, Hong SH.

Integr Cancer Ther. 2017 Dec;16(4):585-596. doi: 10.1177/1534735416681638. Epub 2016 Dec 5.

7.

Oral Lapacho-Based Medication: An Easy, Safe, and Feasible Support to Prevent and/or Reduce Oral Mucositis During Radiotherapy for Head and Neck Cancer.

Giacomelli I, Scartoni D, Fiammetta M, Baki M, Zei G, Muntoni C, Cappelli S, Greto D, Scoccianti S, Livi L.

Nutr Cancer. 2015;67(8):1247-53. doi: 10.1080/01635581.2015.1082114. Epub 2015 Oct 9.

PMID:
26451712
8.

Biofertilization with Azospirillum brasilense improves in vitro culture of Handroanthus ochraceus, a forestry, ornamental and medicinal plant.

Llorente BE, Alasia MA, Larraburu EE.

N Biotechnol. 2016 Jan 25;33(1):32-40. doi: 10.1016/j.nbt.2015.07.006. Epub 2015 Aug 5.

PMID:
26255131
9.

β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia.

Lee EJ, Ko HM, Jeong YH, Park EM, Kim HS.

J Neuroinflammation. 2015 Jul 16;12:133. doi: 10.1186/s12974-015-0355-z.

10.

Downregulation of Sp1 is involved in β-lapachone-induced cell cycle arrest and apoptosis in oral squamous cell carcinoma.

Jeon YJ, Bang W, Shin JC, Park SM, Cho JJ, Choi YH, Seo KS, Choi NJ, Shim JH, Chae JI.

Int J Oncol. 2015;46(6):2606-12. doi: 10.3892/ijo.2015.2972. Epub 2015 Apr 20.

PMID:
25891355
11.

Melanogenesis inhibition of β-lapachone, a natural product from Tabebuia avellanedae, with effective in vivo lightening potency.

Kim JH, Lee SM, Myung CH, Lee KR, Hyun SM, Lee JE, Park YS, Jeon SR, Park JI, Chang SE, Hwang JS.

Arch Dermatol Res. 2015 Apr;307(3):229-38. doi: 10.1007/s00403-015-1543-5. Epub 2015 Feb 8.

PMID:
25663088
12.

Mechanistic studies of cancer cell mitochondria- and NQO1-mediated redox activation of beta-lapachone, a potentially novel anticancer agent.

Li JZ, Ke Y, Misra HP, Trush MA, Li YR, Zhu H, Jia Z.

Toxicol Appl Pharmacol. 2014 Dec 15;281(3):285-93. doi: 10.1016/j.taap.2014.10.012. Epub 2014 Oct 29.

PMID:
25448047
13.

Synthesis and structure-activity relationships of lapacho analogues. 2. Modification of the basic naphtho[2,3-b]furan-4,9-dione, redox activation, and suppression of human keratinocyte hyperproliferation by 8-hydroxynaphtho[2,3-b]thiophene-4,9-diones.

Bannwitz S, Krane D, Vortherms S, Kalin T, Lindenschmidt C, Zahedi Golpayegani N, Tentrop J, Prinz H, Müller K.

J Med Chem. 2014 Jul 24;57(14):6226-39. doi: 10.1021/jm500754d. Epub 2014 Jul 7.

PMID:
24964246
14.

Comparative metabolism study of β-lapachone in mouse, rat, dog, monkey, and human liver microsomes using liquid chromatography-tandem mass spectrometry.

Lee S, Kim IS, Kwak TH, Yoo HH.

J Pharm Biomed Anal. 2013 Sep;83:286-92. doi: 10.1016/j.jpba.2013.05.028. Epub 2013 May 28.

PMID:
23777616
15.

Synergistic enhancement of antitumor effect of β-Lapachone by photodynamic induction of quinone oxidoreductase (NQO1).

Lamberti MJ, Vittar NB, da Silva Fde C, Ferreira VF, Rivarola VA.

Phytomedicine. 2013 Aug 15;20(11):1007-12. doi: 10.1016/j.phymed.2013.04.018. Epub 2013 Jun 7.

PMID:
23746950
16.

Synthesis and anti-inflammatory evaluations of β-lapachone derivatives.

Tseng CH, Cheng CM, Tzeng CC, Peng SI, Yang CL, Chen YL.

Bioorg Med Chem. 2013 Jan 15;21(2):523-31. doi: 10.1016/j.bmc.2012.10.047. Epub 2012 Nov 24.

PMID:
23232148
17.

β-Lapachone ameliorization of experimental autoimmune encephalomyelitis.

Xu J, Wagoner G, Douglas JC, Drew PD.

J Neuroimmunol. 2013 Jan 15;254(1-2):46-54. doi: 10.1016/j.jneuroim.2012.09.004. Epub 2012 Sep 23.

19.

Lapacho tea (Tabebuia impetiginosa) extract inhibits pancreatic lipase and delays postprandial triglyceride increase in rats.

Kiage-Mokua BN, Roos N, Schrezenmeir J.

Phytother Res. 2012 Dec;26(12):1878-83. doi: 10.1002/ptr.4659. Epub 2012 Mar 17.

PMID:
22431070
20.

Lapachol as an epithelial tumor inhibitor agent in Drosophila melanogaster heterozygote for tumor suppressor gene wts.

Costa WF, Oliveira AB, Nepomuceno JC.

Genet Mol Res. 2011 Dec 22;10(4):3236-45. doi: 10.4238/2011.December.22.1.

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