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Items: 1 to 20 of 154

1.

Transcriptional regulation of Translocator protein (18 kDa) (TSPO) in microglia requires Pu.1, Ap1 and Sp factors.

Rashid K, Geissl L, Wolf A, Karlstetter M, Langmann T.

Biochim Biophys Acta Gene Regul Mech. 2018 Dec;1861(12):1119-1133. doi: 10.1016/j.bbagrm.2018.10.018. Epub 2018 Nov 6.

PMID:
30412797
2.

Testing for Known Retinal Degeneration Mutants in Mouse Strains.

Rashid K, Dannhausen K, Langmann T.

Methods Mol Biol. 2019;1834:45-58. doi: 10.1007/978-1-4939-8669-9_3.

PMID:
30324435
3.

Correction: Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations.

Van Schil K, Naessens S, Van de Sompele S, Carron M, Aslanidis A, Van Cauwenbergh C, Mayer AK, Van Heetvelde M, Bauwens M, Verdin H, Coppieters F, Greenberg ME, Yang MG, Karlstetter M, Langmann T, De Preter K, Kohl S, Cherry TJ, Leroy BP; CNV Study Group, De Baere E.

Genet Med. 2018 Oct 8. doi: 10.1038/s41436-018-0305-0. [Epub ahead of print]

PMID:
30297699
4.

Modulation of three key innate immune pathways for the most common retinal degenerative diseases.

Akhtar-Schäfer I, Wang L, Krohne TU, Xu H, Langmann T.

EMBO Mol Med. 2018 Oct;10(10). pii: e8259. doi: 10.15252/emmm.201708259. Review.

5.

Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration.

Di Pierdomenico J, Scholz R, Valiente-Soriano FJ, Sánchez-Migallón MC, Vidal-Sanz M, Langmann T, Agudo-Barriuso M, García-Ayuso D, Villegas-Pérez MP.

Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4392-4403. doi: 10.1167/iovs.18-24621.

PMID:
30193320
6.

The Phenotype of Monocytes in Anterior Uveitis Depends on the HLA-B27 Status.

Kasper M, Walscheid K, Laffer B, Bauer D, Busch M, Wildschütz L, Wang B, Loser K, Vogl T, Grajewski RS, Langmann T, Heiligenhaus A.

Front Immunol. 2018 Jul 30;9:1773. doi: 10.3389/fimmu.2018.01773. eCollection 2018.

7.

Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage.

Dannhausen K, Möhle C, Langmann T.

Dis Model Mech. 2018 Sep 5;11(9). pii: dmm033597. doi: 10.1242/dmm.033597.

8.

Microglia Activation and Immunomodulatory Therapies for Retinal Degenerations.

Rashid K, Wolf A, Langmann T.

Front Cell Neurosci. 2018 Jun 21;12:176. doi: 10.3389/fncel.2018.00176. eCollection 2018. Review.

9.

Resveratrol induces dynamic changes to the microglia transcriptome, inhibiting inflammatory pathways and protecting against microglia-mediated photoreceptor apoptosis.

Wiedemann J, Rashid K, Langmann T.

Biochem Biophys Res Commun. 2018 Jun 18;501(1):239-245. doi: 10.1016/j.bbrc.2018.04.223. Epub 2018 May 4.

PMID:
29723528
10.

Further Characterization of the Predominant Inner Retinal Degeneration of Aging Cln3 Δex7/8 Knock-In Mice.

Volz C, Mirza M, Langmann T, Jägle H.

Adv Exp Med Biol. 2018;1074:403-411. doi: 10.1007/978-3-319-75402-4_50.

PMID:
29721970
11.

Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina.

Beck SC, Karlstetter M, Garcia Garrido M, Feng Y, Dannhausen K, Mühlfriedel R, Sothilingam V, Seebauer B, Berger W, Hammes HP, Seeliger MW, Langmann T.

Sci Rep. 2018 Apr 13;8(1):5970. doi: 10.1038/s41598-018-24476-y.

12.

Microglia Analysis in Retinal Degeneration Mouse Models.

Dannhausen K, Rashid K, Langmann T.

Methods Mol Biol. 2018;1753:159-166. doi: 10.1007/978-1-4939-7720-8_10.

PMID:
29564787
13.

Blockade of microglial adenosine A2A receptor impacts inflammatory mechanisms, reduces ARPE-19 cell dysfunction and prevents photoreceptor loss in vitro.

Madeira MH, Rashid K, Ambrósio AF, Santiago AR, Langmann T.

Sci Rep. 2018 Feb 2;8(1):2272. doi: 10.1038/s41598-018-20733-2.

14.

Crocin, a plant-derived carotenoid, modulates microglial reactivity.

Yorgun MA, Rashid K, Aslanidis A, Bresgen C, Dannhausen K, Langmann T.

Biochem Biophys Rep. 2017 Oct 2;12:245-250. doi: 10.1016/j.bbrep.2017.09.007. eCollection 2017 Dec.

15.

Regulated efflux of photoreceptor outer segment-derived cholesterol by human RPE cells.

Storti F, Raphael G, Griesser V, Klee K, Drawnel F, Willburger C, Scholz R, Langmann T, von Eckardstein A, Fingerle J, Grimm C, Maugeais C.

Exp Eye Res. 2017 Dec;165:65-77. doi: 10.1016/j.exer.2017.09.008. Epub 2017 Sep 21.

PMID:
28943268
16.

Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations.

Van Schil K, Naessens S, Van de Sompele S, Carron M, Aslanidis A, Van Cauwenbergh C, Kathrin Mayer A, Van Heetvelde M, Bauwens M, Verdin H, Coppieters F, Greenberg ME, Yang MG, Karlstetter M, Langmann T, De Preter K, Kohl S, Cherry TJ, Leroy BP; CNV Study Group, De Baere E.

Genet Med. 2018 Feb;20(2):202-213. doi: 10.1038/gim.2017.97. Epub 2017 Jul 27. Erratum in: Genet Med. 2018 Oct 8;:.

17.

[New Therapeutic Approaches in Inflammatory Diseases of the Eye - Targeting Lymphangiogenesis and Cellular Immunity: Research Unit FOR 2240 Presents Itself].

Cursiefen C, Bock F, Clahsen T, Regenfuss B, Reis A, Steven P, Heindl LM, Bosch JJ, Hos D, Eming S, Grajewski R, Heiligenhaus A, Fauser S, Austin J, Langmann T.

Klin Monbl Augenheilkd. 2017 May;234(5):679-685. doi: 10.1055/s-0043-108247. Epub 2017 May 15. Review. German.

PMID:
28505676
18.

Comprehensive analysis of mouse retinal mononuclear phagocytes.

Lückoff A, Scholz R, Sennlaub F, Xu H, Langmann T.

Nat Protoc. 2017 Jun;12(6):1136-1150. doi: 10.1038/nprot.2017.032. Epub 2017 May 4.

PMID:
28471458
19.

[Polysialic Acid for Immunomodulation in an Animal Model for Wet Age-Related Macular Degeneration (AMD)].

Langmann T, Fauser S.

Klin Monbl Augenheilkd. 2017 May;234(5):657-661. doi: 10.1055/s-0043-105138. Epub 2017 Apr 5. German.

PMID:
28380648
20.

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

Grassmann F, Kiel C, Zimmermann ME, Gorski M, Grassmann V, Stark K; International AMD Genomics Consortium (IAMDGC), Heid IM, Weber BH.

Genome Med. 2017 Mar 27;9(1):29. doi: 10.1186/s13073-017-0418-0.

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