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Items: 1 to 20 of 64

1.

EFFECTS OF INHALED FLUTICASONE PROPIONATE ON EXTRINSIC TONGUE MUSCLES IN RATS.

Setzke C, Broytman O, Russell JA, Morel N, Sonsalla M, Lamming DW, Connor NP, Teodorescu M.

J Appl Physiol (1985). 2020 Jan 16. doi: 10.1152/japplphysiol.00359.2019. [Epub ahead of print]

PMID:
31944881
2.

A toolbox for the longitudinal assessment of healthspan in aging mice.

Bellantuono I, de Cabo R, Ehninger D, Di Germanio C, Lawrie A, Miller J, Mitchell SJ, Navas-Enamorado I, Potter PK, Tchkonia T, Trejo JL, Lamming DW.

Nat Protoc. 2020 Jan 8. doi: 10.1038/s41596-019-0256-1. [Epub ahead of print]

PMID:
31915391
3.

Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension.

Yu D, Tomasiewicz JL, Yang SE, Miller BR, Wakai MH, Sherman DS, Cummings NE, Baar EL, Brinkman JA, Syed FA, Lamming DW.

Cell Rep. 2019 Oct 1;29(1):236-248.e3. doi: 10.1016/j.celrep.2019.08.084.

4.

Corrigendum to: Next Generation Strategies for Geroprotection via mTORC1 Inhibition.

Dumas SN, Lamming DW.

J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):73. doi: 10.1093/gerona/glz199. No abstract available.

5.

TORwards a Victory Over Aging.

Lamming DW, Salmon AB.

J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):1-3. doi: 10.1093/gerona/glz212. No abstract available.

PMID:
31544928
6.

Hypothalamic mTORC2 is essential for metabolic health and longevity.

Chellappa K, Brinkman JA, Mukherjee S, Morrison M, Alotaibi MI, Carbajal KA, Alhadeff AL, Perron IJ, Yao R, Purdy CS, DeFelice DM, Wakai MH, Tomasiewicz J, Lin A, Meyer E, Peng Y, Arriola Apelo SI, Puglielli L, Betley JN, Paschos GK, Baur JA, Lamming DW.

Aging Cell. 2019 Oct;18(5):e13014. doi: 10.1111/acel.13014. Epub 2019 Aug 1.

7.

A novel rapamycin analog is highly selective for mTORC1 in vivo.

Schreiber KH, Arriola Apelo SI, Yu D, Brinkman JA, Velarde MC, Syed FA, Liao CY, Baar EL, Carbajal KA, Sherman DS, Ortiz D, Brunauer R, Yang SE, Tzannis ST, Kennedy BK, Lamming DW.

Nat Commun. 2019 Jul 19;10(1):3194. doi: 10.1038/s41467-019-11174-0.

8.

Next Generation Strategies for Geroprotection via mTORC1 Inhibition.

Dumas SN, Lamming DW.

J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):14-23. doi: 10.1093/gerona/glz056. Erratum in: J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):73.

PMID:
30794726
9.

The Metabolic Response to a Low Amino Acid Diet is Independent of Diet-Induced Shifts in the Composition of the Gut Microbiome.

Pak HH, Cummings NE, Green CL, Brinkman JA, Yu D, Tomasiewicz JL, Yang SE, Boyle C, Konon EN, Ong IM, Lamming DW.

Sci Rep. 2019 Jan 11;9(1):67. doi: 10.1038/s41598-018-37177-3.

10.

Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice.

De Leon ER, Brinkman JA, Fenske RJ, Gregg T, Schmidt BA, Sherman DS, Cummings NE, Peter DC, Kimple ME, Lamming DW, Merrins MJ.

Sci Rep. 2018 Dec 13;8(1):17814. doi: 10.1038/s41598-018-36289-0.

11.

Aging and drug discovery.

Bakula D, Aliper AM, Mamoshina P, Petr MA, Teklu A, Baur JA, Campisi J, Ewald CY, Georgievskaya A, Gladyshev VN, Kovalchuk O, Lamming DW, Luijsterburg MS, Martín-Montalvo A, Maudsley S, Mkrtchyan GV, Moskalev A, Olshansky SJ, Ozerov IV, Pickett A, Ristow M, Zhavoronkov A, Scheibye-Knudsen M.

Aging (Albany NY). 2018 Nov 13;10(11):3079-3088. doi: 10.18632/aging.101646.

12.

Lysosome: The metabolic signaling hub.

Lamming DW, Bar-Peled L.

Traffic. 2019 Jan;20(1):27-38. doi: 10.1111/tra.12617. Epub 2018 Nov 14. Review.

13.

Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype.

Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L.

Aging Cell. 2018 Oct;17(5):e12820. doi: 10.1111/acel.12820. Epub 2018 Jul 27.

14.

Regulation of metabolic health by essential dietary amino acids.

Green CL, Lamming DW.

Mech Ageing Dev. 2019 Jan;177:186-200. doi: 10.1016/j.mad.2018.07.004. Epub 2018 Jul 22. Review.

15.

Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.

Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH.

Nature. 2018 Aug;560(7717):E26. doi: 10.1038/s41586-018-0187-y.

PMID:
29849139
16.

Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms.

Yu D, Yang SE, Miller BR, Wisinski JA, Sherman DS, Brinkman JA, Tomasiewicz JL, Cummings NE, Kimple ME, Cryns VL, Lamming DW.

FASEB J. 2018 Jun;32(6):3471-3482. doi: 10.1096/fj.201701211R. Epub 2018 Jan 30.

17.

Short-term consumption of a plant protein diet does not improve glucose homeostasis of young C57BL/6J mice.

Lamming DW, Baar EL, Arriola Apelo SI, Tosti V, Fontana L.

Nutr Healthy Aging. 2017 Dec 7;4(3):239-245. doi: 10.3233/NHA-170025.

18.

Restoration of metabolic health by decreased consumption of branched-chain amino acids.

Cummings NE, Williams EM, Kasza I, Konon EN, Schaid MD, Schmidt BA, Poudel C, Sherman DS, Yu D, Arriola Apelo SI, Cottrell SE, Geiger G, Barnes ME, Wisinski JA, Fenske RJ, Matkowskyj KA, Kimple ME, Alexander CM, Merrins MJ, Lamming DW.

J Physiol. 2018 Feb 15;596(4):623-645. doi: 10.1113/JP275075. Epub 2017 Dec 27.

19.

SYK kinase mediates brown fat differentiation and activation.

Knoll M, Winther S, Natarajan A, Yang H, Jiang M, Thiru P, Shahsafaei A, Chavarria TE, Lamming DW, Sun L, Hansen JB, Lodish HF.

Nat Commun. 2017 Dec 13;8(1):2115. doi: 10.1038/s41467-017-02162-3.

20.

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

Moretti J, Roy S, Bozec D, Martinez J, Chapman JR, Ueberheide B, Lamming DW, Chen ZJ, Horng T, Yeretssian G, Green DR, Blander JM.

Cell. 2017 Nov 2;171(4):809-823.e13. doi: 10.1016/j.cell.2017.09.034. Epub 2017 Oct 19.

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