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Items: 1 to 20 of 57

1.

Identification of suitable controls for miRNA quantification in T-cells and whole blood cells in sepsis.

Hirschberger S, Hübner M, Strauß G, Effinger D, Bauer M, Weis S, Giamarellos-Bourboulis EJ, Kreth S.

Sci Rep. 2019 Oct 31;9(1):15735. doi: 10.1038/s41598-019-51782-w.

2.

Myeloid-Derived Suppressor Cells Mediate Immunosuppression After Cardiopulmonary Bypass.

Hübner M, Tomasi R, Effinger D, Wu T, Klein G, Bender M, Kilger E, Juchem G, Schwedhelm E, Kreth S.

Crit Care Med. 2019 Aug;47(8):e700-e709. doi: 10.1097/CCM.0000000000003820.

PMID:
31149961
3.

Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.

Heun Y, Pircher J, Czermak T, Bluem P, Hupel G, Bohmer M, Kraemer BF, Pogoda K, Pfeifer A, Woernle M, Ribeiro A, Hübner M, Kreth S, Claus RA, Weis S, Ungelenk L, Krötz F, Pohl U, Mannell H.

EBioMedicine. 2019 Apr;42:120-132. doi: 10.1016/j.ebiom.2019.03.034. Epub 2019 Mar 21.

4.

Intronic miR-744 Inhibits Glioblastoma Migration by Functionally Antagonizing Its Host Gene MAP2K4.

Hübner M, Hinske CL, Effinger D, Wu T, Thon N, Kreth FW, Kreth S.

Cancers (Basel). 2018 Oct 25;10(11). pii: E400. doi: 10.3390/cancers10110400.

5.

MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis.

Möhnle P, Hirschberger S, Hinske LC, Briegel J, Hübner M, Weis S, Dimopoulos G, Bauer M, Giamarellos-Bourboulis EJ, Kreth S.

Mol Med. 2018 Oct 17;24(1):54. doi: 10.1186/s10020-018-0056-z.

6.

Dynamic 18F-FET PET is a powerful imaging biomarker in gadolinium-negative gliomas.

Kunz M, Albert NL, Unterrainer M, la Fougere C, Egensperger R, Schüller U, Lutz J, Kreth S, Tonn JC, Kreth FW, Thon N.

Neuro Oncol. 2019 Feb 14;21(2):274-284. doi: 10.1093/neuonc/noy098.

PMID:
29893965
7.

MiRNAs: dynamic regulators of immune cell functions in inflammation and cancer.

Hirschberger S, Hinske LC, Kreth S.

Cancer Lett. 2018 Sep 1;431:11-21. doi: 10.1016/j.canlet.2018.05.020. Epub 2018 May 22. Review.

8.

Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury.

Koeppen M, Lee JW, Seo SW, Brodsky KS, Kreth S, Yang IV, Buttrick PM, Eckle T, Eltzschig HK.

Nat Commun. 2018 Feb 26;9(1):816. doi: 10.1038/s41467-018-03105-2.

9.

Identification and Validation of Potential Differential miRNA Regulation via Alternative Polyadenylation.

Hübner M, Galante PAF, Kreth S, Hinske LC.

Methods Mol Biol. 2018;1733:87-92. doi: 10.1007/978-1-4939-7601-0_7.

PMID:
29435925
10.

MiRIAD update: using alternative polyadenylation, protein interaction network analysis and additional species to enhance exploration of the role of intragenic miRNAs and their host genes.

Hinske LC, Dos Santos FRC, Ohara DT, Ohno-Machado L, Kreth S, Galante PAF.

Database (Oxford). 2017 Jan 1;2017. doi: 10.1093/database/bax053.

11.

Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.

Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaah5360. doi: 10.1126/scitranslmed.aah5360.

12.

MicroRNAs as Clinical Biomarkers and Therapeutic Tools in Perioperative Medicine.

Kreth S, Hübner M, Hinske LC.

Anesth Analg. 2018 Feb;126(2):670-681. doi: 10.1213/ANE.0000000000002444. Review.

PMID:
28922229
13.

Intronic miRNA-641 controls its host Gene's pathway PI3K/AKT and this relationship is dysfunctional in glioblastoma multiforme.

Hinske LC, Heyn J, Hübner M, Rink J, Hirschberger S, Kreth S.

Biochem Biophys Res Commun. 2017 Aug 5;489(4):477-483. doi: 10.1016/j.bbrc.2017.05.175. Epub 2017 May 30.

PMID:
28576488
14.

Soluble intercellular adhesion molecule-1: a potential biomarker for pain intensity in chronic pain patients.

Luchting B, Hinske LC, Rachinger-Adam B, Celi LA, Kreth S, Azad SC.

Biomark Med. 2017 Mar;11(3):265-276. doi: 10.2217/bmm-2016-0246. Epub 2017 Feb 16.

15.

Outcome in unresectable glioblastoma: MGMT promoter methylation makes the difference.

Thon N, Thorsteinsdottir J, Eigenbrod S, Schüller U, Lutz J, Kreth S, Belka C, Tonn JC, Niyazi M, Kreth FW.

J Neurol. 2017 Feb;264(2):350-358. doi: 10.1007/s00415-016-8355-1. Epub 2016 Dec 5.

PMID:
27921166
16.

miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain.

Heyn J, Luchting B, Hinske LC, Hübner M, Azad SC, Kreth S.

J Neuroinflammation. 2016 Sep 20;13(1):248. doi: 10.1186/s12974-016-0712-6.

17.

Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain.

Luchting B, Heyn J, Woehrle T, Rachinger-Adam B, Kreth S, Hinske LC, Azad SC.

J Neuroinflammation. 2016 May 4;13(1):100. doi: 10.1186/s12974-016-0565-z.

18.

Down-regulation of MicroRNA-31 in CD4+ T Cells Contributes to Immunosuppression in Human Sepsis by Promoting TH2 Skewing.

van der Heide V, Möhnle P, Rink J, Briegel J, Kreth S.

Anesthesiology. 2016 Apr;124(4):908-22. doi: 10.1097/ALN.0000000000001031.

PMID:
26978146
19.

Emerging Roles for MicroRNAs in Perioperative Medicine.

Neudecker V, Brodsky KS, Kreth S, Ginde AA, Eltzschig HK.

Anesthesiology. 2016 Feb;124(2):489-506. doi: 10.1097/ALN.0000000000000969. Review.

20.

Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR.

Hinske LC, Galante PA, Limbeck E, Möhnle P, Parmigiani RB, Ohno-Machado L, Camargo AA, Kreth S.

PLoS One. 2015 Mar 23;10(3):e0121507. doi: 10.1371/journal.pone.0121507. eCollection 2015.

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