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Items: 1 to 20 of 110

1.

The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling.

Csukasi F, Duran I, Barad M, Barta T, Gudernova I, Trantirek L, Martin JH, Kuo CY, Woods J, Lee H, Cohn DH, Krejci P, Krakow D.

Sci Transl Med. 2018 Sep 19;10(459). pii: eaat9356. doi: 10.1126/scitranslmed.aat9356.

PMID:
30232230
2.

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.

Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P.

Sci Signal. 2018 Sep 18;11(548). pii: eaap8608. doi: 10.1126/scisignal.aap8608.

PMID:
30228226
3.

Next generation sequencing reveals a novel nonsense mutation in MSX1 gene related to oligodontia.

Bonczek O, Bielik P, Krejčí P, Zeman T, Izakovičová-Hollá L, Šoukalová J, Vaněk J, Gerguri T, Balcar VJ, Šerý O.

PLoS One. 2018 Sep 7;13(9):e0202989. doi: 10.1371/journal.pone.0202989. eCollection 2018.

4.

Colicin FY inhibits pathogenic Yersinia enterocolitica in mice.

Bosák J, Micenková L, Hrala M, Pomorská K, Kunova Bosakova M, Krejci P, Göpfert E, Faldyna M, Šmajs D.

Sci Rep. 2018 Aug 16;8(1):12242. doi: 10.1038/s41598-018-30729-7.

5.

Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cells.

Ghosh S, Scozzaro S, Ramos AR, Delcambre S, Chevalier C, Krejci P, Erneux C.

J Cell Sci. 2018 Aug 16;131(16). pii: jcs216408. doi: 10.1242/jcs.216408.

PMID:
30012834
6.

Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals.

Balek L, Buchtova M, Kunova Bosakova M, Varecha M, Foldynova-Trantirkova S, Gudernova I, Vesela I, Havlik J, Neburkova J, Turner S, Krzyscik MA, Zakrzewska M, Klimaschewski L, Claus P, Trantirek L, Cigler P, Krejci P.

Biomaterials. 2018 Sep;176:106-121. doi: 10.1016/j.biomaterials.2018.05.030. Epub 2018 May 21.

7.

Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies.

Kunova Bosakova M, Varecha M, Hampl M, Duran I, Nita A, Buchtova M, Dosedelova H, Machat R, Xie Y, Ni Z, Martin JH, Chen L, Jansen G, Krakow D, Krejci P.

Hum Mol Genet. 2018 Mar 15;27(6):1093-1105. doi: 10.1093/hmg/ddy031.

PMID:
29360984
8.

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Gudernova I, Balek L, Varecha M, Kucerova JF, Kunova Bosakova M, Fafilek B, Palusova V, Uldrijan S, Trantirek L, Krejci P.

Oncotarget. 2017 Nov 27;8(65):109319-109331. doi: 10.18632/oncotarget.22674. eCollection 2017 Dec 12.

9.

Computer-assisted engineering of hyperstable fibroblast growth factor 2.

Dvorak P, Bednar D, Vanacek P, Balek L, Eiselleova L, Stepankova V, Sebestova E, Kunova Bosakova M, Konecna Z, Mazurenko S, Kunka A, Vanova T, Zoufalova K, Chaloupkova R, Brezovsky J, Krejci P, Prokop Z, Dvorak P, Damborsky J.

Biotechnol Bioeng. 2018 Apr;115(4):850-862. doi: 10.1002/bit.26531. Epub 2018 Jan 24.

PMID:
29278409
10.

Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome.

Balek L, Nemec P, Konik P, Kunova Bosakova M, Varecha M, Gudernova I, Medalova J, Krakow D, Krejci P.

Cell Signal. 2018 Jan;42:144-154. doi: 10.1016/j.cellsig.2017.10.003. Epub 2017 Oct 13.

PMID:
29030113
11.

ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3.

Balek L, Gudernova I, Vesela I, Hampl M, Oralova V, Kunova Bosakova M, Varecha M, Nemec P, Hall T, Abbadessa G, Hatch N, Buchtova M, Krejci P.

Bone. 2017 Dec;105:57-66. doi: 10.1016/j.bone.2017.08.016. Epub 2017 Aug 18.

PMID:
28826843
12.

Tyrosine Kinase Expressed in Hepatocellular Carcinoma, TEC, Controls Pluripotency and Early Cell Fate Decisions of Human Pluripotent Stem Cells via Regulation of Fibroblast Growth Factor-2 Secretion.

Vanova T, Konecna Z, Zbonakova Z, La Venuta G, Zoufalova K, Jelinkova S, Varecha M, Rotrekl V, Krejci P, Nickel W, Dvorak P, Kunova Bosakova M.

Stem Cells. 2017 Sep;35(9):2050-2059. doi: 10.1002/stem.2660. Epub 2017 Jul 6.

13.

Role of Primary Cilia in Odontogenesis.

Hampl M, Cela P, Szabo-Rogers HL, Kunova Bosakova M, Dosedelova H, Krejci P, Buchtova M.

J Dent Res. 2017 Aug;96(9):965-974. doi: 10.1177/0022034517713688. Epub 2017 Jun 12. Review.

14.

Statins do not inhibit the FGFR signaling in chondrocytes.

Fafilek B, Hampl M, Ricankova N, Vesela I, Balek L, Kunova Bosakova M, Gudernova I, Varecha M, Buchtova M, Krejci P.

Osteoarthritis Cartilage. 2017 Sep;25(9):1522-1530. doi: 10.1016/j.joca.2017.05.014. Epub 2017 Jun 3.

15.

A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation.

Bernatik O, Radaszkiewicz T, Behal M, Dave Z, Witte F, Mahl A, Cernohorsky NH, Krejci P, Stricker S, Bryja V.

Front Cell Dev Biol. 2017 May 4;5:47. doi: 10.3389/fcell.2017.00047. eCollection 2017.

16.

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

Gudernova I, Foldynova-Trantirkova S, Ghannamova BE, Fafilek B, Varecha M, Balek L, Hruba E, Jonatova L, Jelinkova I, Kunova Bosakova M, Trantirek L, Mayer J, Krejci P.

Elife. 2017 Feb 15;6. pii: e21536. doi: 10.7554/eLife.21536.

17.

A Chaperone Complex Formed by HSP47, FKBP65, and BiP Modulates Telopeptide Lysyl Hydroxylation of Type I Procollagen.

Duran I, Martin JH, Weis MA, Krejci P, Konik P, Li B, Alanay Y, Lietman C, Lee B, Eyre D, Cohn DH, Krakow D.

J Bone Miner Res. 2017 Jun;32(6):1309-1319. doi: 10.1002/jbmr.3095. Epub 2017 Apr 6.

18.

[Multiple Endocrine Neoplasia I (Wermers Syndrome), Forms of Clinical Manifestation, 5 Case Studies].

Drbalová K, Herdová K, Krejčí P, Nývltová M, Solař S, Vedralová L, Záruba P, Netuka D, Bavor P.

Vnitr Lek. Fall 2016;62(9 Suppl 3):140-149. Czech.

PMID:
27734708
19.

MORN5 Expression during Craniofacial Development and Its Interaction with the BMP and TGFβ Pathways.

Cela P, Hampl M, Fu KK, Kunova Bosakova M, Krejci P, Richman JM, Buchtova M.

Front Physiol. 2016 Aug 31;7:378. doi: 10.3389/fphys.2016.00378. eCollection 2016.

20.

Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport.

Haugsten EM, Sørensen V, Kunova Bosakova M, de Souza GA, Krejci P, Wiedlocha A, Wesche J.

J Proteome Res. 2016 Oct 7;15(10):3841-3855. Epub 2016 Sep 26.

PMID:
27615514

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