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Items: 7

1.

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons.

Koren I, Timms RT, Kula T, Xu Q, Li MZ, Elledge SJ.

Cell. 2018 Jun 14;173(7):1622-1635.e14. doi: 10.1016/j.cell.2018.04.028. Epub 2018 May 17.

PMID:
29779948
2.

A model-driven methodology for exploring complex disease comorbidities applied to autism spectrum disorder and inflammatory bowel disease.

Somekh J, Peleg M, Eran A, Koren I, Feiglin A, Demishtein A, Shiloh R, Heiner M, Kong SW, Elazar Z, Kohane I.

J Biomed Inform. 2016 Oct;63:366-378. doi: 10.1016/j.jbi.2016.08.008. Epub 2016 Aug 10.

3.

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ.

Mol Cell. 2015 Sep 3;59(5):867-81. doi: 10.1016/j.molcel.2015.05.006. Epub 2015 Jun 4.

4.

Cell biology. Promoting tumorigenesis by suppressing autophagy.

Koren I, Kimchi A.

Science. 2012 Nov 16;338(6109):889-90. doi: 10.1126/science.1230577. No abstract available.

PMID:
23161981
5.

Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process.

Koren I, Reem E, Kimchi A.

Autophagy. 2010 Nov;6(8):1179-80. doi: 10.4161/auto.6.8.13338.

6.

DAP1, a novel substrate of mTOR, negatively regulates autophagy.

Koren I, Reem E, Kimchi A.

Curr Biol. 2010 Jun 22;20(12):1093-8. doi: 10.1016/j.cub.2010.04.041. Epub 2010 May 27.

7.

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy.

Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A.

EMBO Rep. 2009 Mar;10(3):285-92. doi: 10.1038/embor.2008.246. Epub 2009 Jan 30.

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