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Items: 1 to 20 of 752

1.

Reply to Brewer: Liver-targeted ALDH2 inhibition may reduce alcohol-seeking behaviors with limited side effects.

Guillot A, Koob GF, Gao B.

Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7573-7574. doi: 10.1073/pnas.2001049117. Epub 2020 Mar 3. No abstract available.

PMID:
32127485
2.

Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice.

Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, Roberts A, Zheng B, Kumar V, Zengler K, Pizzo DP, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob GF, Kisseleva T.

JCI Insight. 2020 Feb 13;5(3). pii: 131277. doi: 10.1172/jci.insight.131277.

3.

An Examination of Child and Adolescent Neurodevelopment Through National Institutes of Health Studies.

Volkow ND, Gordon JA, Koob GF, Birnbaum LS, Clayton JA, Koroshetz WJ, Bianchi DW, Gibbons GH, Riley WT, PĂ©rez-Stable EJ, Croyle RT.

Public Health Rep. 2020 Mar/Apr;135(2):169-172. doi: 10.1177/0033354919900889. Epub 2020 Jan 22. No abstract available.

PMID:
31968205
4.

Opioid use disorder.

Strang J, Volkow ND, Degenhardt L, Hickman M, Johnson K, Koob GF, Marshall BDL, Tyndall M, Walsh SL.

Nat Rev Dis Primers. 2020 Jan 9;6(1):3. doi: 10.1038/s41572-019-0137-5. Review.

PMID:
31919349
5.

Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking.

Guillot A, Ren T, Jourdan T, Pawlosky RJ, Han E, Kim SJ, Zhang L, Koob GF, Gao B.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25974-25981. doi: 10.1073/pnas.1908137116. Epub 2019 Dec 2.

PMID:
31792171
6.

PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease.

Lee JS, Mukhopadhyay P, Matyas C, Trojnar E, Paloczi J, Yang YR, Blank BA, Savage C, Sorokin AV, Mehta NN, Vendruscolo JCM, Koob GF, Vendruscolo LF, Pacher P, Lohoff FW.

Sci Rep. 2019 Nov 20;9(1):17167. doi: 10.1038/s41598-019-53603-6.

7.

A Light in the Darkness: Repetitive Transcranial Magnetic Stimulation (rTMS) to Treat the Hedonic Dysregulation of Addiction.

Pettorruso M, di Giannantonio M, De Risio L, Martinotti G, Koob GF.

J Addict Med. 2019 Nov 12. doi: 10.1097/ADM.0000000000000575. [Epub ahead of print]

PMID:
31725426
8.

Probenecid Reduces Alcohol Drinking in Rodents. Is Pannexin1 a Novel Therapeutic Target for Alcohol Use Disorder?

Tunstall BJ, Lorrai I, McConnell SA, Gazo KL, Zallar LJ, de Guglielmo G, Hoang I, Haass-Koffler CL, Repunte-Canonigo V, Koob GF, Vendruscolo LF, Sanna PP.

Alcohol Alcohol. 2019 Jan 9;54(5):497-502. doi: 10.1093/alcalc/agz054.

9.

Corrigendum: Impulsivity Derived From the Dark Side: Neurocircuits That Contribute to Negative Urgency.

Zorrilla EP, Koob GF.

Front Behav Neurosci. 2019 Aug 27;13:188. doi: 10.3389/fnbeh.2019.00188. eCollection 2019.

10.

Larry Stein: pioneer neuropsychopharmacology researcher, mentor, and friend.

Koob GF.

Neuropsychopharmacology. 2019 Dec;44(13):2294-2295. doi: 10.1038/s41386-019-0509-2. Epub 2019 Sep 9. No abstract available.

PMID:
31501525
11.

Refractory dependence on opioid analgesics.

Ballantyne JC, Sullivan MD, Koob GF.

Pain. 2019 Dec;160(12):2655-2660. doi: 10.1097/j.pain.0000000000001680. No abstract available.

PMID:
31408053
12.

Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement.

Koob GF.

Biol Psychiatry. 2020 Jan 1;87(1):44-53. doi: 10.1016/j.biopsych.2019.05.023. Epub 2019 Jun 12. Review.

PMID:
31400808
13.

Impulsivity Derived From the Dark Side: Neurocircuits That Contribute to Negative Urgency.

Zorrilla EP, Koob GF.

Front Behav Neurosci. 2019 Jun 25;13:136. doi: 10.3389/fnbeh.2019.00136. eCollection 2019. Review. Erratum in: Front Behav Neurosci. 2019 Aug 27;13:188.

14.

Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework.

Koob GF, Colrain IM.

Neuropsychopharmacology. 2020 Jan;45(1):141-165. doi: 10.1038/s41386-019-0446-0. Epub 2019 Jun 24. Review.

PMID:
31234199
15.

Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala.

Tunstall BJ, Kirson D, Zallar LJ, McConnell SA, Vendruscolo JCM, Ho CP, Oleata CS, Khom S, Manning M, Lee MR, Leggio L, Koob GF, Roberto M, Vendruscolo LF.

PLoS Biol. 2019 Apr 16;17(4):e2006421. doi: 10.1371/journal.pbio.2006421. eCollection 2019 Apr.

16.

Periaqueductal Gray Sheds Light on Dark Areas of Psychopathology.

George DT, Ameli R, Koob GF.

Trends Neurosci. 2019 May;42(5):349-360. doi: 10.1016/j.tins.2019.03.004. Epub 2019 Apr 4. Review.

PMID:
30955857
17.

Heroin addiction engages negative emotional learning brain circuits in rats.

Carmack SA, Keeley RJ, Vendruscolo JCM, Lowery-Gionta EG, Lu H, Koob GF, Stein EA, Vendruscolo LF.

J Clin Invest. 2019 Mar 26;129(6):2480-2484. doi: 10.1172/JCI125534.

18.

Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats.

de Guglielmo G, Kallupi M, Pomrenze MB, Crawford E, Simpson S, Schweitzer P, Koob GF, Messing RO, George O.

Nat Commun. 2019 Mar 18;10(1):1238. doi: 10.1038/s41467-019-09183-0.

19.

Male and female mice develop escalation of heroin intake and dependence following extended access.

Towers EB, Tunstall BJ, McCracken ML, Vendruscolo LF, Koob GF.

Neuropharmacology. 2019 Jun;151:189-194. doi: 10.1016/j.neuropharm.2019.03.019. Epub 2019 Mar 14.

PMID:
30880124
20.

Detecting neuroinflammation in the brain following chronic alcohol exposure in rats: A comparison between in vivo and in vitro TSPO radioligand binding.

Tyler RE, Kim SW, Guo M, Jang YJ, Damadzic R, Stodden T, Vendruscolo LF, Koob GF, Wang GJ, Wiers CE, Volkow ND.

Eur J Neurosci. 2019 Jul;50(1):1831-1842. doi: 10.1111/ejn.14392. Epub 2019 Mar 25.

PMID:
30803059

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