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Items: 1 to 20 of 39

1.

Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.

Leopold C, Duta-Mare M, Sachdev V, Goeritzer M, Maresch LK, Kolb D, Reicher H, Wagner B, Stojakovic T, Ruelicke T, Haemmerle G, Hoefler G, Sattler W, Kratky D.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jan 9. pii: S1388-1981(19)30004-6. doi: 10.1016/j.bbalip.2019.01.007. [Epub ahead of print]

2.

N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.

Huber K, Hofer DC, Trefely S, Pelzmann HJ, Madreiter-Sokolowski C, Duta-Mare M, Schlager S, Trausinger G, Stryeck S, Graier WF, Kolb D, Magnes C, Snyder NW, Prokesch A, Kratky D, Madl T, Wellen KE, Bogner-Strauss JG.

Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):337-348. doi: 10.1016/j.bbamcr.2018.08.017. Epub 2018 Aug 31.

3.

Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.

Duta-Mare M, Sachdev V, Leopold C, Kolb D, Vujic N, Korbelius M, Hofer DC, Xia W, Huber K, Auer M, Gottschalk B, Magnes C, Graier WF, Prokesch A, Radovic B, Bogner-Strauss JG, Kratky D.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):467-478. doi: 10.1016/j.bbalip.2018.01.011. Epub 2018 Jan 31.

4.

Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.

Schreiber R, Diwoky C, Schoiswohl G, Feiler U, Wongsiriroj N, Abdellatif M, Kolb D, Hoeks J, Kershaw EE, Sedej S, Schrauwen P, Haemmerle G, Zechner R.

Cell Metab. 2017 Nov 7;26(5):753-763.e7. doi: 10.1016/j.cmet.2017.09.004. Epub 2017 Oct 5.

5.

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.

Vujic N, Korbelius M, Leopold C, Duta-Mare M, Rainer S, Schlager S, Goeritzer M, Kolb D, Eichmann TO, Diwoky C, Zimmer A, Zimmermann R, Lass A, Radovic B, Kratky D.

Oncotarget. 2017 May 16;8(20):33122-33136. doi: 10.18632/oncotarget.16529.

6.

Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.

Hofer DC, Pessentheiner AR, Pelzmann HJ, Schlager S, Madreiter-Sokolowski CT, Kolb D, Eichmann TO, Rechberger G, Bilban M, Graier WF, Kratky D, Bogner-Strauss JG.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Mar;1862(3):358-368. doi: 10.1016/j.bbalip.2016.12.009. Epub 2016 Dec 23.

7.

Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells.

Macheiner T, Fengler VH, Agreiter M, Eisenberg T, Madeo F, Kolb D, Huppertz B, Ackbar R, Sargsyan K.

Sci Rep. 2016 Oct 21;6:35571. doi: 10.1038/srep35571.

8.

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

Grond S, Eichmann TO, Dubrac S, Kolb D, Schmuth M, Fischer J, Crumrine D, Elias PM, Haemmerle G, Zechner R, Lass A, Radner FPW.

J Invest Dermatol. 2017 Feb;137(2):394-402. doi: 10.1016/j.jid.2016.08.036. Epub 2016 Oct 14.

9.

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.

Grond S, Radner FPW, Eichmann TO, Kolb D, Grabner GF, Wolinski H, Gruber R, Hofer P, Heier C, Schauer S, Rülicke T, Hoefler G, Schmuth M, Elias PM, Lass A, Zechner R, Haemmerle G.

J Invest Dermatol. 2017 Feb;137(2):403-413. doi: 10.1016/j.jid.2016.09.025. Epub 2016 Oct 7.

10.

Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.

Sachdev V, Leopold C, Bauer R, Patankar JV, Iqbal J, Obrowsky S, Boverhof R, Doktorova M, Scheicher B, Goeritzer M, Kolb D, Turnbull AV, Zimmer A, Hoefler G, Hussain MM, Groen AK, Kratky D.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1132-1141. doi: 10.1016/j.bbalip.2016.06.014. Epub 2016 Jun 23.

11.

Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.

Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D.

Diabetologia. 2016 Aug;59(8):1743-52. doi: 10.1007/s00125-016-3968-6. Epub 2016 May 6.

12.

N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.

Prokesch A, Pelzmann HJ, Pessentheiner AR, Huber K, Madreiter-Sokolowski CT, Drougard A, Schittmayer M, Kolb D, Magnes C, Trausinger G, Graier WF, Birner-Gruenberger R, Pospisilik JA, Bogner-Strauss JG.

Sci Rep. 2016 Apr 5;6:23723. doi: 10.1038/srep23723.

13.

Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast.

Wolinski H, Hofbauer HF, Hellauer K, Cristobal-Sarramian A, Kolb D, Radulovic M, Knittelfelder OL, Rechberger GN, Kohlwein SD.

Biochim Biophys Acta. 2015 Nov;1851(11):1450-64. doi: 10.1016/j.bbalip.2015.08.003. Epub 2015 Aug 12.

14.

Phospholipid-driven differences determine the action of the synthetic antimicrobial peptide OP-145 on Gram-positive bacterial and mammalian membrane model systems.

Malanovic N, Leber R, Schmuck M, Kriechbaum M, Cordfunke RA, Drijfhout JW, de Breij A, Nibbering PH, Kolb D, Lohner K.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2437-47. doi: 10.1016/j.bbamem.2015.07.010. Epub 2015 Jul 23.

15.

Active autophagy but not lipophagy in macrophages with defective lipolysis.

Goeritzer M, Vujic N, Schlager S, Chandak PG, Korbelius M, Gottschalk B, Leopold C, Obrowsky S, Rainer S, Doddapattar P, Aflaki E, Wegscheider M, Sachdev V, Graier WF, Kolb D, Radovic B, Kratky D.

Biochim Biophys Acta. 2015 Oct;1851(10):1304-1316. doi: 10.1016/j.bbalip.2015.06.005. Epub 2015 Jul 2.

16.

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.

Schlager S, Goeritzer M, Jandl K, Frei R, Vujic N, Kolb D, Strohmaier H, Dorow J, Eichmann TO, Rosenberger A, Wölfler A, Lass A, Kershaw EE, Ceglarek U, Dichlberger A, Heinemann A, Kratky D.

J Leukoc Biol. 2015 Nov;98(5):837-50. doi: 10.1189/jlb.3A0515-206R. Epub 2015 Jun 24.

17.

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.

Jaeger D, Schoiswohl G, Hofer P, Schreiber R, Schweiger M, Eichmann TO, Pollak NM, Poecher N, Grabner GF, Zierler KA, Eder S, Kolb D, Radner FP, Preiss-Landl K, Lass A, Zechner R, Kershaw EE, Haemmerle G.

J Hepatol. 2015 Aug;63(2):437-45. doi: 10.1016/j.jhep.2015.02.035. Epub 2015 Feb 27.

18.

Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast.

Siwetz M, Sundl M, Kolb D, Hiden U, Herse F, Huppertz B, Gauster M.

Histochem Cell Biol. 2015 Jun;143(6):565-74. doi: 10.1007/s00418-014-1304-0. Epub 2015 Jan 8.

19.

Extended ultrastructural characterization of chordoma cells: the link to new therapeutic options.

Kolb D, Pritz E, Steinecker-Frohnwieser B, Lohberger B, Deutsch A, Kroneis T, El-Heliebi A, Dohr G, Meditz K, Wagner K, Koefeler H, Leitinger G, Leithner A, Liegl-Atzwanger B, Zweytick D, Rinner B.

PLoS One. 2014 Dec 5;9(12):e114251. doi: 10.1371/journal.pone.0114251. eCollection 2014.

20.

Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.

Goeritzer M, Schlager S, Radovic B, Madreiter CT, Rainer S, Thomas G, Lord CC, Sacks J, Brown AL, Vujic N, Obrowsky S, Sachdev V, Kolb D, Chandak PG, Graier WF, Sattler W, Brown JM, Kratky D.

J Lipid Res. 2014 Dec;55(12):2562-75. doi: 10.1194/jlr.M052613. Epub 2014 Oct 14.

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