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Items: 1 to 20 of 153

1.

Emerging roles for the relaxin/RXFP1 system in cancer therapy.

Thanasupawat T, Glogowska A, Nivedita-Krishnan S, Wilson B, Klonisch T, Hombach-Klonisch S.

Mol Cell Endocrinol. 2019 Feb 11. pii: S0303-7207(19)30039-5. doi: 10.1016/j.mce.2019.02.001. [Epub ahead of print] Review.

PMID:
30763603
2.

Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies.

Blanchard AA, Ma X, Wang N, Hombach-Klonisch S, Penner C, Ozturk A, Klonisch T, Pitz M, Murphy L, Leygue E, Myal Y.

Transl Oncol. 2019 Mar;12(3):561-575. doi: 10.1016/j.tranon.2018.12.011. Epub 2019 Jan 15.

3.

A radial microfluidic platform for higher throughput chemotaxis studies with individual gradient control.

Wu J, Kumar-Kanojia A, Hombach-Klonisch S, Klonisch T, Lin F.

Lab Chip. 2018 Dec 4;18(24):3855-3864. doi: 10.1039/c8lc00981c.

PMID:
30427358
4.

Statins: a new approach to combat temozolomide chemoresistance in glioblastoma.

Shojaei S, Alizadeh J, Thliveris J, Koleini N, Kardami E, Hatch GM, Xu F, Hombach-Klonisch S, Klonisch T, Ghavami S.

J Investig Med. 2018 Dec;66(8):1083-1087. doi: 10.1136/jim-2018-000874. Epub 2018 Oct 27.

PMID:
30368483
5.

Maternal smoking and high BMI disrupt thyroid gland development.

Filis P, Hombach-Klonisch S, Ayotte P, Nagrath N, Soffientini U, Klonisch T, O'Shaughnessy P, Fowler PA.

BMC Med. 2018 Oct 23;16(1):194. doi: 10.1186/s12916-018-1183-7.

6.

HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells.

Hombach-Klonisch S, Kalantari F, Medapati MR, Natarajan S, Krishnan SN, Kumar-Kanojia A, Thanasupawat T, Begum F, Xu FY, Hatch GM, Los M, Klonisch T.

Mol Oncol. 2019 Feb;13(2):153-170. doi: 10.1002/1878-0261.12390. Epub 2018 Nov 28.

7.

Inhibitor of DNA Binding 2 Inhibits Epithelial-Mesenchymal Transition via Up-Regulation of Notch3 in Breast Cancer.

Wen XF, Chen M, Wu Y, Chen MN, Glogowska A, Klonisch T, Zhang GJ.

Transl Oncol. 2018 Oct;11(5):1259-1270. doi: 10.1016/j.tranon.2018.07.015. Epub 2018 Aug 14.

8.

C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma.

Thanasupawat T, Glogowska A, Burg M, Krcek J, Beiko J, Pitz M, Zhang GJ, Hombach-Klonisch S, Klonisch T.

Mol Oncol. 2018 Sep;12(9):1464-1479. doi: 10.1002/1878-0261.12349. Epub 2018 Aug 2.

9.

Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells.

Alizadeh J, Glogowska A, Thliveris J, Kalantari F, Shojaei S, Hombach-Klonisch S, Klonisch T, Ghavami S.

Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):749-768. doi: 10.1016/j.bbamcr.2018.02.007. Epub 2018 Feb 24.

PMID:
29481833
10.

Simple, Hackable, Size-Selective, Amine-Functionalized Fe-Oxide Nanoparticles for Biomedical Applications.

Manna PK, Nickel R, Wroczynskyj Y, Yathindranath V, Li J, Liu S, Thliveris JA, Klonisch T, Miller DW, van Lierop J.

Langmuir. 2018 Feb 27;34(8):2748-2757. doi: 10.1021/acs.langmuir.7b02822. Epub 2018 Feb 12.

PMID:
29376382
11.

Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites.

Ilic A, Lu S, Bhatia V, Begum F, Klonisch T, Agarwal P, Xu W, Davie JR.

Epigenetics Chromatin. 2017 Nov 10;10(1):54. doi: 10.1186/s13072-017-0160-2.

12.

Autophagy activation is required for influenza A virus-induced apoptosis and replication.

Yeganeh B, Ghavami S, Rahim MN, Klonisch T, Halayko AJ, Coombs KM.

Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):364-378. doi: 10.1016/j.bbamcr.2017.10.014. Epub 2017 Nov 3.

13.

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response.

Hombach-Klonisch S, Mehrpour M, Shojaei S, Harlos C, Pitz M, Hamai A, Siemianowicz K, Likus W, Wiechec E, Toyota BD, Hoshyar R, Seyfoori A, Sepehri Z, Ande SR, Khadem F, Akbari M, Gorman AM, Samali A, Klonisch T, Ghavami S.

Pharmacol Ther. 2018 Apr;184:13-41. doi: 10.1016/j.pharmthera.2017.10.017. Epub 2017 Nov 8. Review.

PMID:
29080702
14.

Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts.

Ghavami S, Yeganeh B, Zeki AA, Shojaei S, Kenyon NJ, Ott S, Samali A, Patterson J, Alizadeh J, Moghadam AR, Dixon IMC, Unruh H, Knight DA, Post M, Klonisch T, Halayko AJ.

Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L493-L504. doi: 10.1152/ajplung.00372.2017. Epub 2017 Oct 26.

PMID:
29074489
15.

Characterization of GPCRs in extracellular vesicle (EV).

Medapati MR, Singh A, Korupally RR, Henderson D, Klonisch T, Manda SV, Chelikani P.

Methods Cell Biol. 2017;142:119-132. doi: 10.1016/bs.mcb.2017.07.004. Epub 2017 Sep 11.

PMID:
28964331
16.

C1q/TNF-related protein 6 (CTRP6) links obesity to adipose tissue inflammation and insulin resistance.

Lei X, Seldin MM, Little HC, Choy N, Klonisch T, Wong GW.

J Biol Chem. 2017 Sep 8;292(36):14836-14850. doi: 10.1074/jbc.M116.766808. Epub 2017 Jul 18.

17.

Dovitinib enhances temozolomide efficacy in glioblastoma cells.

Thanasupawat T, Natarajan S, Rommel A, Glogowska A, Bergen H, Krcek J, Pitz M, Beiko J, Krawitz S, Verma IM, Ghavami S, Klonisch T, Hombach-Klonisch S.

Mol Oncol. 2017 Aug;11(8):1078-1098. doi: 10.1002/1878-0261.12076. Epub 2017 Jun 5.

18.

Corrigendum to "Epidermal Growth Factor Cytoplasmic Domain Affects ErbB Protein Degradation by the Lysosomal and Ubiquitin-Proteasome Pathway in Human Cancer Cells" [Neoplasia 14 (2012) 396-409].

Glogowska A, Stetefeld J, Weber E, Ghavami S, Hoang-Vu C, Klonisch T.

Neoplasia. 2017 Apr;19(4):383. doi: 10.1016/j.neo.2017.01.009. No abstract available.

19.

New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets.

Mokarram P, Albokashy M, Zarghooni M, Moosavi MA, Sepehri Z, Chen QM, Hudecki A, Sargazi A, Alizadeh J, Moghadam AR, Hashemi M, Movassagh H, Klonisch T, Owji AA, Łos MJ, Ghavami S.

Autophagy. 2017 May 4;13(5):781-819. doi: 10.1080/15548627.2017.1290751. Epub 2017 Feb 23. Review.

20.

Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.

Alizadeh J, Zeki AA, Mirzaei N, Tewary S, Rezaei Moghadam A, Glogowska A, Nagakannan P, Eftekharpour E, Wiechec E, Gordon JW, Xu FY, Field JT, Yoneda KY, Kenyon NJ, Hashemi M, Hatch GM, Hombach-Klonisch S, Klonisch T, Ghavami S.

Sci Rep. 2017 Mar 27;7:44841. doi: 10.1038/srep44841.

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