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Items: 1 to 20 of 132


Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage.

Beyhoff N, Lohr D, Foryst-Ludwig A, Klopfleisch R, Brix S, Grune J, Thiele A, Erfinanda L, Tabuchi A, Kuebler WM, Pieske B, Schreiber LM, Kintscher U.

Hypertension. 2019 Aug;74(2):295-304. doi: 10.1161/HYPERTENSIONAHA.119.12956. Epub 2019 Jul 10.


Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction.

Grune J, Ritter D, Kräker K, Pappritz K, Beyhoff N, Schütte T, Ott C, John C, van Linthout S, Tschöpe C, Dechend R, Muller DN, Haase N, Grune T, Kintscher U, Kuebler WM.

Cardiovasc Ultrasound. 2019 Apr 22;17(1):7. doi: 10.1186/s12947-019-0156-0.


2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.

Regitz-Zagrosek V, Roos-Hesselink JW, Bauersachs J, Blomstrom-Lundqvist C, Cifkova R, De Bonis M, Iung B, Johnson MR, Kintscher U, Kranke P, Lang IM, Morais J, Pieper PG, Presbitero P, Price S, Rosano GMC, Seeland U, Simoncini T, Swan L, Warnes CA.

Kardiol Pol. 2019;77(3):245-326. doi: 10.5603/KP.2019.0049. No abstract available.


Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse.

John C, Grune J, Ott C, Nowotny K, Deubel S, Kühne A, Schubert C, Kintscher U, Regitz-Zagrosek V, Grune T.

Front Endocrinol (Lausanne). 2018 Dec 4;9:732. doi: 10.3389/fendo.2018.00732. eCollection 2018.


Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome.

Merz J, Albrecht P, von Garlen S, Ahmed I, Dimanski D, Wolf D, Hilgendorf I, Härdtner C, Grotius K, Willecke F, Heidt T, Bugger H, Hoppe N, Kintscher U, von Zur Mühlen C, Idzko M, Bode C, Zirlik A, Stachon P.

Basic Res Cardiol. 2018 Oct 18;113(6):45. doi: 10.1007/s00395-018-0702-1.


2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.

Regitz-Zagrosek V, Roos-Hesselink JW, Bauersachs J, Blomström-Lundqvist C, Cífková R, De Bonis M, Iung B, Johnson MR, Kintscher U, Kranke P, Lang IM, Morais J, Pieper PG, Presbitero P, Price S, Rosano GMC, Seeland U, Simoncini T, Swan L, Warnes CA; ESC Scientific Document Group .

Eur Heart J. 2018 Sep 7;39(34):3165-3241. doi: 10.1093/eurheartj/ehy340. No abstract available.


AT2R (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat.

Lange C, Sommerfeld M, Namsolleck P, Kintscher U, Unger T, Kaschina E.

Hypertension. 2018 Sep;72(3):e20-e29. doi: 10.1161/HYPERTENSIONAHA.118.11168.


Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals.

Grune J, Blumrich A, Brix S, Jeuthe S, Drescher C, Grune T, Foryst-Ludwig A, Messroghli D, Kuebler WM, Ott C, Kintscher U.

Cardiovasc Ultrasound. 2018 Jul 3;16(1):10. doi: 10.1186/s12947-018-0128-9.


The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics.

Gertz K, Uhlemann R, Foryst-Ludwig A, Barrientos RM, Kappert K, Thöne-Reineke C, Djoufack P, Kirschbaum C, Fink KB, Heinz A, Kintscher U, Endres M, Kronenberg G.

Exp Neurol. 2018 Aug;306:34-44. doi: 10.1016/j.expneurol.2018.04.004. Epub 2018 Apr 21.


Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity.

Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, Brix S, Betz IR, Schupp M, Foryst-Ludwig A, Klopfleisch R, Stawowy P, Houtman R, Kolkhof P, Kintscher U.

Hypertension. 2018 Apr;71(4):599-608. doi: 10.1161/HYPERTENSIONAHA.117.10360. Epub 2018 Feb 5.


Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.

Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Muhlen C, von Elverfeldt D, Pfeifer D, Schüle R, Kintscher U, Brachs S, Ley K, Bode C, Zirlik A, Wolf D.

Circ Res. 2018 Mar 2;122(5):693-700. doi: 10.1161/CIRCRESAHA.117.312055. Epub 2018 Jan 22.


Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.

Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U.

PLoS Genet. 2018 Jan 10;14(1):e1007171. doi: 10.1371/journal.pgen.1007171. eCollection 2018 Jan.


Application of Speckle-Tracking Echocardiography in an Experimental Model of Isolated Subendocardial Damage.

Beyhoff N, Brix S, Betz IR, Klopfleisch R, Foryst-Ludwig A, Krannich A, Stawowy P, Knebel F, Grune J, Kintscher U.

J Am Soc Echocardiogr. 2017 Dec;30(12):1239-1250.e2. doi: 10.1016/j.echo.2017.08.006. Epub 2017 Oct 21.


Expression of matrix metalloproteinase-11 is increased under conditions of insulin resistance.

Arcidiacono B, Chiefari E, Laria AE, Messineo S, Bilotta FL, Britti D, Foti DP, Foryst-Ludwig A, Kintscher U, Brunetti A.

World J Diabetes. 2017 Sep 15;8(9):422-428. doi: 10.4239/wjd.v8.i9.422.


Cardiovascular magnetic resonance feature tracking in small animals - a preliminary study on reproducibility and sample size calculation.

Lapinskas T, Grune J, Zamani SM, Jeuthe S, Messroghli D, Gebker R, Meyborg H, Kintscher U, Zaliunas R, Pieske B, Stawowy P, Kelle S.

BMC Med Imaging. 2017 Aug 23;17(1):51. doi: 10.1186/s12880-017-0223-7.


AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice.

Krueger F, Kappert K, Foryst-Ludwig A, Kramer F, Clemenz M, Grzesiak A, Sommerfeld M, Paul Frese J, Greiner A, Kintscher U, Unger T, Kaschina E.

Clin Sci (Lond). 2017 Jul 13;131(15):1989-2005. doi: 10.1042/CS20170131. Print 2017 Aug 1.


High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha.

Ban Z, Maurischat P, Benz V, Brix S, Sonnenburg A, Schuler G, Klopfleisch R, Rothe M, Gustafsson JÅ, Foryst-Ludwig A, Kintscher U.

Sci Rep. 2017 Feb 24;7:43269. doi: 10.1038/srep43269.


PCSK9 regulates the chemokine receptor CCR2 on monocytes.

Grune J, Meyborg H, Bezhaeva T, Kappert K, Hillmeister P, Kintscher U, Pieske B, Stawowy P.

Biochem Biophys Res Commun. 2017 Apr 1;485(2):312-318. doi: 10.1016/j.bbrc.2017.02.085. Epub 2017 Feb 20.


Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPARγ agonists.

Obermoser V, Mauersberger R, Schuster D, Czifersky M, Lipova M, Siegl M, Kintscher U, Gust R.

Eur J Med Chem. 2017 Jan 27;126:590-603. doi: 10.1016/j.ejmech.2016.11.051. Epub 2016 Nov 25.


New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile.

Obermoser V, Urban ME, Murgueitio MS, Wolber G, Kintscher U, Gust R.

Eur J Med Chem. 2016 Nov 29;124:138-152. doi: 10.1016/j.ejmech.2016.08.027. Epub 2016 Aug 15.


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