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Items: 1 to 20 of 415

1.

Myocardial Phosphodiesterases and their Role in cGMP Regulation.

Dunkerly-Eyring B, Kass DA.

J Cardiovasc Pharmacol. 2019 Oct 21. doi: 10.1097/FJC.0000000000000773. [Epub ahead of print]

PMID:
31651671
2.

Large Particle Fluorescence-Activated Cell Sorting Enables High-Quality Single-Cell RNA Sequencing and Functional Analysis of Adult Cardiomyocytes.

Kannan S, Miyamoto M, Lin BL, Zhu R, Murphy S, Kass DA, Andersen P, Kwon C.

Circ Res. 2019 Aug 16;125(5):567-569. doi: 10.1161/CIRCRESAHA.119.315493. Epub 2019 Aug 15. No abstract available.

PMID:
31415233
3.

Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway.

Yousefi K, Irion CI, Takeuchi LM, Ding W, Lambert G, Eisenberg T, Sukkar S, Granzier HL, Methawasin M, Lee DI, Hahn VS, Kass DA, Hatzistergos KE, Hare JM, Webster KA, Shehadeh LA.

J Am Coll Cardiol. 2019 Jun 4;73(21):2705-2718. doi: 10.1016/j.jacc.2019.02.074.

PMID:
31146816
4.

Leveraging Signaling Pathways to Treat Heart Failure With Reduced Ejection Fraction.

Pinilla-Vera M, Hahn VS, Kass DA.

Circ Res. 2019 May 24;124(11):1618-1632. doi: 10.1161/CIRCRESAHA.119.313682.

PMID:
31120818
5.

Response by Kass et al to Letter Regarding Article, "Chronic Atrial and Ventricular Pacing in the Mouse: Application to Model Cardiac Dyssynchrony and Resynchronization in Heart Failure".

Kass DA, Nakagawa R, Ståhlberg M.

Circ Heart Fail. 2019 May;12(5):e006094. doi: 10.1161/CIRCHEARTFAILURE.119.006094. No abstract available.

PMID:
31079489
6.

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.

Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161. doi: 10.1073/pnas.1815354116. Epub 2019 Apr 26.

7.

Nitrosative stress drives heart failure with preserved ejection fraction.

Schiattarella GG, Altamirano F, Tong D, French KM, Villalobos E, Kim SY, Luo X, Jiang N, May HI, Wang ZV, Hill TM, Mammen PPA, Huang J, Lee DI, Hahn VS, Sharma K, Kass DA, Lavandero S, Gillette TG, Hill JA.

Nature. 2019 Apr;568(7752):351-356. doi: 10.1038/s41586-019-1100-z. Epub 2019 Apr 10.

8.

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.

Barefield DY, McNamara JW, Lynch TL, Kuster DWD, Govindan S, Haar L, Wang Y, Taylor EN, Lorenz JN, Nieman ML, Zhu G, Luther PK, Varró A, Dobrev D, Ai X, Janssen PML, Kass DA, Jones WK, Gilbert RJ, Sadayappan S.

J Mol Cell Cardiol. 2019 Apr;129:236-246. doi: 10.1016/j.yjmcc.2019.03.006. Epub 2019 Mar 9.

9.

Fresh evidence overturns the identification of a factor involved in blood-vessel dilation.

Kass DA.

Nature. 2019 Feb;566(7745):462-464. doi: 10.1038/d41586-019-00508-z. No abstract available.

PMID:
30809049
10.

Chronic Atrial and Ventricular Pacing in the Mouse.

Ståhlberg M, Nakagawa R, Bedja D, Zhu G, Lin BL, Saberi A, Lee DI, Kass DA.

Circ Heart Fail. 2019 Feb;12(2):e005655. doi: 10.1161/CIRCHEARTFAILURE.118.005655.

PMID:
30764638
11.

PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.

Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, Kass DA.

Nature. 2019 Feb;566(7743):264-269. doi: 10.1038/s41586-019-0895-y. Epub 2019 Jan 30.

12.

Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis.

Zhang QJ, Tran TAT, Wang M, Ranek MJ, Kokkonen-Simon KM, Gao J, Luo X, Tan W, Kyrychenko V, Liao L, Xu J, Hill JA, Olson EN, Kass DA, Martinez ED, Liu ZP.

Nat Commun. 2018 Dec 7;9(1):5230. doi: 10.1038/s41467-018-07173-2.

13.

Randomized Evaluation of Heart Failure With Preserved Ejection Fraction Patients With Acute Heart Failure and Dopamine: The ROPA-DOP Trial.

Sharma K, Vaishnav J, Kalathiya R, Hu JR, Miller J, Shah N, Hill T, Sharp M, Tsao A, Alexander KM, Gupta R, Montemayor K, Kovell L, Chasler JE, Lee YJ, Fine DM, Kass DA, Weiss RG, Thiemann DR, Ndumele CE, Schulman SP, Russell SD; Osler Medical Housestaff.

JACC Heart Fail. 2018 Oct;6(10):859-870. doi: 10.1016/j.jchf.2018.04.008. Epub 2018 Aug 8.

14.

Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease.

Kokkonen-Simon KM, Saberi A, Nakamura T, Ranek MJ, Zhu G, Bedja D, Kuhn M, Halushka MK, Lee DI, Kass DA.

JCI Insight. 2018 Aug 9;3(15). pii: 121739. doi: 10.1172/jci.insight.121739. eCollection 2018 Aug 9.

15.

Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition.

Hashimoto T, Kim GE, Tunin RS, Adesiyun T, Hsu S, Nakagawa R, Zhu G, O'Brien JJ, Hendrick JP, Davis RE, Yao W, Beard D, Hoxie HR, Wennogle LP, Lee DI, Kass DA.

Circulation. 2018 Oct 30;138(18):1974-1987. doi: 10.1161/CIRCULATIONAHA.117.030490.

16.

Pulmonary Effective Arterial Elastance as a Measure of Right Ventricular Afterload and Its Prognostic Value in Pulmonary Hypertension Due to Left Heart Disease.

Tampakakis E, Shah SJ, Borlaug BA, Leary PJ, Patel HH, Miller WL, Kelemen BW, Houston BA, Kolb TM, Damico R, Mathai SC, Kasper EK, Hassoun PM, Kass DA, Tedford RJ.

Circ Heart Fail. 2018 Apr;11(4):e004436. doi: 10.1161/CIRCHEARTFAILURE.117.004436.

17.

Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State.

Wang SB, Venkatraman V, Crowgey EL, Liu T, Fu Z, Holewinski R, Ranek M, Kass DA, O'Rourke B, Van Eyk JE.

Circ Res. 2018 May 25;122(11):1517-1531. doi: 10.1161/CIRCRESAHA.118.312789. Epub 2018 Mar 21.

18.

Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation.

Nakamura T, Zhu G, Ranek MJ, Kokkonen-Simon K, Zhang M, Kim GE, Tsujita K, Kass DA.

Circ Heart Fail. 2018 Mar;11(3):e004740. doi: 10.1161/CIRCHEARTFAILURE.117.004740.

19.

Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension.

Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.

Circulation. 2018 May 29;137(22):2360-2370. doi: 10.1161/CIRCULATIONAHA.117.033147. Epub 2018 Jan 19.

20.

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy.

Chung HS, Kim GE, Holewinski RJ, Venkatraman V, Zhu G, Bedja D, Kass DA, Van Eyk JE.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10763-E10771. doi: 10.1073/pnas.1712623114. Epub 2017 Nov 29.

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