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Page 1
The structural basis for cohesin-CTCF-anchored loops.
Li Y, Haarhuis JHI, Sedeño Cacciatore Á, Oldenkamp R, van Ruiten MS, Willems L, Teunissen H, Muir KW, de Wit E, Rowland BD, Panne D. Li Y, et al. Among authors: haarhuis jhi. Nature. 2020 Feb;578(7795):472-476. doi: 10.1038/s41586-019-1910-z. Epub 2020 Jan 6. Nature. 2020. PMID: 31905366 Free PMC article.
The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.
van Ruiten MS, van Gent D, Sedeño Cacciatore Á, Fauster A, Willems L, Hekkelman ML, Hoekman L, Altelaar M, Haarhuis JHI, Brummelkamp TR, de Wit E, Rowland BD. van Ruiten MS, et al. Among authors: haarhuis jhi. Nat Struct Mol Biol. 2022 Jun;29(6):586-591. doi: 10.1038/s41594-022-00773-z. Epub 2022 Jun 16. Nat Struct Mol Biol. 2022. PMID: 35710836 Free PMC article.
A Mediator-cohesin axis controls heterochromatin domain formation.
Haarhuis JHI, van der Weide RH, Blomen VA, Flach KD, Teunissen H, Willems L, Brummelkamp TR, Rowland BD, de Wit E. Haarhuis JHI, et al. Nat Commun. 2022 Feb 8;13(1):754. doi: 10.1038/s41467-022-28377-7. Nat Commun. 2022. PMID: 35136067 Free PMC article.
The histone methyltransferase SETD2 negatively regulates cell size.
Molenaar TM, Malik M, Silva J, Liu NQ, Haarhuis JHI, Ambrosi C, Kwesi-Maliepaard EM, van Welsem T, Baubec T, Faller WJ, van Leeuwen F. Molenaar TM, et al. Among authors: haarhuis jhi. J Cell Sci. 2022 Oct 1;135(19):jcs259856. doi: 10.1242/jcs.259856. Epub 2022 Oct 6. J Cell Sci. 2022. PMID: 36052643 Free PMC article.
Cohesin: building loops, but not compartments.
Haarhuis JH, Rowland BD. Haarhuis JH, et al. EMBO J. 2017 Dec 15;36(24):3549-3551. doi: 10.15252/embj.201798654. Epub 2017 Dec 7. EMBO J. 2017. PMID: 29217589 Free PMC article.
Enhancer hubs and loop collisions identified from single-allele topologies.
Allahyar A, Vermeulen C, Bouwman BAM, Krijger PHL, Verstegen MJAM, Geeven G, van Kranenburg M, Pieterse M, Straver R, Haarhuis JHI, Jalink K, Teunissen H, Renkens IJ, Kloosterman WP, Rowland BD, de Wit E, de Ridder J, de Laat W. Allahyar A, et al. Among authors: haarhuis jhi. Nat Genet. 2018 Aug;50(8):1151-1160. doi: 10.1038/s41588-018-0161-5. Epub 2018 Jul 9. Nat Genet. 2018. PMID: 29988121
Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.
Elbatsh AMO, Haarhuis JHI, Petela N, Chapard C, Fish A, Celie PH, Stadnik M, Ristic D, Wyman C, Medema RH, Nasmyth K, Rowland BD. Elbatsh AMO, et al. Among authors: haarhuis jhi. Mol Cell. 2016 Feb 18;61(4):575-588. doi: 10.1016/j.molcel.2016.01.025. Mol Cell. 2016. PMID: 26895426 Free PMC article.
Hi-C analyses with GENOVA: a case study with cohesin variants.
van der Weide RH, van den Brand T, Haarhuis JHI, Teunissen H, Rowland BD, de Wit E. van der Weide RH, et al. Among authors: haarhuis jhi. NAR Genom Bioinform. 2021 May 22;3(2):lqab040. doi: 10.1093/nargab/lqab040. eCollection 2021 Jun. NAR Genom Bioinform. 2021. PMID: 34046591 Free PMC article.
14 results