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Items: 1 to 20 of 30


Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets.

Zhang F, Kang Y, Wang M, Li Y, Xu T, Yang W, Song H, Wu H, Shu Q, Jin P.

Hum Mol Genet. 2018 Nov 15;27(22):3936-3950. doi: 10.1093/hmg/ddy292.


Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures.

Myrick LK, Deng PY, Hashimoto H, Oh YM, Cho Y, Poidevin MJ, Suhl JA, Visootsak J, Cavalli V, Jin P, Cheng X, Warren ST, Klyachko VA.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):949-56. doi: 10.1073/pnas.1423094112. Epub 2015 Jan 5.


A feed-forward mechanism involving Drosophila fragile X mental retardation protein triggers a replication stress-induced DNA damage response.

Zhang W, Cheng Y, Li Y, Chen Z, Jin P, Chen D.

Hum Mol Genet. 2014 Oct 1;23(19):5188-96. doi: 10.1093/hmg/ddu241. Epub 2014 May 15.


Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.

Wang T, Pan Q, Lin L, Szulwach KE, Song CX, He C, Wu H, Warren ST, Jin P, Duan R, Li X.

Hum Mol Genet. 2012 Dec 15;21(26):5500-10. doi: 10.1093/hmg/dds394. Epub 2012 Oct 5.


Fragile X premutation RNA is sufficient to cause primary ovarian insufficiency in mice.

Lu C, Lin L, Tan H, Wu H, Sherman SL, Gao F, Jin P, Chen D.

Hum Mol Genet. 2012 Dec 1;21(23):5039-47. doi: 10.1093/hmg/dds348. Epub 2012 Aug 21.


Circadian rhythm-dependent alterations of gene expression in Drosophila brain lacking fragile X mental retardation protein.

Xu S, Poidevin M, Han E, Bi J, Jin P.

PLoS One. 2012;7(5):e37937. doi: 10.1371/journal.pone.0037937. Epub 2012 May 24.


RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome.

Li Y, Jin P.

Brain Res. 2012 Jun 26;1462:112-7. doi: 10.1016/j.brainres.2012.02.057. Epub 2012 Mar 9. Review.


Fragile X mental retardation protein and stem cells.

Qurashi A, Li X, Jin P.

Results Probl Cell Differ. 2012;54:157-64. doi: 10.1007/978-3-642-21649-7_8.


Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats.

Qurashi A, Li W, Zhou JY, Peng J, Jin P.

PLoS Genet. 2011 Jun;7(6):e1002102. doi: 10.1371/journal.pgen.1002102. Epub 2011 Jun 2.


Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells.

Luo Y, Shan G, Guo W, Smrt RD, Johnson EB, Li X, Pfeiffer RL, Szulwach KE, Duan R, Barkho BZ, Li W, Liu C, Jin P, Zhao X.

PLoS Genet. 2010 Apr 8;6(4):e1000898. doi: 10.1371/journal.pgen.1000898.


Macro role(s) of microRNAs in fragile X syndrome?

Li X, Jin P.

Neuromolecular Med. 2009;11(3):200-7. doi: 10.1007/s12017-009-8081-2. Epub 2009 Aug 11. Review.


RNA-mediated pathogenesis in fragile X-associated disorders.

Tan H, Li H, Jin P.

Neurosci Lett. 2009 Dec 4;466(2):103-8. doi: 10.1016/j.neulet.2009.07.053. Epub 2009 Jul 23. Review.


The bantam microRNA is associated with drosophila fragile X mental retardation protein and regulates the fate of germline stem cells.

Yang Y, Xu S, Xia L, Wang J, Wen S, Jin P, Chen D.

PLoS Genet. 2009 Apr;5(4):e1000444. doi: 10.1371/journal.pgen.1000444. Epub 2009 Apr 3.


The microRNA pathway and fragile X mental retardation protein.

Li Y, Lin L, Jin P.

Biochim Biophys Acta. 2008 Nov;1779(11):702-5. doi: 10.1016/j.bbagrm.2008.07.003. Epub 2008 Jul 18. Review.


Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila.

Chang S, Bray SM, Li Z, Zarnescu DC, He C, Jin P, Warren ST.

Nat Chem Biol. 2008 Apr;4(4):256-63. doi: 10.1038/nchembio.78. Epub 2008 Mar 9.


FXTAS: a bad RNA and a hope for a cure.

Shan G, Xu S, Jin P.

Expert Opin Biol Ther. 2008 Mar;8(3):249-53. doi: 10.1517/14712598.8.3.249 . Review.


Epigenetics and Neural developmental disorders: Washington DC, September 18 and 19, 2006.

Zhao X, Pak C, Smrt RD, Jin P.

Epigenetics. 2007 Apr-Jun;2(2):126-34. Epub 2007 Apr 30.


RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS.

Sofola OA, Jin P, Qin Y, Duan R, Liu H, de Haro M, Nelson DL, Botas J.

Neuron. 2007 Aug 16;55(4):565-71.


Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome.

Jin P, Duan R, Qurashi A, Qin Y, Tian D, Rosser TC, Liu H, Feng Y, Warren ST.

Neuron. 2007 Aug 16;55(4):556-64.


Argonaute-2-dependent rescue of a Drosophila model of FXTAS by FRAXE premutation repeat.

Sofola OA, Jin P, Botas J, Nelson DL.

Hum Mol Genet. 2007 Oct 1;16(19):2326-32. Epub 2007 Jul 17.


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