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Items: 5


A Proposed Roadmap for Parkinson's Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein.

Merchant KM, Cedarbaum JM, Brundin P, Dave KD, Eberling J, Espay AJ, Hutten SJ, Javidnia M, Luthman J, Maetzler W, Menalled L, Reimer AN, Stoessl AJ, Weiner DM; and The Michael J. Fox Foundation Alpha Synuclein Clinical Path Working Group.

J Parkinsons Dis. 2019;9(1):31-61. doi: 10.3233/JPD-181471.


Tau clearance improves astrocytic function and brain glutamate-glutamine cycle.

Hebron ML, Javidnia M, Moussa CE.

J Neurol Sci. 2018 Aug 15;391:90-99. doi: 10.1016/j.jns.2018.06.005. Epub 2018 Jun 12.


Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy.

Javidnia M, Hebron ML, Xin Y, Kinney NG, Moussa CE.

J Alzheimers Dis. 2017;60(2):461-481. doi: 10.3233/JAD-170429.


Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors.

DiRaddo JO, Miller EJ, Bowman-Dalley C, Wroblewska B, Javidnia M, Grajkowska E, Wolfe BB, Liotta DC, Wroblewski JT.

Mol Pharmacol. 2015 Sep;88(3):450-9. doi: 10.1124/mol.114.096420. Epub 2015 Jun 18.


Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.

Kokkinaki M, Abu-Asab M, Gunawardena N, Ahern G, Javidnia M, Young J, Golestaneh N.

J Neurosci. 2013 Oct 9;33(41):16346-59. doi: 10.1523/JNEUROSCI.0402-13.2013. Erratum in: J Neurosci. 2016 Jun 15;36(24):6597.

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