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Items: 1 to 20 of 41

1.

Isolation of synaptic vesicles from genetically engineered cultured neurons.

McKenzie C, Spanova M, Johnson A, Kainrath S, Zheden V, Sitte HH, Janovjak H.

J Neurosci Methods. 2018 Nov 26;312:114-121. doi: 10.1016/j.jneumeth.2018.11.018. [Epub ahead of print]

PMID:
30496761
2.

Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS.

Zhang WH, Herde MK, Mitchell JA, Whitfield JH, Wulff AB, Vongsouthi V, Sanchez-Romero I, Gulakova PE, Minge D, Breithausen B, Schoch S, Janovjak H, Jackson CJ, Henneberger C.

Nat Chem Biol. 2018 Sep;14(9):861-869. doi: 10.1038/s41589-018-0108-2. Epub 2018 Jul 30.

PMID:
30061718
3.

Optical functionalization of human Class A orphan G-protein-coupled receptors.

Morri M, Sanchez-Romero I, Tichy AM, Kainrath S, Gerrard EJ, Hirschfeld PP, Schwarz J, Janovjak H.

Nat Commun. 2018 May 16;9(1):1950. doi: 10.1038/s41467-018-04342-1.

4.

Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains.

Kainrath S, Stadler M, Reichhart E, Distel M, Janovjak H.

Angew Chem Int Ed Engl. 2017 Apr 10;56(16):4608-4611. doi: 10.1002/anie.201611998. Epub 2017 Mar 20.

5.

Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment.

Mitchell JA, Zhang WH, Herde MK, Henneberger C, Janovjak H, O'Mara ML, Jackson CJ.

Methods Mol Biol. 2017;1596:89-99. doi: 10.1007/978-1-4939-6940-1_6.

PMID:
28293882
6.

Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors.

Clifton BE, Whitfield JH, Sanchez-Romero I, Herde MK, Henneberger C, Janovjak H, Jackson CJ.

Methods Mol Biol. 2017;1596:71-87. doi: 10.1007/978-1-4939-6940-1_5.

PMID:
28293881
7.

Optogenetic methods in drug screening: technologies and applications.

Agus V, Janovjak H.

Curr Opin Biotechnol. 2017 Dec;48:8-14. doi: 10.1016/j.copbio.2017.02.006. Epub 2017 Mar 6. Review.

PMID:
28273648
8.

Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.

Sako K, Pradhan SJ, Barone V, Inglés-Prieto Á, Müller P, Ruprecht V, Čapek D, Galande S, Janovjak H, Heisenberg CP.

Cell Rep. 2016 Jul 19;16(3):866-77. doi: 10.1016/j.celrep.2016.06.036. Epub 2016 Jul 7.

9.

A Phytochrome Sensory Domain Permits Receptor Activation by Red Light.

Reichhart E, Ingles-Prieto A, Tichy AM, McKenzie C, Janovjak H.

Angew Chem Int Ed Engl. 2016 May 17;55(21):6339-42. doi: 10.1002/anie.201601736. Epub 2016 Apr 21.

PMID:
27101018
10.

Light at the End of the Protein: Crystal Structure of a C-Terminal Light-Sensing Domain.

Janovjak H.

Structure. 2016 Feb 2;24(2):213-5. doi: 10.1016/j.str.2016.01.002.

11.

Light-assisted small-molecule screening against protein kinases.

Inglés-Prieto Á, Reichhart E, Muellner MK, Nowak M, Nijman SM, Grusch M, Janovjak H.

Nat Chem Biol. 2015 Dec;11(12):952-4. doi: 10.1038/nchembio.1933. Epub 2015 Oct 12.

12.

Flipping the Photoswitch: Ion Channels Under Light Control.

McKenzie CK, Sanchez-Romero I, Janovjak H.

Adv Exp Med Biol. 2015;869:101-17. doi: 10.1007/978-1-4939-2845-3_6. Review.

PMID:
26381942
13.

Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction.

Whitfield JH, Zhang WH, Herde MK, Clifton BE, Radziejewski J, Janovjak H, Henneberger C, Jackson CJ.

Protein Sci. 2015 Sep;24(9):1412-22. doi: 10.1002/pro.2721. Epub 2015 Aug 18.

14.

Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection.

Hühner J, Ingles-Prieto Á, Neusüß C, Lämmerhofer M, Janovjak H.

Electrophoresis. 2015 Feb;36(4):518-25. doi: 10.1002/elps.201400451. Epub 2015 Jan 22.

PMID:
25488801
15.

The optogenetic promise for oncology: Episode I.

Ingles-Prieto A, Reichhart E, Schelch K, Janovjak H, Grusch M.

Mol Cell Oncol. 2014 Oct 29;1(4):e964045. doi: 10.4161/23723548.2014.964045. eCollection 2014 Oct-Dec.

16.

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

Grusch M, Schelch K, Riedler R, Reichhart E, Differ C, Berger W, Inglés-Prieto Á, Janovjak H.

EMBO J. 2014 Aug 1;33(15):1713-26. doi: 10.15252/embj.201387695. Epub 2014 Jul 1.

17.

Optical control of ligand-gated ion channels.

Szobota S, McKenzie C, Janovjak H.

Methods Mol Biol. 2013;998:417-35. doi: 10.1007/978-1-62703-351-0_32.

PMID:
23529448
18.

Optical control of metabotropic glutamate receptors.

Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY.

Nat Neurosci. 2013 Apr;16(4):507-16. doi: 10.1038/nn.3346. Epub 2013 Mar 3.

19.

A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence.

Janovjak H, Sandoz G, Isacoff EY.

Nat Commun. 2011;2:232. doi: 10.1038/ncomms1231.

PMID:
21407198
20.

Pharmacology of ionotropic glutamate receptors: A structural perspective.

Stawski P, Janovjak H, Trauner D.

Bioorg Med Chem. 2010 Nov 15;18(22):7759-72. doi: 10.1016/j.bmc.2010.09.012. Epub 2010 Sep 19. Review.

PMID:
20947363

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