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Items: 1 to 20 of 61

1.

Six2 mediates late-stage metastasis via direct regulation of Sox2 and induction of a cancer stem cell program.

Oliphant MUJ, Vincent MY, Galbraith MD, Pandey A, Zaberezhnyy V, Rudra P, Johnson KR, Costello JC, Ghosh D, DeGregori J, Espinosa JM, Ford HL.

Cancer Res. 2019 Jan 3. pii: canres.1791.2018. doi: 10.1158/0008-5472.CAN-18-1791. [Epub ahead of print]

PMID:
30606720
2.

A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer.

Goodspeed A, Jean A, Costello JC.

Eur Urol. 2018 Nov 7. pii: S0302-2838(18)30835-2. doi: 10.1016/j.eururo.2018.10.040. [Epub ahead of print]

PMID:
30414698
3.

Metastatic cells are preferentially vulnerable to lysosomal inhibition.

Morgan MJ, Fitzwalter BE, Owens CR, Powers RK, Sottnik JL, Gamez G, Costello JC, Theodorescu D, Thorburn A.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8479-E8488. doi: 10.1073/pnas.1706526115. Epub 2018 Aug 20.

PMID:
30127018
4.

A Gene Expression Signature Predicts Bladder Cancer Cell Line Sensitivity to EGFR Inhibition.

Goodspeed A, Jean A, Theodorescu D, Costello JC.

Bladder Cancer. 2018 Jul 30;4(3):269-282. doi: 10.3233/BLC-170161.

5.

GSEA-InContext: identifying novel and common patterns in expression experiments.

Powers RK, Goodspeed A, Pielke-Lombardo H, Tan AC, Costello JC.

Bioinformatics. 2018 Jul 1;34(13):i555-i564. doi: 10.1093/bioinformatics/bty271.

6.

Next-Generation Machine Learning for Biological Networks.

Camacho DM, Collins KM, Powers RK, Costello JC, Collins JJ.

Cell. 2018 Jun 14;173(7):1581-1592. doi: 10.1016/j.cell.2018.05.015. Epub 2018 Jun 7. Review.

PMID:
29887378
7.

Simulating heterogeneous populations using Boolean models.

Ross BC, Boguslav M, Weeks H, Costello JC.

BMC Syst Biol. 2018 Jun 7;12(1):64. doi: 10.1186/s12918-018-0591-9.

8.

Eya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulation.

Vartuli RL, Zhou H, Zhang L, Powers RK, Klarquist J, Rudra P, Vincent MY, Ghosh D, Costello JC, Kedl RM, Slansky JE, Zhao R, Ford HL.

J Clin Invest. 2018 Jun 1;128(6):2535-2550. doi: 10.1172/JCI96784. Epub 2018 May 14.

9.

Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines.

Zuiverloon TCM, de Jong FC, Costello JC, Theodorescu D.

Bladder Cancer. 2018 Apr 26;4(2):169-183. doi: 10.3233/BLC-180167.

10.

Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.

Stern JL, Paucek RD, Huang FW, Ghandi M, Nwumeh R, Costello JC, Cech TR.

Cell Rep. 2017 Dec 26;21(13):3700-3707. doi: 10.1016/j.celrep.2017.12.001.

11.

Community mining of open clinical trial data.

Laajala TD, Guinney J, Costello JC.

Oncotarget. 2017 Sep 13;8(47):81721-81722. doi: 10.18632/oncotarget.20853. eCollection 2017 Oct 10. No abstract available.

12.

Contrast Agents for MR Imaging.

Czeyda-Pommersheim F, Martin DR, Costello JR, Kalb B.

Magn Reson Imaging Clin N Am. 2017 Nov;25(4):705-711. doi: 10.1016/j.mric.2017.06.011. Review.

PMID:
28964460
13.

All Paths Lead to TRIM25.

Zhou H, Costello JC.

Trends Cancer. 2017 Oct;3(10):673-675. doi: 10.1016/j.trecan.2017.08.005.

PMID:
28958384
14.

MRI in pelvic inflammatory disease: a pictorial review.

Czeyda-Pommersheim F, Kalb B, Costello J, Liau J, Meshksar A, Arif Tiwari H, Martin D.

Abdom Radiol (NY). 2017 Mar;42(3):935-950. doi: 10.1007/s00261-016-1004-4. Review.

PMID:
27933478
15.

A SPATIOTEMPORAL MODEL TO SIMULATE CHEMOTHERAPY REGIMENS FOR HETEROGENEOUS BLADDER CANCER METASTASES TO THE LUNG.

Kanigel Winner KR, Costello JC.

Pac Symp Biocomput. 2017;22:611-622. doi: 10.1142/9789813207813_0056.

16.

Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data.

Guinney J, Wang T, Laajala TD, Winner KK, Bare JC, Neto EC, Khan SA, Peddinti G, Airola A, Pahikkala T, Mirtti T, Yu T, Bot BM, Shen L, Abdallah K, Norman T, Friend S, Stolovitzky G, Soule H, Sweeney CJ, Ryan CJ, Scher HI, Sartor O, Xie Y, Aittokallio T, Zhou FL, Costello JC; Prostate Cancer Challenge DREAM Community.

Lancet Oncol. 2017 Jan;18(1):132-142. doi: 10.1016/S1470-2045(16)30560-5. Epub 2016 Nov 16.

17.

MRI of ovarian torsion: Correlation of imaging features with the presence of perifollicular hemorrhage and ovarian viability.

Petkovska I, Duke E, Martin DR, Irani Z, Geffre CP, Cragun JM, Costello JR, Arif-Tiwari H, Czeyda-Pommersheim F, Udayasankar U, Kalb B.

Eur J Radiol. 2016 Nov;85(11):2064-2071. doi: 10.1016/j.ejrad.2016.09.020. Epub 2016 Sep 23.

PMID:
27776660
18.

Incidence and Risk Factors for Gadolinium-Based Contrast Agent Immediate Reactions.

Costello JR, Kalb B, Martin DR.

Top Magn Reson Imaging. 2016 Dec;25(6):257-263. Review.

PMID:
27748714
19.

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.

Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG.

Cell Rep. 2016 Sep 20;16(12):3195-3207. doi: 10.1016/j.celrep.2016.08.050.

20.

The hydrolysis of geminal ethers: a kinetic appraisal of orthoesters and ketals.

Repetto SL, Costello JF, Butts CP, Lam JK, Ratcliffe NM.

Beilstein J Org Chem. 2016 Jul 15;12:1467-75. doi: 10.3762/bjoc.12.143. eCollection 2016.

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