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Items: 1 to 20 of 29

1.

A case of subepidermal autoimmune bullous disease with autoantibodies against 200 and 290-kDa antigens.

Sawada M, Hida T, Ujiie H, Iwata H, Uhara H.

J Eur Acad Dermatol Venereol. 2018 Mar 10. doi: 10.1111/jdv.14927. [Epub ahead of print] No abstract available.

PMID:
29524251
2.

Association analysis identifies 65 new breast cancer risk loci.

Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang Z, Allen J, Keeman R, Eilber U, French JD, Qing Chen X, Fachal L, McCue K, McCart Reed AE, Ghoussaini M, Carroll JS, Jiang X, Finucane H, Adams M, Adank MA, Ahsan H, Aittomäki K, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Arun B, Auer PL, Bacot F, Barrdahl M, Baynes C, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Bogdanova NV, Bojesen SE, Bonanni B, Børresen-Dale AL, Brand JS, Brauch H, Brennan P, Brenner H, Brinton L, Broberg P, Brock IW, Broeks A, Brooks-Wilson A, Brucker SY, Brüning T, Burwinkel B, Butterbach K, Cai Q, Cai H, Caldés T, Canzian F, Carracedo A, Carter BD, Castelao JE, Chan TL, David Cheng TY, Seng Chia K, Choi JY, Christiansen H, Clarke CL; NBCS Collaborators, Collée M, Conroy DM, Cordina-Duverger E, Cornelissen S, Cox DG, Cox A, Cross SS, Cunningham JM, Czene K, Daly MB, Devilee P, Doheny KF, Dörk T, Dos-Santos-Silva I, Dumont M, Durcan L, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Elvira M, Engel C, Eriksson M, Fasching PA, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Fritschi L, Gaborieau V, Gabrielson M, Gago-Dominguez M, Gao YT, Gapstur SM, García-Sáenz JA, Gaudet MM, Georgoulias V, Giles GG, Glendon G, Goldberg MS, Goldgar DE, González-Neira A, Grenaker Alnæs GI, Grip M, Gronwald J, Grundy A, Guénel P, Haeberle L, Hahnen E, Haiman CA, Håkansson N, Hamann U, Hamel N, Hankinson S, Harrington P, Hart SN, Hartikainen JM, Hartman M, Hein A, Heyworth J, Hicks B, Hillemanns P, Ho DN, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Hou MF, Hsiung CN, Huang G, Humphreys K, Ishiguro J, Ito H, Iwasaki M, Iwata H, Jakubowska A, Janni W, John EM, Johnson N, Jones K, Jones M, Jukkola-Vuorinen A, Kaaks R, Kabisch M, Kaczmarek K, Kang D, Kasuga Y, Kerin MJ, Khan S, Khusnutdinova E, Kiiski JI, Kim SW, Knight JA, Kosma VM, Kristensen VN, Krüger U, Kwong A, Lambrechts D, Le Marchand L, Lee E, Lee MH, Lee JW, Neng Lee C, Lejbkowicz F, Li J, Lilyquist J, Lindblom A, Lissowska J, Lo WY, Loibl S, Long J, Lophatananon A, Lubinski J, Luccarini C, Lux MP, Ma ESK, MacInnis RJ, Maishman T, Makalic E, Malone KE, Kostovska IM, Mannermaa A, Manoukian S, Manson JE, Margolin S, Mariapun S, Martinez ME, Matsuo K, Mavroudis D, McKay J, McLean C, Meijers-Heijboer H, Meindl A, Menéndez P, Menon U, Meyer J, Miao H, Miller N, Taib NAM, Muir K, Mulligan AM, Mulot C, Neuhausen SL, Nevanlinna H, Neven P, Nielsen SF, Noh DY, Nordestgaard BG, Norman A, Olopade OI, Olson JE, Olsson H, Olswold C, Orr N, Pankratz VS, Park SK, Park-Simon TW, Lloyd R, Perez JIA, Peterlongo P, Peto J, Phillips KA, Pinchev M, Plaseska-Karanfilska D, Prentice R, Presneau N, Prokofyeva D, Pugh E, Pylkäs K, Rack B, Radice P, Rahman N, Rennert G, Rennert HS, Rhenius V, Romero A, Romm J, Ruddy KJ, Rüdiger T, Rudolph A, Ruebner M, Rutgers EJT, Saloustros E, Sandler DP, Sangrajrang S, Sawyer EJ, Schmidt DF, Schmutzler RK, Schneeweiss A, Schoemaker MJ, Schumacher F, Schürmann P, Scott RJ, Scott C, Seal S, Seynaeve C, Shah M, Sharma P, Shen CY, Sheng G, Sherman ME, Shrubsole MJ, Shu XO, Smeets A, Sohn C, Southey MC, Spinelli JJ, Stegmaier C, Stewart-Brown S, Stone J, Stram DO, Surowy H, Swerdlow A, Tamimi R, Taylor JA, Tengström M, Teo SH, Beth Terry M, Tessier DC, Thanasitthichai S, Thöne K, Tollenaar RAEM, Tomlinson I, Tong L, Torres D, Truong T, Tseng CC, Tsugane S, Ulmer HU, Ursin G, Untch M, Vachon C, van Asperen CJ, Van Den Berg D, van den Ouweland AMW, van der Kolk L, van der Luijt RB, Vincent D, Vollenweider J, Waisfisz Q, Wang-Gohrke S, Weinberg CR, Wendt C, Whittemore AS, Wildiers H, Willett W, Winqvist R, Wolk A, Wu AH, Xia L, Yamaji T, Yang XR, Har Yip C, Yoo KY, Yu JC, Zheng W, Zheng Y, Zhu B, Ziogas A, Ziv E; ABCTB Investigators; ConFab/AOCS Investigators, Lakhani SR, Antoniou AC, Droit A, Andrulis IL, Amos CI, Couch FJ, Pharoah PDP, Chang-Claude J, Hall P, Hunter DJ, Milne RL, García-Closas M, Schmidt MK, Chanock SJ, Dunning AM, Edwards SL, Bader GD, Chenevix-Trench G, Simard J, Kraft P, Easton DF.

Nature. 2017 Nov 2;551(7678):92-94. doi: 10.1038/nature24284. Epub 2017 Oct 23.

3.

In vivo enzymatic modulation of IgG antibodies prevents immune complex-dependent skin injury.

Mihai S, Albert H, Ludwig RJ, Iwata H, Björck L, Collin M, Nimmerjahn F.

Exp Dermatol. 2017 Aug;26(8):691-696. doi: 10.1111/exd.13163. Epub 2016 Dec 15.

PMID:
27512946
4.

Cutaneous B-cell Pseudolymphoma in a Psoriatic Patient Treated with Cyclosporine.

Takahashi T, Hata M, Iwata H, Seishima M.

Acta Derm Venereol. 2016 Aug 23;96(6):824-5. doi: 10.2340/00015555-2387. No abstract available.

5.

Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita.

Iwata H, Witte M, Samavedam UK, Gupta Y, Shimizu A, Ishiko A, Schröder T, Seeger K, Dahlke M, Rades D, Zillikens D, Ludwig RJ.

J Immunol. 2015 Sep 1;195(5):1945-54. doi: 10.4049/jimmunol.1501003. Epub 2015 Jul 22.

6.

Prevalence of pemphigus and pemphigoid autoantibodies in the general population.

Prüßmann W, Prüßmann J, Koga H, Recke A, Iwata H, Juhl D, Görg S, Henschler R, Hashimoto T, Schmidt E, Zillikens D, Ibrahim SM, Ludwig RJ.

Orphanet J Rare Dis. 2015 May 15;10:63. doi: 10.1186/s13023-015-0278-x.

7.

Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules.

Sadeghi H, Lockmann A, Hund AC, Samavedam UK, Pipi E, Vafia K, Hauenschild E, Kalies K, Pas HH, Jonkman MF, Iwata H, Recke A, Schön MP, Zillikens D, Schmidt E, Ludwig RJ.

J Immunol. 2015 Apr 15;194(8):3656-63. doi: 10.4049/jimmunol.1402688. Epub 2015 Mar 20.

8.

Animal models to investigate pathomechanisms and evaluate novel treatments for autoimmune bullous dermatoses.

Iwata H, Bieber K, Hirose M, Ludwig RJ.

Curr Pharm Des. 2015;21(18):2422-39. Review.

PMID:
25777758
9.

Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters.

Vorobyev A, Ujiie H, Recke A, Buijsrogge JJA, Jonkman MF, Pas HH, Iwata H, Hashimoto T, Kim SC, Hoon Kim J, Groves R, Samavedam U, Gupta Y, Schmidt E, Zillikens D, Shimizu H, Ludwig RJ.

J Invest Dermatol. 2015 Jun;135(6):1565-1573. doi: 10.1038/jid.2015.51. Epub 2015 Feb 17.

10.

Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita.

Iwata H, Pipi E, Möckel N, Sondermann P, Vorobyev A, van Beek N, Zillikens D, Ludwig RJ.

J Invest Dermatol. 2015 Mar;135(3):916-919. doi: 10.1038/jid.2014.451. Epub 2014 Oct 20. No abstract available.

11.

Persistent autoantibody-production by intermediates between short-and long-lived plasma cells in inflamed lymph nodes of experimental epidermolysis bullosa acquisita.

Tiburzy B, Szyska M, Iwata H, Chrobok N, Kulkarni U, Hirose M, Ludwig RJ, Kalies K, Westermann J, Wong D, Manz RA.

PLoS One. 2013 Dec 26;8(12):e83631. doi: 10.1371/journal.pone.0083631. eCollection 2013.

12.

Flightless I over-expression impairs skin barrier development, function and recovery following skin blistering.

Kopecki Z, Yang GN, Arkell RM, Jackson JE, Melville E, Iwata H, Ludwig RJ, Zillikens D, Murrell DF, Cowin AJ.

J Pathol. 2014 Apr;232(5):541-52. doi: 10.1002/path.4323. Epub 2014 Feb 5.

PMID:
24375017
13.

GM-CSF modulates autoantibody production and skin blistering in experimental epidermolysis bullosa acquisita.

Samavedam UK, Iwata H, Müller S, Schulze FS, Recke A, Schmidt E, Zillikens D, Ludwig RJ.

J Immunol. 2014 Jan 15;192(2):559-71. doi: 10.4049/jimmunol.1301556. Epub 2013 Dec 11.

14.

B cells, dendritic cells, and macrophages are required to induce an autoreactive CD4 helper T cell response in experimental epidermolysis bullosa acquisita.

Iwata H, Bieber K, Tiburzy B, Chrobok N, Kalies K, Shimizu A, Leineweber S, Ishiko A, Vorobyev A, Zillikens D, Köhl J, Westermann J, Seeger K, Manz R, Ludwig RJ.

J Immunol. 2013 Sep 15;191(6):2978-88. doi: 10.4049/jimmunol.1300310. Epub 2013 Aug 19.

15.

Bullous pemphigoid: role of complement and mechanisms for blister formation within the lamina lucida.

Iwata H, Kitajima Y.

Exp Dermatol. 2013 Jun;22(6):381-5. doi: 10.1111/exd.12146. Epub 2013 May 7. Review.

PMID:
23651418
16.

Topically applied flightless I neutralizing antibodies improve healing of blistered skin in a murine model of epidermolysis bullosa acquisita.

Kopecki Z, Ruzehaji N, Turner C, Iwata H, Ludwig RJ, Zillikens D, Murrell DF, Cowin AJ.

J Invest Dermatol. 2013 Apr;133(4):1008-16. doi: 10.1038/jid.2012.457. Epub 2012 Dec 6.

17.

Overexpression of monocyte chemoattractant protein-1 in the overlying epidermis of multicentric reticulohistiocytosis lesions: a case report.

Iwata H, Okumura Y, Seishima M, Aoyama Y.

Int J Dermatol. 2012 Apr;51(4):492-4. doi: 10.1111/j.1365-4632.2010.04573.x. No abstract available.

PMID:
22435444
18.

Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury.

Kasperkiewicz M, Nimmerjahn F, Wende S, Hirose M, Iwata H, Jonkman MF, Samavedam U, Gupta Y, Möller S, Rentz E, Hellberg L, Kalies K, Yu X, Schmidt E, Häsler R, Laskay T, Westermann J, Köhl J, Zillikens D, Ludwig RJ.

J Pathol. 2012 Sep;228(1):8-19. doi: 10.1002/path.4023. Epub 2012 May 8.

PMID:
22430937
19.

Characterization of NLRP3 variants in Japanese cryopyrin-associated periodic syndrome patients.

Ohnishi H, Teramoto T, Iwata H, Kato Z, Kimura T, Kubota K, Nishikomori R, Kaneko H, Seishima M, Kondo N.

J Clin Immunol. 2012 Apr;32(2):221-9. doi: 10.1007/s10875-011-9629-0. Epub 2011 Dec 24.

PMID:
22193915
20.

Three siblings with systemic lupus erythematosus.

Shu E, Ichiki Y, Moriya C, Iwata H, Kitajima Y, Seishima M.

J Dermatol. 2012 Feb;39(2):164-7. doi: 10.1111/j.1346-8138.2011.01333.x. Epub 2011 Dec 2.

PMID:
22132698

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