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Year Number of Results
1983 3
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1985 10
1986 21
1987 8
1988 24
1989 12
1990 13
1991 15
1992 8
1993 7
1994 19
1995 16
1996 9
1997 9
1998 11
1999 6
2000 8
2001 17
2002 17
2003 17
2004 22
2005 41
2006 21
2007 46
2008 39
2009 54
2010 49
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2012 65
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2015 78
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1,330 results

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The following term was not found in PubMed: 2Bschizophrenia
Page 1
Platelet-derived extracellular vesicles inhibit ferroptosis and promote distant metastasis of nasopharyngeal carcinoma by upregulating ITGB3.
Li F, Xu T, Chen P, Sun R, Li C, Zhao X, Ou J, Li J, Liu T, Zeng M, Zheng W, Lin Y, Yang L, Li Z, Chen H, Zhang Q. Li F, et al. Int J Biol Sci. 2022 Sep 24;18(15):5858-5872. doi: 10.7150/ijbs.76162. eCollection 2022. Int J Biol Sci. 2022. PMID: 36263165 Free PMC article.
Here we found that the distant metastasis of NPC patients was positively correlated with the expression levels of integrin beta3 (ITGB3) in platelet-derived extracellular vesicles (EVs) from NPC patients (P-EVs). We further revealed that EVs transfer occurred from platelet …
Here we found that the distant metastasis of NPC patients was positively correlated with the expression levels of integrin beta3 (ITGB3
CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3.
Feng W, Huang W, Chen J, Qiao C, Liu D, Ji X, Xie M, Zhang T, Wang Y, Sun M, Tian D, Fan D, Nie Y, Wu K, Xia L. Feng W, et al. Theranostics. 2021 Jan 1;11(6):2612-2633. doi: 10.7150/thno.52199. eCollection 2021. Theranostics. 2021. PMID: 33456563 Free PMC article.
Overexpression of HOXB5 promoted CRC metastasis by transactivating metastatic related genes, C-X-C motif chemokine receptor 4 (CXCR4) and integrin subunit beta 3 (ITGB3). C-X-C motif chemokine ligand 12 (CXCL12), which is the ligand of CXCR4, upregulated HOXB5 expression t …
Overexpression of HOXB5 promoted CRC metastasis by transactivating metastatic related genes, C-X-C motif chemokine receptor 4 (CXCR4) and in …
ITGB3/CD61: a hub modulator and target in the tumor microenvironment.
Zhu C, Kong Z, Wang B, Cheng W, Wu A, Meng X. Zhu C, et al. Am J Transl Res. 2019 Dec 15;11(12):7195-7208. eCollection 2019. Am J Transl Res. 2019. PMID: 31934272 Free PMC article. Review.
beta3 integrin (ITGB3), also known as CD61 or GP3A, is one of the most widely studied components in the integrin family. ...Lastly, we focus on the inhibitors of ITGB3, ultimately indicating that ITGB3 is a promising target in the tumor microenvironment....
beta3 integrin (ITGB3), also known as CD61 or GP3A, is one of the most widely studied components in the integrin family. ...Lastly, w …
Single-Exosome Profiling Identifies ITGB3+ and ITGAM+ Exosome Subpopulations as Promising Early Diagnostic Biomarkers and Therapeutic Targets for Colorectal Cancer.
Guo W, Cai Y, Liu X, Ji Y, Zhang C, Wang L, Liao W, Liu Y, Cui N, Xiang J, Li Z, Wu D, Li J. Guo W, et al. Research (Wash D C). 2023;6:0041. doi: 10.34133/research.0041. Epub 2023 Jan 30. Research (Wash D C). 2023. PMID: 37040507 Free PMC article.
Twelve distinct exosome subpopulations were determined. We found 2 distinctly abundant subpopulations: one ITGB3-positive and the other ITGAM-positive. The ITGB3-positive cluster is rich in liver-metastatic CRC, compared to both HC group and primary CRC group. ...No …
Twelve distinct exosome subpopulations were determined. We found 2 distinctly abundant subpopulations: one ITGB3-positive and the oth …
ITGB3 promotes cisplatin resistance in osteosarcoma tumors.
Li Q, Chen G, Jiang H, Dai H, Li D, Zhu K, Zhang K, Shen H, Xu H, Li S. Li Q, et al. Cancer Med. 2023 Apr;12(7):8452-8463. doi: 10.1002/cam4.5585. Epub 2023 Feb 11. Cancer Med. 2023. PMID: 36772869 Free PMC article.
The expression of ITGB3 was analysis in collected human osteosarcoma tissues. In addition, the potential functions of ITGB3 in the cisplatin resistance of osteosarcoma cells were investigated in vitro and in tumor xenotransplantation. ...In addition, ITGB3 ha …
The expression of ITGB3 was analysis in collected human osteosarcoma tissues. In addition, the potential functions of ITGB3 in …
Promotion of Lung Cancer Metastasis by SIRT2-Mediated Extracellular Protein Deacetylation.
Wu M, Zhang JB, Xiong YW, Zhao YX, Zheng MG, Huang XL, Huang F, Wu XX, Li X, Fan WJ, Hu L, Zeng YY, Cheng XJ, Yue JC, Du JJ, Chen NN, Wei WX, Yao QH, Lu XM, Huang C, Deng J, Chang ZJ, Liu HB, Zhao TC, Chinn YE. Wu M, et al. Adv Sci (Weinh). 2023 Jan;10(3):e2205462. doi: 10.1002/advs.202205462. Epub 2022 Dec 1. Adv Sci (Weinh). 2023. PMID: 36453571 Free PMC article.
Here it is described that multiple acetyl-vWA domain-carrying proteins including integrin beta3 (ITGB3) and collagen 6A (COL6A) are deacetylated by Sirtuin family member SIRT2 in extracellular space. ...In lung cancer patients, significantly increased serum eSIRT2 level co …
Here it is described that multiple acetyl-vWA domain-carrying proteins including integrin beta3 (ITGB3) and collagen 6A (COL6A) are d …
lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling.
Lin X, Zhuang S, Chen X, Du J, Zhong L, Ding J, Wang L, Yi J, Hu G, Tang G, Luo X, Liu W, Ye F. Lin X, et al. Mol Ther. 2022 Feb 2;30(2):688-702. doi: 10.1016/j.ymthe.2021.08.011. Epub 2021 Aug 8. Mol Ther. 2022. PMID: 34371180 Free PMC article.
Mechanistically, ITGB8-AS1 could sponge miR-33b-5p and let-7c-5p/let-7d-5p to regulate the expression of integrin family genes ITGA3 and ITGB3, respectively, in the cytosol of cells. Targeting ITGB8-AS1 using antisense oligonucleotide (ASO) markedly reduced cell proliferat …
Mechanistically, ITGB8-AS1 could sponge miR-33b-5p and let-7c-5p/let-7d-5p to regulate the expression of integrin family genes ITGA3 and …
The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models.
Salama Y, Heida AH, Yokoyama K, Takahashi S, Hattori K, Heissig B. Salama Y, et al. Blood Adv. 2020 Mar 24;4(6):1021-1037. doi: 10.1182/bloodadvances.2019001002. Blood Adv. 2020. PMID: 32191808 Free PMC article.
MM cells both produced EGFL7 and expressed the functional EGFL7 receptor integrin beta 3 (ITGB3), resulting in ITGB3 phosphorylation and focal adhesion kinase activation. Overexpression of ITGB3 or EGFL7 enhanced MM cell adhesion and proliferation. Intriguing …
MM cells both produced EGFL7 and expressed the functional EGFL7 receptor integrin beta 3 (ITGB3), resulting in ITGB3 phosphory …
Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia.
Li D, Peng J, Li T, Liu Y, Chen M, Shi X. Li D, et al. Mol Med Rep. 2021 Jun;23(6):449. doi: 10.3892/mmr.2021.12088. Epub 2021 Apr 21. Mol Med Rep. 2021. PMID: 33880575 Free PMC article.
Itgb3-integrin-deficient (Itgb3(-/-)) mice have been reported as a Glanzmann thrombasthenia (GT) model and have been used for platelet research. ...Itgb3(-/-) mice demonstrated decreased platelet count and microcytic hypochromic anemia. ...
Itgb3-integrin-deficient (Itgb3(-/-)) mice have been reported as a Glanzmann thrombasthenia (GT) model and have been used for
1,330 results