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Items: 12

1.

Natural Peptides in Drug Discovery Targeting Acetylcholinesterase.

Prasasty V, Radifar M, Istyastono E.

Molecules. 2018 Sep 13;23(9). pii: E2344. doi: 10.3390/molecules23092344. Review.

2.

PyPLIF: Python-based Protein-Ligand Interaction Fingerprinting.

Radifar M, Yuniarti N, Istyastono EP.

Bioinformation. 2013;9(6):325-8. doi: 10.6026/97320630009325. Epub 2013 Mar 19.

3.

Structure-based design of eugenol analogs as potential estrogen receptor antagonists.

Anita Y, Radifar M, Kardono LB, Hanafi M, Istyastono EP.

Bioinformation. 2012;8(19):901-6. doi: 10.6026/97320630008901. Epub 2012 Oct 1.

4.

Virtual fragment screening: discovery of histamine H3 receptor ligands using ligand-based and protein-based molecular fingerprints.

Sirci F, Istyastono EP, Vischer HF, Kooistra AJ, Nijmeijer S, Kuijer M, Wijtmans M, Mannhold R, Leurs R, de Esch IJ, de Graaf C.

J Chem Inf Model. 2012 Dec 21;52(12):3308-24. doi: 10.1021/ci3004094. Epub 2012 Dec 3.

PMID:
23140085
5.

Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.

Istyastono EP, Nijmeijer S, Lim HD, van de Stolpe A, Roumen L, Kooistra AJ, Vischer HF, de Esch IJ, Leurs R, de Graaf C.

J Med Chem. 2011 Dec 8;54(23):8136-47. doi: 10.1021/jm201042n. Epub 2011 Nov 7.

PMID:
22003888
6.
7.

Triazole ligands reveal distinct molecular features that induce histamine H4 receptor affinity and subtly govern H4/H3 subtype selectivity.

Wijtmans M, de Graaf C, de Kloe G, Istyastono EP, Smit J, Lim H, Boonnak R, Nijmeijer S, Smits RA, Jongejan A, Zuiderveld O, de Esch IJ, Leurs R.

J Med Chem. 2011 Mar 24;54(6):1693-703. doi: 10.1021/jm1013488. Epub 2011 Feb 24.

PMID:
21348462
8.

Molecular determinants of selective agonist and antagonist binding to the histamine Hâ‚„ receptor.

Istyastono EP, de Graaf C, de Esch IJ, Leurs R.

Curr Top Med Chem. 2011;11(6):661-79. Review.

PMID:
21261593
9.

Synthesis and QSAR of quinazoline sulfonamides as highly potent human histamine H4 receptor inverse agonists.

Smits RA, Adami M, Istyastono EP, Zuiderveld OP, van Dam CM, de Kanter FJ, Jongejan A, Coruzzi G, Leurs R, de Esch IJ.

J Med Chem. 2010 Mar 25;53(6):2390-400. doi: 10.1021/jm901379s.

PMID:
20192225
10.

Molecular determinants of ligand binding to H4R species variants.

Lim HD, de Graaf C, Jiang W, Sadek P, McGovern PM, Istyastono EP, Bakker RA, de Esch IJ, Thurmond RL, Leurs R.

Mol Pharmacol. 2010 May;77(5):734-43. doi: 10.1124/mol.109.063040. Epub 2010 Jan 26.

11.

Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.

Lim HD, Istyastono EP, van de Stolpe A, Romeo G, Gobbi S, Schepers M, Lahaye R, Menge WM, Zuiderveld OP, Jongejan A, Smits RA, Bakker RA, Haaksma EE, Leurs R, de Esch IJ.

Bioorg Med Chem. 2009 Jun 1;17(11):3987-94. doi: 10.1016/j.bmc.2009.04.007. Epub 2009 Apr 11.

PMID:
19414267
12.

Inhibition of human glutathione S-transferases by curcumin and analogues.

Appiah-Opong R, Commandeur JN, Istyastono E, Bogaards JJ, Vermeulen NP.

Xenobiotica. 2009 Apr;39(4):302-11. doi: 10.1080/00498250802702316.

PMID:
19350453

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