Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 4
1947 4
1948 1
1949 3
1950 3
1951 19
1952 10
1953 8
1954 2
1955 2
1958 1
1959 2
1960 1
1962 1
1963 3
1964 7
1965 4
1967 2
1968 4
1969 2
1970 1
1971 2
1972 1
1973 3
1974 7
1975 3
1976 2
1977 2
1978 2
1979 3
1980 2
1981 7
1982 19
1983 9
1984 13
1985 10
1986 12
1987 20
1988 17
1989 17
1990 12
1991 11
1992 14
1993 7
1994 9
1995 10
1996 14
1997 10
1998 14
1999 16
2000 25
2001 13
2002 28
2003 38
2004 45
2005 36
2006 47
2007 60
2008 74
2009 76
2010 54
2011 53
2012 52
2013 55
2014 46
2015 50
2016 36
2017 26
2018 23
2019 18
2020 20
2021 12
2022 16
2023 16
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

1,187 results

Results by year

Filters applied: . Clear all
Page 1
Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus.
Horvath K, Jeitler K, Berghold A, Ebrahim SH, Gratzer TW, Plank J, Kaiser T, Pieber TR, Siebenhofer A. Horvath K, et al. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD005613. doi: 10.1002/14651858.CD005613.pub3. Cochrane Database Syst Rev. 2007. PMID: 17443605 Free article. Updated. Review.
OBJECTIVES: To assess the effects of long-term treatment with long-acting insulin analogues (insulin glargine and insulin detemir) compared to NPH insulin in patients with type 2 diabetes mellitus. ...Pooling of studies by means of random-effects meta- …
OBJECTIVES: To assess the effects of long-term treatment with long-acting insulin analogues (insulin glargine and insulin …
A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review.
Frier BM, Russell-Jones D, Heise T. Frier BM, et al. Diabetes Obes Metab. 2013 Nov;15(11):978-86. doi: 10.1111/dom.12106. Epub 2013 May 1. Diabetes Obes Metab. 2013. PMID: 23551900 Review.
The aim of this review is to summarize the clinical efficacy, tolerability and safety data of insulin detemir, and compare its use with that of neutral protamine Hagedorn (NPH) insulin in randomized controlled trials in people with type 1 or type 2 diabetes. ...Stud …
The aim of this review is to summarize the clinical efficacy, tolerability and safety data of insulin detemir, and compare its use wi …
Absorption of isophane (NPH) insulin and its clinical implications.
Lauritzen T, Pramming S, Gale EA, Deckert T, Binder C. Lauritzen T, et al. Br Med J (Clin Res Ed). 1982 Jul 17;285(6336):159-62. doi: 10.1136/bmj.285.6336.159. Br Med J (Clin Res Ed). 1982. PMID: 6807390 Free PMC article.
Absorption of 125I-NPH insulin (125I-isophane insulin) (40 IU/ml) was studied in eight diabetics given 50% and 150% of their normal daily dose of insulin. ...Changes in dise of intermediate-acting insulin further increases the large variation in …
Absorption of 125I-NPH insulin (125I-isophane insulin) (40 IU/ml) was studied in eight diabetics given 50% and 150% of …
Human isophane or lente insulin? A double blind crossover trial in insulin dependent diabetes mellitus.
Gibb DM, Foot AB, May B, Parish H, Strang S, Grant DB, Dunger DB. Gibb DM, et al. Arch Dis Child. 1990 Dec;65(12):1334-7. doi: 10.1136/adc.65.12.1334. Arch Dis Child. 1990. PMID: 2270941 Free PMC article. Clinical Trial.
Fifty two children with insulin dependent diabetes mellitus were randomised to receive human isophane or lente insulin preparations in combination with soluble insulin in a double blind trial. ...In five children on twice daily insulin regimens, …
Fifty two children with insulin dependent diabetes mellitus were randomised to receive human isophane or lente insulin …
A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine.
Belhekar MN, Pai S, Tayade P, Dalwadi P, Munshi R, Varthakavi P. Belhekar MN, et al. Indian J Pharmacol. 2015 Mar-Apr;47(2):227-9. doi: 10.4103/0253-7613.153438. Indian J Pharmacol. 2015. PMID: 25878390 Free PMC article.
Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. ...Here, we present a case of Type 2 DM who demonstrated immediate (Type 1) hypersensitivity reaction on the sites of subcu …
Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatmen …
Exercise augments the absorption of isophane (NPH) insulin.
Thow JC, Johnson AB, Antsiferov M, Home PD. Thow JC, et al. Diabet Med. 1989 May-Jun;6(4):342-5. doi: 10.1111/j.1464-5491.1989.tb01177.x. Diabet Med. 1989. PMID: 2524341
In order to determine the effect of exercise on the rate of absorption of an isophane (NPH) insulin, 7 normal men were studied on two separate occasions using the euglycaemic clamp technique. ...These results demonstrate an enhanced rate of absorption of an isoph …
In order to determine the effect of exercise on the rate of absorption of an isophane (NPH) insulin, 7 normal men were studied …
Chronic urticaria from isophane insulin therapy; sensitivity associated with noninsulin components in commercial preparations.
Shore RN, Shelley WB, Kyle GC. Shore RN, et al. Arch Dermatol. 1975 Jan;111(1):94-7. Arch Dermatol. 1975. PMID: 1119830
A young woman with diabetes mellitus developed chronic urticaria after changing from isophane been insulin suspension to isophane beef-pork insulin suspension. ...Zinc single-peak beef insulin suspension, a purer preparation with different addit …
A young woman with diabetes mellitus developed chronic urticaria after changing from isophane been insulin suspension to is …
[Action profile of a semisynthetic human isophane zinc insulin compared with customary isophane insulin].
Gin H, Delafaye C, Morlat P, Aubertin J. Gin H, et al. Diabete Metab. 1992 Nov-Dec;18(6):445-50. Diabete Metab. 1992. PMID: 1297601 French.
Addition of zinc to a protamine-isophane insulin should probably allow to lengthen its duration of action. Therefore we compared the action of this new type of insulin (NPH Zn) with that of a classical protamine-isophane NPH insulin (NPH); both …
Addition of zinc to a protamine-isophane insulin should probably allow to lengthen its duration of action. Therefore we compar …
Morning versus bedtime isophane insulin in type 2 (non-insulin dependent) diabetes mellitus.
Seigler DE, Olsson GM, Skyler JS. Seigler DE, et al. Diabet Med. 1992 Nov;9(9):826-33. doi: 10.1111/j.1464-5491.1992.tb01901.x. Diabet Med. 1992. PMID: 1473323 Clinical Trial.
Mean (+/- SEM) daily total insulin dosage was equivalent for the morning (0.36 +/- 0.03 units kg-1) and for the bedtime (0.37 +/- 0.03 units kg-1) insulin administration schedules. Glycaemic control was improved on both insulin regimens, but was better on bed …
Mean (+/- SEM) daily total insulin dosage was equivalent for the morning (0.36 +/- 0.03 units kg-1) and for the bedtime (0.37 +/- 0.0 …
1,187 results