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Items: 1 to 20 of 29


Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2.

Weiswald LB, Hasan MR, Wong JCT, Pasiliao CC, Rahman M, Ren J, Yin Y, Gusscott S, Vacher S, Weng AP, Kennecke HF, Bièche I, Schaeffer DF, Yapp DT, Tai IT.

Mol Cancer Ther. 2017 Oct;16(10):2292-2303. doi: 10.1158/1535-7163.MCT-16-0666. Epub 2017 Jun 29.


Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment.

Hosseini-Beheshti E, Choi W, Weiswald LB, Kharmate G, Ghaffari M, Roshan-Moniri M, Hassona MD, Chan L, Chin MY, Tai IT, Rennie PS, Fazli L, Tomlinson Guns ES.

Oncotarget. 2016 Mar 22;7(12):14639-58. doi: 10.18632/oncotarget.7052.


Disposable sheath that facilitates endoscopic Raman spectroscopy.

Wang W, Short M, Tai IT, Zeng H.

J Biomed Opt. 2016 Feb;21(2):25001. doi: 10.1117/1.JBO.21.2.025001.


Development and in vivo testing of a high frequency endoscopic Raman spectroscopy system for potential applications in the detection of early colonic neoplasia.

Short MA, Wang W, Tai IT, Zeng H.

J Biophotonics. 2016 Jan;9(1-2):44-8. doi: 10.1002/jbio.201500205. Epub 2015 Nov 20.


Label-free surface-enhanced Raman spectroscopy for detection of colorectal cancer and precursor lesions using blood plasma.

Feng S, Wang W, Tai IT, Chen G, Chen R, Zeng H.

Biomed Opt Express. 2015 Aug 24;6(9):3494-502. doi: 10.1364/BOE.6.003494. eCollection 2015 Sep 1.


Correction: A Peptide of SPARC Interferes with the Interaction between Caspase8 and Bcl2 to Resensitize Chemoresistant Tumors and Enhance Their Regression In Vivo.

Rahman M, Chan AP, Tang MJ, Tai IT.

PLoS One. 2015 Apr 23;10(4):e0127226. doi: 10.1371/journal.pone.0127226. eCollection 2015. No abstract available.


Irinophore C™, a lipid nanoparticulate formulation of irinotecan, improves vascular function, increases the delivery of sequentially administered 5-FU in HT-29 tumors, and controls tumor growth in patient derived xenografts of colon cancer.

Neijzen R, Wong MQ, Gill N, Wang H, Karim T, Anantha M, Strutt D, Waterhouse D, Bally MB, Tai IT, Ng SS, Yapp DT.

J Control Release. 2015 Feb 10;199:72-83. doi: 10.1016/j.jconrel.2014.11.031. Epub 2014 Dec 8.


Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence.

Wong JC, Hasan MR, Rahman M, Yu AC, Chan SK, Schaeffer DF, Kennecke HF, Lim HJ, Owen D, Tai IT.

Int J Cancer. 2013 Oct 1;133(7):1567-77. doi: 10.1002/ijc.28180. Epub 2013 Apr 30.


Using high frequency Raman spectra for colonic neoplasia detection.

Short MA, Tai IT, Owen D, Zeng H.

Opt Express. 2013 Feb 25;21(4):5025-34. doi: 10.1364/OE.21.005025.


A handheld electromagnetically actuated fiber optic raster scanner for reflectance confocal imaging of biological tissues.

Mansoor H, Zeng H, Tai IT, Zhao J, Chiao M.

IEEE Trans Biomed Eng. 2013 May;60(5):1431-8. doi: 10.1109/TBME.2012.2236326. Epub 2012 Dec 31.


Inhibition of COX-2 in colon cancer modulates tumor growth and MDR-1 expression to enhance tumor regression in therapy-refractory cancers in vivo.

Rahman M, Selvarajan K, Hasan MR, Chan AP, Jin C, Kim J, Chan SK, Le ND, Kim YB, Tai IT.

Neoplasia. 2012 Jul;14(7):624-33.


Helicobacter pylori in First Nations and recent immigrant populations in Canada.

Jones N, Chiba N, Fallone C, Thompson A, Hunt R, Jacobson K, Goodman K; Canadian Helicobacter Study Group Participants.

Can J Gastroenterol. 2012 Feb;26(2):97-103. Review.


A peptide of SPARC interferes with the interaction between caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivo.

Rahman M, Chan AP, Tang M, Tai IT.

PLoS One. 2011;6(11):e26390. doi: 10.1371/journal.pone.0026390. Epub 2011 Nov 1. Erratum in: PLoS One. 2015;10(4):e0127226.


Inhibition of VEGF induces cellular senescence in colorectal cancer cells.

Hasan MR, Ho SH, Owen DA, Tai IT.

Int J Cancer. 2011 Nov 1;129(9):2115-23. doi: 10.1002/ijc.26179. Epub 2011 Aug 3.


Absence of MMP2 expression correlates with poor clinical outcomes in rectal cancer, and is distinct from MMP1-related outcomes in colon cancer.

Wong JC, Chan SK, Schaeffer DF, Sagaert X, Lim HJ, Kennecke H, Owen DA, Suh KW, Kim YB, Tai IT.

Clin Cancer Res. 2011 Jun 15;17(12):4167-76. doi: 10.1158/1078-0432.CCR-10-1224. Epub 2011 Apr 29.


Alternative expression analysis by RNA sequencing.

Griffith M, Griffith OL, Mwenifumbo J, Goya R, Morrissy AS, Morin RD, Corbett R, Tang MJ, Hou YC, Pugh TJ, Robertson G, Chittaranjan S, Ally A, Asano JK, Chan SY, Li HI, McDonald H, Teague K, Zhao Y, Zeng T, Delaney A, Hirst M, Morin GB, Jones SJ, Tai IT, Marra MA.

Nat Methods. 2010 Oct;7(10):843-7. doi: 10.1038/nmeth.1503. Epub 2010 Sep 12.


Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells.

Crispo JA, Piché M, Ansell DR, Eibl JK, Tai IT, Kumar A, Ross GM, Tai TC.

Biochem Biophys Res Commun. 2010 Mar 19;393(4):773-8. doi: 10.1016/j.bbrc.2010.02.079. Epub 2010 Feb 18.


Secreted protein acidic and rich in cysteine-induced cellular senescence in colorectal cancers in response to irinotecan is mediated by P53.

Chan JM, Ho SH, Tai IT.

Carcinogenesis. 2010 May;31(5):812-9. doi: 10.1093/carcin/bgq034. Epub 2010 Feb 17.


The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells.

Khan MA, Steiner TS, Sham HP, Bergstrom KS, Huang JT, Assi K, Salh B, Tai IT, Li X, Vallance BA.

J Immunol. 2010 Mar 1;184(5):2305-13. doi: 10.4049/jimmunol.0900021. Epub 2010 Feb 3.


A rare case of isolated duodenal metastases from hepatocellular carcinoma associated with p53 and ki-67 expression: a case report.

Chung C, Al Ali J, Owen DA, Weiss AA, Yoshida EM, Tai IT.

Cases J. 2009 Dec 17;2:9344. doi: 10.1186/1757-1626-2-9344.

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