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The Microbiome in Atopic Dermatitis.

Paller AS, Kong HH, Seed P, Naik S, Scharschmidt TC, Gallo RL, Luger T, Irvine AD.

J Allergy Clin Immunol. 2018 Nov 23. pii: S0091-6749(18)31664-6. doi: 10.1016/j.jaci.2018.11.015. [Epub ahead of print]


The Atopic March and Atopic Multimorbidity: Many Trajectories, Many Pathways.

Paller AS, Spergel JM, Mina-Osorio P, Irvine AD.

J Allergy Clin Immunol. 2018 Nov 17. pii: S0091-6749(18)31638-5. doi: 10.1016/j.jaci.2018.11.006. [Epub ahead of print]


Human and computational models of atopic dermatitis: a review and perspectives by an expert panel of the International Eczema Council.

Eyerich K, Brown SJ, Perez White BE, Tanaka RJ, Bissonette R, Dhar S, Bieber T, Hijnen DJ, Guttman-Yassky E, Irvine A, Thyssen JP, Vestergaard C, Werfel T, Wollenberg A, Paller AS, Reynolds NJ.

J Allergy Clin Immunol. 2018 Nov 7. pii: S0091-6749(18)31573-2. doi: 10.1016/j.jaci.2018.10.033. [Epub ahead of print]


Next-generation anti-Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?

Clowry J, Irvine AD, McLoughlin RM.

J Allergy Clin Immunol. 2018 Sep 12. pii: S0091-6749(18)31290-9. doi: 10.1016/j.jaci.2018.08.038. [Epub ahead of print] No abstract available.


Antenatal Vitamin D Status Is Not Associated with Standard Neurodevelopmental Assessments at Age 5 Years in a Well-Characterized Prospective Maternal-Infant Cohort.

McCarthy EK, Murray DM, Malvisi L, Kenny LC, O'B Hourihane J, Irvine AD, Kiely ME.

J Nutr. 2018 Oct 1;148(10):1580-1586. doi: 10.1093/jn/nxy150.


Adhesion of Staphylococcus aureus to Corneocytes from Atopic Dermatitis Patients Is Controlled by Natural Moisturizing Factor Levels.

Feuillie C, Vitry P, McAleer MA, Kezic S, Irvine AD, Geoghegan JA, Dufrêne YF.

MBio. 2018 Aug 14;9(4). pii: e01184-18. doi: 10.1128/mBio.01184-18.


Antenatal vitamin D exposure and childhood eczema, food allergy, asthma and allergic rhinitis at 2 and 5 years of age in the atopic disease-specific Cork BASELINE Birth Cohort Study.

Hennessy Á, Hourihane JO, Malvisi L, Irvine AD, Kenny LC, Murray DM, Kiely ME.

Allergy. 2018 Nov;73(11):2182-2191. doi: 10.1111/all.13590. Epub 2018 Aug 29.


Clinical and genetic differences between pustular psoriasis subtypes.

Twelves S, Mostafa A, Dand N, Burri E, Farkas K, Wilson R, Cooper HL, Irvine AD, Oon HH, Kingo K, Köks S, Mrowietz U, Puig L, Reynolds N, Tan ES, Tanew A, Torz K, Trattner H, Valentine M, Wahie S, Warren RB, Wright A, Bata-Csörgő Z, Szell M, Griffiths CEM, Burden AD, Choon SE, Smith CH, Barker JN, Navarini AA, Capon F.

J Allergy Clin Immunol. 2018 Jul 21. pii: S0091-6749(18)31039-X. doi: 10.1016/j.jaci.2018.06.038. [Epub ahead of print]


Response to "Comment on: 'When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council'".

Simpson EL, Reynolds NJ, Flohr C, Paller AS, Silverberg JI, Cork MJ, Guttman-Yassky E, Irvine AD.

J Am Acad Dermatol. 2018 Aug;79(2):e25-e26. doi: 10.1016/j.jaad.2018.03.048. No abstract available.


Atopic dermatitis.

Weidinger S, Beck LA, Bieber T, Kabashima K, Irvine AD.

Nat Rev Dis Primers. 2018 Jun 21;4(1):1. doi: 10.1038/s41572-018-0001-z. Review.


Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes.

Pigors M, Common JEA, Wong XFCC, Malik S, Scott CA, Tabarra N, Liany H, Liu J, Limviphuvadh V, Maurer-Stroh S, Tang MBY, Lench N, Margolis DJ, van Heel DA, Mein CA, Novak N, Baurecht H, Weidinger S, McLean WHI, Irvine AD, O'Toole EA, Simpson MA, Kelsell DP.

J Invest Dermatol. 2018 Dec;138(12):2674-2677. doi: 10.1016/j.jid.2018.05.013. Epub 2018 May 30. No abstract available.


A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT).

Irvine AD, Jones AP, Beattie P, Baron S, Browne F, Ashoor F, O'Neill L, Rosala-Hallas A, Sach T, Spowart C, Taams L, Walker C, Wan M, Webb N, Williamson P, Flohr C; TREAT Trial Investigators.

Br J Dermatol. 2018 May 4. doi: 10.1111/bjd.16717. [Epub ahead of print]


Generalized lymphatic anomaly successfully treated with long-term, low-dose sirolimus.

Dvorakova V, Rea D, O'Regan GM, Irvine AD.

Pediatr Dermatol. 2018 Jul;35(4):533-534. doi: 10.1111/pde.13494. Epub 2018 Mar 26.


Correlation of Insulin-Like Growth Factor-I and -II Concentrations at Birth Measured by Mass Spectrometry and Growth from Birth to Two Months.

Hawkes CP, Murray DM, Kenny LC, Kiely M, O'B Hourihane J, Irvine AD, Wu Z, Argon Y, Reitz RE, McPhaul MJ, Grimberg A.

Horm Res Paediatr. 2018;89(2):122-131. doi: 10.1159/000486035. Epub 2018 Jan 18.


Catalogue of inherited disorders found among the Irish Traveller population.

Lynch SA, Crushell E, Lambert DM, Byrne N, Gorman K, King MD, Green A, O'Sullivan S, Browne F, Hughes J, Knerr I, Monavari AA, Cotter M, McConnell VPM, Kerr B, Jones SA, Keenan C, Murphy N, Cody D, Ennis S, Turner J, Irvine AD, Casey J.

J Med Genet. 2018 Apr;55(4):233-239. doi: 10.1136/jmedgenet-2017-104974. Epub 2018 Jan 22.


Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship.

Geoghegan JA, Irvine AD, Foster TJ.

Trends Microbiol. 2018 Jun;26(6):484-497. doi: 10.1016/j.tim.2017.11.008. Epub 2017 Dec 9. Review.


Variation in iodine food composition data has a major impact on estimates of iodine intake in young children.

Hennessy Á, Ní Chaoimh C, McCarthy EK, Kingston C, Irvine AD, Hourihane JO, Kenny LC, Murray DM, Kiely M.

Eur J Clin Nutr. 2018 Mar;72(3):410-419. doi: 10.1038/s41430-017-0030-9. Epub 2017 Nov 9.


The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab.

Paller AS, Czarnowicki T, Renert-Yuval Y, Holland K, Huynh T, Sadlier M, McAleer MA, Tran G, Geddes GC, Irvine AD, Guttman-Yassky E.

J Am Acad Dermatol. 2018 Mar;78(3):498-505.e2. doi: 10.1016/j.jaad.2017.10.026. Epub 2017 Oct 21.


Microcytosis is associated with low cognitive outcomes in healthy 2-year-olds in a high-resource setting.

McCarthy EK, Kiely ME, Hannon G, Ahearne C, Kenny LC, Hourihane JO, Irvine AD, Murray DM.

Br J Nutr. 2017 Sep;118(5):360-367. doi: 10.1017/S0007114517001945.


When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council.

Simpson EL, Bruin-Weller M, Flohr C, Ardern-Jones MR, Barbarot S, Deleuran M, Bieber T, Vestergaard C, Brown SJ, Cork MJ, Drucker AM, Eichenfield LF, Foelster-Holst R, Guttman-Yassky E, Nosbaum A, Reynolds NJ, Silverberg JI, Schmitt J, Seyger MMB, Spuls PI, Stalder JF, Su JC, Takaoka R, Traidl-Hoffmann C, Thyssen JP, van der Schaft J, Wollenberg A, Irvine AD, Paller AS.

J Am Acad Dermatol. 2017 Oct;77(4):623-633. doi: 10.1016/j.jaad.2017.06.042. Epub 2017 Aug 10.

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