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Year Number of Results
1992 1
1994 1
1996 2
1997 1
1998 3
1999 5
2000 10
2001 7
2002 7
2003 15
2004 19
2005 27
2006 36
2007 49
2008 57
2009 62
2010 76
2011 86
2012 117
2013 120
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2017 124
2018 153
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1,827 results

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Page 1
Insulin resistance and impaired adipogenesis.
Gustafson B, Hedjazifar S, Gogg S, Hammarstedt A, Smith U. Gustafson B, et al. Trends Endocrinol Metab. 2015 Apr;26(4):193-200. doi: 10.1016/j.tem.2015.01.006. Epub 2015 Feb 18. Trends Endocrinol Metab. 2015. PMID: 25703677 Review.
Hypertrophic obesity in humans, a characteristic of genetic predisposition for diabetes, is associated with abdominal obesity, ectopic fat accumulation, and the metabolic syndrome (MS), while the ability to recruit new adipocytes prevents this. We review the regulation of adip …
Hypertrophic obesity in humans, a characteristic of genetic predisposition for diabetes, is associated with abdominal obesity, ectopic fat a …
Insulin resistance and adipogenesis: role of transcription and secreted factors.
Penkov DN, Egorov AD, Mozgovaya MN, Tkachuk VA. Penkov DN, et al. Biochemistry (Mosc). 2013 Jan;78(1):8-18. doi: 10.1134/S0006297913010021. Biochemistry (Mosc). 2013. PMID: 23379555 Review.
Disorders in the insulin signaling cascade on development of insulin resistance can be caused by both changes in functioning of transcriptional factors and in the secretion profile of hormone-like substances. ...Thus, studies on the action mechanisms of facto …
Disorders in the insulin signaling cascade on development of insulin resistance can be caused by both changes in functi …
Role of Inflammatory Cytokines, Growth Factors and Adipokines in Adipogenesis and Insulin Resistance.
Al-Mansoori L, Al-Jaber H, Prince MS, Elrayess MA. Al-Mansoori L, et al. Inflammation. 2022 Feb;45(1):31-44. doi: 10.1007/s10753-021-01559-z. Epub 2021 Sep 18. Inflammation. 2022. PMID: 34536157 Free PMC article. Review.
These events can impact adipogenesis, causing dysfunction of the adipose tissue and increased risk of insulin resistance. ...Understanding the molecular mechanisms that mediate adipogenesis and insulin resistance could help the developmen …
These events can impact adipogenesis, causing dysfunction of the adipose tissue and increased risk of insulin resistance …
Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids.
Smith U, Kahn BB. Smith U, et al. J Intern Med. 2016 Nov;280(5):465-475. doi: 10.1111/joim.12540. Epub 2016 Oct 3. J Intern Med. 2016. PMID: 27699898 Free PMC article. Review.
Obesity, the major cause of the current global epidemic of type 2 diabetes (T2D), induces insulin resistance in peripheral insulin target tissues. Several mechanisms have been identified related to cross-talk between adipose tissue, skeletal muscle and liver. …
Obesity, the major cause of the current global epidemic of type 2 diabetes (T2D), induces insulin resistance in peripheral …
Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications.
Longo M, Zatterale F, Naderi J, Parrillo L, Formisano P, Raciti GA, Beguinot F, Miele C. Longo M, et al. Int J Mol Sci. 2019 May 13;20(9):2358. doi: 10.3390/ijms20092358. Int J Mol Sci. 2019. PMID: 31085992 Free PMC article. Review.
Excessive ectopic lipid accumulation leads to local inflammation and insulin resistance (IR). Indeed, overnutrition triggers uncontrolled inflammatory responses in WAT, leading to chronic low-grade inflammation, therefore fostering the progression of IR. ...
Excessive ectopic lipid accumulation leads to local inflammation and insulin resistance (IR). Indeed, overnutrition triggers u …
Contribution of adipogenesis to healthy adipose tissue expansion in obesity.
Vishvanath L, Gupta RK. Vishvanath L, et al. J Clin Invest. 2019 Oct 1;129(10):4022-4031. doi: 10.1172/JCI129191. J Clin Invest. 2019. PMID: 31573549 Free PMC article. Review.
Preferential accumulation of visceral WAT is associated with increased risk for insulin resistance, whereas subcutaneous WAT expansion is protective. Moreover, pathologic WAT remodeling, typically characterized by adipocyte hypertrophy, chronic inflammation, and fib …
Preferential accumulation of visceral WAT is associated with increased risk for insulin resistance, whereas subcutaneous WAT e …
Role of microRNAs on adipogenesis, chronic low-grade inflammation, and insulin resistance in obesity.
Cruz KJC, de Oliveira ARS, Morais JBS, Severo JS, Marreiro PhD DDN. Cruz KJC, et al. Nutrition. 2017 Mar;35:28-35. doi: 10.1016/j.nut.2016.10.003. Epub 2016 Oct 14. Nutrition. 2017. PMID: 28241987 Review.
The aim of this review was to convey updated information on the role of microRNAs in adipogenesis, chronic low-grade inflammation, and insulin resistance in obesity. Obesity is a chronic disease characterized by the presence of metabolic disorders (e.g., low- …
The aim of this review was to convey updated information on the role of microRNAs in adipogenesis, chronic low-grade inflammation, an …
[Obesity, adipogenesis and insulin resistance].
Ros Pérez M, Medina-Gómez G. Ros Pérez M, et al. Endocrinol Nutr. 2011 Aug-Sep;58(7):360-9. doi: 10.1016/j.endonu.2011.05.008. Epub 2011 Jul 22. Endocrinol Nutr. 2011. PMID: 21778123 Review. Spanish.
Insulin resistance precedes the development of type 2 diabetes mellitus and is also a common denominator in the so-called metabolic syndrome. ...Obesity is considered as a risk factor for developing insulin resistance. Increased adipose tissue has been …
Insulin resistance precedes the development of type 2 diabetes mellitus and is also a common denominator in the so-called meta …
Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity.
Hammarstedt A, Gogg S, Hedjazifar S, Nerstedt A, Smith U. Hammarstedt A, et al. Physiol Rev. 2018 Oct 1;98(4):1911-1941. doi: 10.1152/physrev.00034.2017. Physiol Rev. 2018. PMID: 30067159 Free article. Review.
When inadequate, this leads to a hypertrophic expansion of the cells with increased inflammation, insulin resistance, and a dysfunctional prolipolytic tissue. Epi-/genetic factors regulate SAT adipogenesis and genetic predisposition for type 2 diabetes is ass …
When inadequate, this leads to a hypertrophic expansion of the cells with increased inflammation, insulin resistance, and a dy …
Energy Metabolism Changes and Dysregulated Lipid Metabolism in Postmenopausal Women.
Ko SH, Jung Y. Ko SH, et al. Nutrients. 2021 Dec 20;13(12):4556. doi: 10.3390/nu13124556. Nutrients. 2021. PMID: 34960109 Free PMC article. Review.
Enhanced visceral fat lipolysis by adipose tissue lipoprotein lipase triggers the production of excessive free fatty acids, causing insulin resistance and metabolic diseases. Because genes involved in beta-oxidation are downregulated by estradiol loss, excess free f …
Enhanced visceral fat lipolysis by adipose tissue lipoprotein lipase triggers the production of excessive free fatty acids, causing insul …
1,827 results