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Items: 1 to 20 of 65

1.

Inonotus obliquus polysaccharides induces apoptosis of lung cancer cells and alters energy metabolism via the LKB1/AMPK axis.

Jiang S, Shi F, Lin H, Ying Y, Luo L, Huang D, Luo Z.

Int J Biol Macromol. 2019 Nov 18. pii: S0141-8130(19)32725-4. doi: 10.1016/j.ijbiomac.2019.10.174. [Epub ahead of print]

PMID:
31751687
2.

The pharmacological potential and possible molecular mechanisms of action of Inonotus obliquus from preclinical studies.

Duru KC, Kovaleva EG, Danilova IG, van der Bijl P.

Phytother Res. 2019 Aug;33(8):1966-1980. doi: 10.1002/ptr.6384. Epub 2019 Jun 17. Review.

PMID:
31209936
3.

Inotodiol inhibits cells migration and invasion and induces apoptosis via p53-dependent pathway in HeLa cells.

Zhang SD, Yu L, Wang P, Kou P, Li J, Wang LT, Wang W, Yao LP, Zhao XH, Fu YJ.

Phytomedicine. 2019 Jul;60:152957. doi: 10.1016/j.phymed.2019.152957. Epub 2019 May 13.

PMID:
31128995
4.

Synthesis of porous Pd nanoparticles by therapeutic chaga extract for highly efficient tri-modal cancer treatment.

Gil YG, Kang S, Chae A, Kim YK, Min DH, Jang H.

Nanoscale. 2018 Nov 1;10(42):19810-19817. doi: 10.1039/c8nr07172a.

PMID:
30334053
5.

Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells.

Baek J, Roh HS, Baek KH, Lee S, Lee S, Song SS, Kim KH.

J Ethnopharmacol. 2018 Oct 5;224:63-75. doi: 10.1016/j.jep.2018.05.025. Epub 2018 May 22.

PMID:
29800742
6.

Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia.

Shnyreva AV, Shnyreva AA, Espinoza C, Padrón JM, Trigos Á.

Int J Med Mushrooms. 2018;20(1):1-11. doi: 10.1615/IntJMedMushrooms.2018025250.

PMID:
29604909
7.

Chaga ( Inonotus obliquus), a Future Potential Medicinal Fungus in Oncology? A Chemical Study and a Comparison of the Cytotoxicity Against Human Lung Adenocarcinoma Cells (A549) and Human Bronchial Epithelial Cells (BEAS-2B).

Géry A, Dubreule C, André V, Rioult JP, Bouchart V, Heutte N, Eldin de Pécoulas P, Krivomaz T, Garon D.

Integr Cancer Ther. 2018 Sep;17(3):832-843. doi: 10.1177/1534735418757912. Epub 2018 Feb 27.

8.

Inotodiol suppresses proliferation of breast cancer in rat model of type 2 diabetes mellitus via downregulation of β-catenin signaling.

Zhang X, Bao C, Zhang J.

Biomed Pharmacother. 2018 Mar;99:142-150. doi: 10.1016/j.biopha.2017.12.084.

PMID:
29331760
9.

Growth-Inhibitory and Immunomodulatory Activities of Wild Mushrooms from North-Central British Columbia (Canada).

Smith A, Javed S, Barad A, Myhre V, Li WM, Reimer K, Massicotte HB, Tackaberry LE, Payne GW, Egger KN, Lee CH.

Int J Med Mushrooms. 2017;19(6):485-497. doi: 10.1615/IntJMedMushrooms.v19.i6.10.

PMID:
29199559
10.

Inonotus obliquus extract induces apoptosis in the human colorectal carcinoma's HCT-116 cell line.

Tsai CC, Li YS, Lin PP.

Biomed Pharmacother. 2017 Dec;96:1119-1126. doi: 10.1016/j.biopha.2017.11.111. Epub 2017 Nov 27.

PMID:
29174853
11.

Triterpenes with Anti-invasive Activity from Sclerotia of Inonotus obliquus.

Ryu K, Nakamura S, Nakashima S, Aihara M, Fukaya M, Iwami J, Asao Y, Yoshikawa M, Matsuda H.

Nat Prod Commun. 2017 Feb;12(2):225-228.

PMID:
30428217
12.

Identification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline viruses.

Tian J, Hu X, Liu D, Wu H, Qu L.

Int J Biol Macromol. 2017 Feb;95:160-167. doi: 10.1016/j.ijbiomac.2016.11.054. Epub 2016 Nov 16.

PMID:
27865960
13.

Polysaccharide isolated from the liquid culture broth of Inonotus obliquus suppresses invasion of B16-F10 melanoma cells via AKT/NF-κB signaling pathway.

Lee KR, Lee JS, Lee S, Son YK, Kim GR, Sim YC, Song JE, Ha SJ, Hong EK.

Mol Med Rep. 2016 Nov;14(5):4429-4435. doi: 10.3892/mmr.2016.5771. Epub 2016 Sep 23.

PMID:
27666322
14.

[Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)].

Nikitina SA, Khabibrakhmanova VR, Sysoeva MA.

Biomed Khim. 2016 May;62(4):369-75. doi: 10.18097/PBMC20166204369. Review. Russian.

PMID:
27562990
15.

Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice.

Arata S, Watanabe J, Maeda M, Yamamoto M, Matsuhashi H, Mochizuki M, Kagami N, Honda K, Inagaki M.

Heliyon. 2016 May 12;2(5):e00111. doi: 10.1016/j.heliyon.2016.e00111. eCollection 2016 May.

16.

Chemical constituents from Inonotus obliquus and their antitumor activities.

Zhao F, Xia G, Chen L, Zhao J, Xie Z, Qiu F, Han G.

J Nat Med. 2016 Oct;70(4):721-30. doi: 10.1007/s11418-016-1002-4. Epub 2016 May 14.

PMID:
27180084
17.

Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer.

Kang JH, Jang JE, Mishra SK, Lee HJ, Nho CW, Shin D, Jin M, Kim MK, Choi C, Oh SH.

J Ethnopharmacol. 2015 Sep 15;173:303-12. doi: 10.1016/j.jep.2015.07.030. Epub 2015 Jul 22.

PMID:
26210065
18.

Purification, characterization and biological activity of a novel polysaccharide from Inonotus obliquus.

Chen Y, Huang Y, Cui Z, Liu J.

Int J Biol Macromol. 2015 Aug;79:587-94. doi: 10.1016/j.ijbiomac.2015.05.016. Epub 2015 May 27.

PMID:
26026982
19.

Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells.

Lee HS, Kim EJ, Kim SH.

Nutr Res Pract. 2015 Apr;9(2):111-6. doi: 10.4162/nrp.2015.9.2.111. Epub 2015 Mar 12.

20.

Characterization of two water-soluble lignin metabolites with antiproliferative activities from Inonotus obliquus.

Wang Q, Mu H, Zhang L, Dong D, Zhang W, Duan J.

Int J Biol Macromol. 2015 Mar;74:507-14. doi: 10.1016/j.ijbiomac.2014.12.044. Epub 2015 Jan 10.

PMID:
25583019

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