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The role of IL-1 gene polymorphisms (IL1A, IL1B, and IL1RN) as a risk factor in unsuccessful implants retaining overdentures.
Sampaio Fernandes M, Vaz P, Braga AC, Sampaio Fernandes JC, Figueiral MH. Sampaio Fernandes M, et al. J Prosthodont Res. 2017 Oct;61(4):439-449. doi: 10.1016/j.jpor.2017.01.004. Epub 2017 Feb 17. J Prosthodont Res. 2017. PMID: 28223139
RESULTS: The performed prediction model included the following variables: mean probing depth, metal exposure, IL1B_allele2, maxillary edentulousness, and Fusobacterium nucleatum. The F. nucleatum showed significant association with the outcome. ...
RESULTS: The performed prediction model included the following variables: mean probing depth, metal exposure, IL1B_allele2, maxillary edentu …
Biofilm-induced profiles of immune response gene expression by oral epithelial cells.
Ebersole JL, Peyyala R, Gonzalez OA. Ebersole JL, et al. Mol Oral Microbiol. 2019 Feb;34(1):10.1111/omi.12251. doi: 10.1111/omi.12251. Mol Oral Microbiol. 2019. PMID: 30407731 Free PMC article.
We assessed gene expression patterns when epithelial cells were challenged with a multispecies biofilm composed of Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis representing a type of periodontopathic biofilm compared to challenge with the s …
We assessed gene expression patterns when epithelial cells were challenged with a multispecies biofilm composed of Streptococcus gordonii, …
Environmental lead effects on gene expression in oral epithelial cells.
Peyyala R, Emecen-Huja P, Ebersole JL. Peyyala R, et al. J Periodontal Res. 2018 Dec;53(6):961-971. doi: 10.1111/jre.12594. Epub 2018 Aug 26. J Periodontal Res. 2018. PMID: 30152021
Challenge of the cells with the biofilms (Streptococcus gordonii/Fusobacterium nucleatum/Porphyromonas gingivalis) resulted in significant increases in an array of host immune-related genes (134 of 511). ...
Challenge of the cells with the biofilms (Streptococcus gordonii/Fusobacterium nucleatum/Porphyromonas gingivalis) resulted in signif …
Oral Microbiome and Gingival Gene Expression of Inflammatory Biomolecules With Aging and Periodontitis.
Ebersole JL, Nagarajan R, Kirakodu S, Gonzalez OA. Ebersole JL, et al. Front Oral Health. 2021 Sep 17;2:725115. doi: 10.3389/froh.2021.725115. eCollection 2021. Front Oral Health. 2021. PMID: 35048048 Free PMC article.
Limited differences were noted in healthy tissues for chemokine expression with age; however, chemokine receptor genes were decreased in young but elevated in aged samples. IL1A, IL36A, and IL36G cytokines were decreased in the younger groups, with IL36A elevated in aged a …
Limited differences were noted in healthy tissues for chemokine expression with age; however, chemokine receptor genes were decreased in you …
Microbiological parameters associated with IL-1 gene polymorphisms in periodontitis patients.
Socransky SS, Haffajee AD, Smith C, Duff GW. Socransky SS, et al. J Clin Periodontol. 2000 Nov;27(11):810-8. doi: 10.1034/j.1600-051x.2000.027011810.x. J Clin Periodontol. 2000. PMID: 11073323
Prominent among species that were detected at higher levels in genotype positive subjects were members of the "red" and "orange" complexes and included: Bacteroides forsythus, Treponema denticola, the Fusobacterium nucleatum subspecies, Fusobacterium periodonticum, …
Prominent among species that were detected at higher levels in genotype positive subjects were members of the "red" and "orange" complexes a …