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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 1
2010 2
2011 3
2012 3
2013 2
2014 3
2015 5
2016 2
2017 7
2018 2
2019 3
2020 2
2021 1
2022 5
2023 2
2024 1

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40 results

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Page 1
Shared genetic risk factors and causal association between psoriasis and coronary artery disease.
Patrick MT, Li Q, Wasikowski R, Mehta N, Gudjonsson JE, Elder JT, Zhou X, Tsoi LC. Patrick MT, et al. Nat Commun. 2022 Nov 2;13(1):6565. doi: 10.1038/s41467-022-34323-4. Nat Commun. 2022. PMID: 36323703 Free PMC article.
Combining results from Bayesian credible interval analysis with independent information from genomic, epigenomic, and spatial chromatin organization, we prioritize genes (including IFIH1 and IL23A) that have implications for common molecular mechanisms involved in psori …
Combining results from Bayesian credible interval analysis with independent information from genomic, epigenomic, and spatial chromatin orga …
The Immunogenetics of Psoriasis.
Trovato E, Rubegni P, Cinotti E. Trovato E, et al. Adv Exp Med Biol. 2022;1367:105-117. doi: 10.1007/978-3-030-92616-8_4. Adv Exp Med Biol. 2022. PMID: 35286693
Psoriasis vulgaris is a chronic immune-mediated dermatological condition, resulting from an interaction between environmental triggers and genetic susceptibilities. ...The risk alleles of these genes can contribute to the overall state of susceptibility to psoriasis …
Psoriasis vulgaris is a chronic immune-mediated dermatological condition, resulting from an interaction between environmental trigger …
Multifactor dimensionality reduction reveals the effect of interaction between ERAP1 and IFIH1 polymorphisms in psoriasis susceptibility genes.
Zhang C, Qin Q, Li Y, Zheng X, Chen W, Zhen Q, Li B, Wang W, Sun L. Zhang C, et al. Front Genet. 2022 Nov 8;13:1009589. doi: 10.3389/fgene.2022.1009589. eCollection 2022. Front Genet. 2022. PMID: 36425068 Free PMC article.
Methods: We validated psoriasis susceptibility gene variants in an independent cohort of 5,414 patients with psoriasis and 5,556 controls. ...Conclusion: Our findings suggest that the interaction between ERAP1 and IFIH1 affects the development of psoriasis …
Methods: We validated psoriasis susceptibility gene variants in an independent cohort of 5,414 patients with psoriasis and 5,5 …
The immunogenetics of Psoriasis: A comprehensive review.
Harden JL, Krueger JG, Bowcock AM. Harden JL, et al. J Autoimmun. 2015 Nov;64:66-73. doi: 10.1016/j.jaut.2015.07.008. Epub 2015 Jul 26. J Autoimmun. 2015. PMID: 26215033 Free PMC article. Review.
Psoriasis vulgaris is a common, chronic inflammatory skin disease with a complex etiology involving genetic risk factors and environmental triggers. Here we describe the many known genetic predispositions of psoriasis with respect to immune genes and their encoded p …
Psoriasis vulgaris is a common, chronic inflammatory skin disease with a complex etiology involving genetic risk factors and environm …
Protective association exhibited by a single nucleotide polymorphism of the IFIH1 gene in patients with psoriasis: A case-control study.
Erazo Luna EV, Echavarría Sierra CJ, Cornejo-Sánchez DM, Sanclemente G, Pineda Trujillo NG. Erazo Luna EV, et al. Medwave. 2021 Dec 3;21(11):e8492. doi: 10.5867/medwave.2021.11.002099. Medwave. 2021. PMID: 34882124 English, Spanish.
This study aimed to evaluate the single nucleotide polymorphism rs10930046 (His460Arg) in the IFIH1 gene and its ssociation with the development of psoriasis in a Colombian population. ...CONCLUSIONS: The results obtained from this study confirm that carriers of the …
This study aimed to evaluate the single nucleotide polymorphism rs10930046 (His460Arg) in the IFIH1 gene and its ssociation with the …
The IFIH1/MDA5 rs1990760 Gene Variant (946Thr) Differentiates Early- vs. Late-Onset Skin Disease and Increases the Risk of Arthritis in a Spanish Cohort of Psoriasis.
Coto-Segura P, Vázquez-Coto D, Velázquez-Cuervo L, García-Lago C, Coto E, Queiro R. Coto-Segura P, et al. Int J Mol Sci. 2023 Sep 30;24(19):14803. doi: 10.3390/ijms241914803. Int J Mol Sci. 2023. PMID: 37834254 Free PMC article.
This protein is also upregulated in autoimmune diseases and psoriasis skin lesions. IFIH1 gene variants that increase MDA5 activity have been associated with an increased risk for immune-mediated diseases, including psoriasis. Our aim is to determine the asso …
This protein is also upregulated in autoimmune diseases and psoriasis skin lesions. IFIH1 gene variants that increase MDA5 act …
The genetics of psoriasis and psoriatic arthritis.
Chandran V. Chandran V. Clin Rev Allergy Immunol. 2013 Apr;44(2):149-56. doi: 10.1007/s12016-012-8303-5. Clin Rev Allergy Immunol. 2013. PMID: 22274791 Review.
These associations provide us with a model for the pathogenesis of psoriasis involving skin barrier function, innate and adaptive immunity. ...This article reviews the current status of genetic studies in psoriasis and PsA....
These associations provide us with a model for the pathogenesis of psoriasis involving skin barrier function, innate and adaptive imm …
Carriers of rare missense variants in IFIH1 are protected from psoriasis.
Li Y, Liao W, Cargill M, Chang M, Matsunami N, Feng BJ, Poon A, Callis-Duffin KP, Catanese JJ, Bowcock AM, Leppert MF, Kwok PY, Krueger GG, Begovich AB. Li Y, et al. J Invest Dermatol. 2010 Dec;130(12):2768-72. doi: 10.1038/jid.2010.214. Epub 2010 Jul 29. J Invest Dermatol. 2010. PMID: 20668468 Free PMC article.
Testing of 25,000 putative functional single-nucleotide polymorphisms (SNPs) across the human genome in a genetic association study has identified three psoriasis genes, IL12B, IL23R, and IL13. We now report evidence for the association of psoriasis risk with missen …
Testing of 25,000 putative functional single-nucleotide polymorphisms (SNPs) across the human genome in a genetic association study has iden …
RIG-I-Like Receptor Signaling in Singleton-Merten Syndrome.
Lu C, MacDougall M. Lu C, et al. Front Genet. 2017 Sep 12;8:118. doi: 10.3389/fgene.2017.00118. eCollection 2017. Front Genet. 2017. PMID: 28955379 Free PMC article. Review.
Singleton-Merten syndrome (SMS) is an autosomal dominant, multi-system innate immune disorder characterized by early and severe aortic and valvular calcification, dental and skeletal abnormalities, psoriasis, glaucoma, and other varying clinical findings. Recently we ident …
Singleton-Merten syndrome (SMS) is an autosomal dominant, multi-system innate immune disorder characterized by early and severe aortic and v …
Psoriasis risk SNPs and their association with HIV-1 control.
Nititham J, Gupta R, Zeng X, Hartogensis W, Nixon DF, Deeks SG, Hecht FM, Liao W. Nititham J, et al. Hum Immunol. 2017 Feb;78(2):179-184. doi: 10.1016/j.humimm.2016.10.018. Epub 2016 Oct 31. Hum Immunol. 2017. PMID: 27810495 Free PMC article.
However, such polymorphisms may have the potential to heighten the risk of autoimmune disease. Here, we investigated whether psoriasis-associated single nucleotide polymorphisms influence host control of HIV-1 infection. ...A number of genetic variants outside the MHC (SOX …
However, such polymorphisms may have the potential to heighten the risk of autoimmune disease. Here, we investigated whether psoriasis …
40 results