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Best matches for hypomethylation cancer:

DNA Hypomethylating Drugs in Cancer Therapy. Sato T et al. Cold Spring Harb Perspect Med. (2017)

Oncogenic roles of DNA hypomethylation through the activation of cancer-germline genes. Van Tongelen A et al. Cancer Lett. (2017)

Increased Global DNA Hypomethylation in Distant Metastatic and Dedifferentiated Thyroid Cancer. Klein Hesselink EN et al. J Clin Endocrinol Metab. (2018)

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Items: 1 to 20 of 2884


DNA hypomethylation-related overexpression of SFN, GORASP2 and ZYG11A is a novel prognostic biomarker for early stage lung adenocarcinoma.

Husni RE, Shiba-Ishii A, Nakagawa T, Dai T, Kim Y, Hong J, Sakashita S, Sakamoto N, Sato Y, Noguchi M.

Oncotarget. 2019 Feb 26;10(17):1625-1636. doi: 10.18632/oncotarget.26676. eCollection 2019 Feb 26.


Hypomethylation-mediated activation of cancer/testis antigen KK-LC-1 facilitates hepatocellular carcinoma progression through activating the Notch1/Hes1 signalling.

Chen Z, Zuo X, Pu L, Zhang Y, Han G, Zhang L, Wu Z, You W, Qin J, Dai X, Shen H, Wang X, Wu J.

Cell Prolif. 2019 Mar 20:e12581. doi: 10.1111/cpr.12581. [Epub ahead of print]


Highly variant DNA methylation in normal tissues identifies a distinct subclass of cancer patients.

Ghosh J, Schultz B, Coutifaris C, Sapienza C.

Adv Cancer Res. 2019;142:1-22. doi: 10.1016/bs.acr.2019.01.006. Epub 2019 Feb 27.


PFKFB2 Promoter Hypomethylation as Recurrence Predictive Marker in Well-Differentiated Thyroid Carcinomas.

Camargo Barros-Filho M, Barreto Menezes de Lima L, Bisarro Dos Reis M, Bette Homem de Mello J, Moraes Beltrami C, Lopes Pinto CA, Kowalski LP, Rogatto SR.

Int J Mol Sci. 2019 Mar 16;20(6). pii: E1334. doi: 10.3390/ijms20061334.


Integrative analysis identifies DNMTs against immune-infiltrating neutrophils and dendritic cells in colorectal cancer.

Shi Q, Shen L, Gan J, He L, Lin J, Guo S, Xiong Z, Lin J, Zhang S.

Epigenetics. 2019 Mar 16:1-13. doi: 10.1080/15592294.2019.1588684. [Epub ahead of print]


Investigating the expression and promoter methylation of RET gene in patients with medullary thyroid cancer with unmutated RET.

Shakiba E, Movahedi M, Majd A, Hedayati M.

J Cell Physiol. 2019 Mar 14. doi: 10.1002/jcp.28295. [Epub ahead of print]


Tracking Decitabine Incorporation into Malignant Myeloid Cell DNA in vitro and in vivo by LC-MS/MS with Enzymatic Digestion.

Chilakala S, Feng Y, Li L, Mahfouz R, Quteba E, Saunthararajah Y, Xu Y.

Sci Rep. 2019 Mar 14;9(1):4558. doi: 10.1038/s41598-019-41070-y.


Evaluation of DNA Methylation Changes and Micronuclei in Workers Exposed to a Construction Environment.

Silva IR, Ramos MCAS, Arantes LMRB, Lengert AVH, Oliveira MA, Cury FP, Martins Pereira G, Santos AG, Barbosa F Jr, Vasconcellos PC, Cuenin C, Herceg Z, Silveira HCS.

Int J Environ Res Public Health. 2019 Mar 13;16(6). pii: E902. doi: 10.3390/ijerph16060902.


Epigenomic profiling of newborns with isolated orofacial clefts reveals widespread DNA methylation changes and implicates metastable epiallele regions in disease risk.

Gonseth S, Shaw GM, Roy R, Segal MR, Asrani K, Rine J, Wiemels J, Marini NJ.

Epigenetics. 2019 Mar 14:1-16. doi: 10.1080/15592294.2019.1581591. [Epub ahead of print]


Genetic and epigenetic characteristics in ovarian tissues from polycystic ovary syndrome patients with irregular menstruation resemble those of ovarian cancer.

Jiao J, Sagnelli M, Shi B, Fang Y, Shen Z, Tang T, Dong B, Li D, Wang X.

BMC Endocr Disord. 2019 Mar 12;19(1):30. doi: 10.1186/s12902-019-0356-5.


Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic Memory.

Turner DC, Seaborne RA, Sharples AP.

Sci Rep. 2019 Mar 12;9(1):4251. doi: 10.1038/s41598-019-40787-0.


Soy Isoflavone Supplementation Increases Long Interspersed Nucleotide Element-1 (LINE-1) Methylation in Head and Neck Squamous Cell Carcinoma.

Rozek LS, Virani S, Bellile EL, Taylor JMG, Sartor MA, Zarins KR, Virani A, Cote C, Worden FP, Mark MEP, McLean SA, Duffy SA, Yoo GH, Saba NF, Shin DM, Kucuk O, Wolf GT.

Nutr Cancer. 2019 Mar 12:1-9. doi: 10.1080/01635581.2019.1577981. [Epub ahead of print]


A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade.

Ruan H, Hu Q, Wen D, Chen Q, Chen G, Lu Y, Wang J, Cheng H, Lu W, Gu Z.

Adv Mater. 2019 Mar 11:e1806957. doi: 10.1002/adma.201806957. [Epub ahead of print]


A network-based approach to identify DNA methylation and its involved molecular pathways in testicular germ cell tumors.

Bo H, Cao K, Tang R, Zhang H, Gong Z, Liu Z, Liu J, Li J, Fan L.

J Cancer. 2019 Jan 29;10(4):893-902. doi: 10.7150/jca.27491. eCollection 2019.


Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy.

Emran AA, Chatterjee A, Rodger EJ, Tiffen JC, Gallagher SJ, Eccles MR, Hersey P.

Trends Immunol. 2019 Mar 7. pii: S1471-4906(19)30027-4. doi: 10.1016/ [Epub ahead of print] Review.


Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3.

Puccini A, Loupakis F, Stintzing S, Cao S, Battaglin F, Togunaka R, Naseem M, Berger MD, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Weisenberger DJ, Liang G, Cremolini C, Heinemann V, Falcone A, Millstein J, Lenz HJ.

Eur J Cancer. 2019 Mar 7;111:138-147. doi: 10.1016/j.ejca.2019.01.105. [Epub ahead of print]


Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer.

Gu S, Lin S, Ye D, Qian S, Jiang D, Zhang X, Li Q, Yang J, Ying X, Li Z, Tang M, Wang J, Jin M, Chen K.

Clin Epigenetics. 2019 Mar 7;11(1):41. doi: 10.1186/s13148-019-0628-y.


Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia.

Richter A, Roolf C, Hamed M, Gladbach YS, Sender S, Konkolefski C, Knübel G, Sekora A, Fuellen G, Vollmar B, Murua Escobar H, Junghanss C.

BMC Cancer. 2019 Mar 6;19(1):202. doi: 10.1186/s12885-019-5411-0.


Examination of methylation changes of VIM, CXCR4, DOK7, and SPDEF genes in peripheral blood DNA in breast cancer patients.

Shirkavand A, Boroujeni ZN, Aleyasin SA.

Indian J Cancer. 2018 Oct-Dec;55(4):366-371. doi: 10.4103/ijc.IJC_100_18.


Genetics/epigenetics/allergy: The gun is loaded … but what pulls the trigger?

Bellanti JA.

Allergy Asthma Proc. 2019 Mar 1;40(2):76-83. doi: 10.2500/aap.2019.40.4205.


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