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Items: 1 to 20 of 99


Antipsychotic-induced metabolic alterations: recounting the mechanistic insights, therapeutic targets and pharmacological alternatives.

Singh R, Bansal Y, Medhi B, Kuhad A.

Eur J Pharmacol. 2018 Dec 7. pii: S0014-2999(18)30705-2. doi: 10.1016/j.ejphar.2018.12.003. [Epub ahead of print] Review.


Potential drug-drug interactions in outpatient department of a tertiary care hospital in Pakistan: a cross-sectional study.

Ismail M, Noor S, Harram U, Haq I, Haider I, Khadim F, Khan Q, Ali Z, Muhammad T, Asif M.

BMC Health Serv Res. 2018 Oct 10;18(1):762. doi: 10.1186/s12913-018-3579-7.


A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.

Davis SL, Eckhardt SG, Diamond JR, Messersmith WA, Dasari A, Weekes CD, Lieu CH, Kane M, Choon Tan A, Pitts TM, Leong S.

Oncologist. 2018 Aug 23. pii: theoncologist.2018-0315. doi: 10.1634/theoncologist.2018-0315. [Epub ahead of print]


Inhibition of aldose-reductase-2 by a benzofuroxane derivative bf-5m increases the expression of kcne1, kcnq1 in high glucose cultured H9c2 cardiac cells and sudden cardiac death.

Trotta MC, Salerno M, Brigida AL, Monda V, Messina A, Fiore C, Avola R, Bernardini R, Sessa F, Marsala G, Zanghì GN, Messina G, D'Amico M, Di Filippo C.

Oncotarget. 2017 Dec 14;9(25):17257-17269. doi: 10.18632/oncotarget.23270. eCollection 2018 Apr 3.


O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts.

Yu P, Hu L, Xie J, Chen S, Huang L, Xu Z, Liu X, Zhou Q, Yuan P, Yan X, Jin J, Shen Y, Zhu W, Fu L, Chen Q, Yu J, Hu J, Cao Q, Wan R, Hong K.

Int J Cardiol. 2018 Jun 1;260:74-81. doi: 10.1016/j.ijcard.2018.02.099. Epub 2018 Feb 27.


Usefulness of simultaneous and sequential monitoring of glucose level and electrocardiogram in monkeys treated with gatifloxacin under conscious and nonrestricted conditions.

Yoshimatsu Y, Ishizaka T, Chiba K, Mori K.

Exp Anim. 2018 May 10;67(2):281-290. doi: 10.1538/expanim.17-0136. Epub 2018 Jan 3.


Multiple Endocrine Neoplasia Type 1.

Giusti F, Marini F, Brandi ML.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2005 Aug 31 [updated 2017 Dec 14].


Sevoflurane causes greater QTc interval prolongation in chronically hyperglycemic patients than in normoglycemic patients.

Kimura S, Nakao S, Kitaura A, Iwamoto T, Houri K, Matsushima M, Hamasaki S.

PLoS One. 2017 Dec 1;12(12):e0188555. doi: 10.1371/journal.pone.0188555. eCollection 2017.


The association of long-term glycaemic variability versus sustained chronic hyperglycaemia with heart rate-corrected QT interval in patients with type 2 diabetes.

Su JB, Yang XH, Zhang XL, Cai HL, Huang HY, Zhao LH, Xu F, Chen T, Cheng XB, Wang XQ, Lu Y.

PLoS One. 2017 Aug 28;12(8):e0183055. doi: 10.1371/journal.pone.0183055. eCollection 2017.


Arrhythmogenic gene remodelling in elderly patients with type 2 diabetes with aortic stenosis and normal left ventricular ejection fraction.

Ashrafi R, Modi P, Oo AY, Pullan DM, Jian K, Zhang H, Gerges JY, Hart G, Boyett MR, Davis GK, Wilding JPH.

Exp Physiol. 2017 Nov 1;102(11):1424-1434. doi: 10.1113/EP086412. Epub 2017 Sep 24.


Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial Fibrillation.

Aromolaran AS, Boutjdir M.

Front Physiol. 2017 Jun 21;8:431. doi: 10.3389/fphys.2017.00431. eCollection 2017. Review.


Psychotic and Bipolar Disorders: Antipsychotic Drugs.

Holder SD, Edmunds AL, Morgan S.

FP Essent. 2017 Apr;455:23-29. Review.


Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects.

Hyltén-Cavallius L, Iepsen EW, Christiansen M, Graff C, Linneberg A, Pedersen O, Holst JJ, Hansen T, Torekov SS, Kanters JK.

Heart Rhythm. 2017 Aug;14(8):1165-1170. doi: 10.1016/j.hrthm.2017.04.018. Epub 2017 Apr 9.


Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia.

Hyltén-Cavallius L, Iepsen EW, Wewer Albrechtsen NJ, Svendstrup M, Lubberding AF, Hartmann B, Jespersen T, Linneberg A, Christiansen M, Vestergaard H, Pedersen O, Holst JJ, Kanters JK, Hansen T, Torekov SS.

Circulation. 2017 May 2;135(18):1705-1719. doi: 10.1161/CIRCULATIONAHA.116.024279. Epub 2017 Feb 24.


Cardiac Effects of Sulfonylurea-Related Hypoglycemia.

Middleton TL, Wong J, Molyneaux L, Brooks BA, Yue DK, Twigg SM, Wu T.

Diabetes Care. 2017 May;40(5):663-670. doi: 10.2337/dc16-1972. Epub 2017 Feb 21.


Assessing the burden of treatment-emergent adverse events associated with atypical antipsychotic medications.

Llorca PM, Lançon C, Hartry A, Brown TM, DiBenedetti DB, Kamat SA, François C.

BMC Psychiatry. 2017 Feb 13;17(1):67. doi: 10.1186/s12888-017-1213-6.


Rapidly progressive cataract formation associated with non-small-cell lung cancer therapy.

Liu E, Kopani K.

J Cataract Refract Surg. 2016 Dec;42(12):1838-1840. doi: 10.1016/j.jcrs.2016.11.006.


AC0010, an Irreversible EGFR Inhibitor Selectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients.

Xu X, Mao L, Xu W, Tang W, Zhang X, Xi B, Xu R, Fang X, Liu J, Fang C, Zhao L, Wang X, Jiang J, Hu P, Zhao H, Zhang L.

Mol Cancer Ther. 2016 Nov;15(11):2586-2597. Epub 2016 Aug 29.


Hyperglycemia and subsequent torsades de pointes with marked QT prolongation during refeeding.

Nakashima T, Kubota T, Takasugi N, Kitagawa Y, Yoshida T, Ushikoshi H, Kawasaki M, Nishigaki K, Ogura S, Minatoguchi S.

Nutrition. 2017 Jan;33:145-148. doi: 10.1016/j.nut.2016.05.012. Epub 2016 Jun 5.


Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.

Cao L, Chen X, Xiao X, Ma Q, Li W.

Int J Oncol. 2016 Aug;49(2):735-43. doi: 10.3892/ijo.2016.3559. Epub 2016 Jun 3.


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