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Best matches for heat shock protein AND ("QT" OR Torsad*):

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Items: 1 to 20 of 28

1.

Electrophysiological evaluation of pentamidine and 17-AAG in human stem cell-derived cardiomyocytes for safety assessment.

Asahi Y, Nomura F, Abe Y, Doi M, Sakakura T, Takasuna K, Yasuda K.

Eur J Pharmacol. 2018 Nov 1;842:221-230. doi: 10.1016/j.ejphar.2018.10.046. [Epub ahead of print]

PMID:
30391349
2.

The Role of Serotonin in Ventricular Repolarization in Pregnant Mice.

Cui S, Park H, Park H, Mun D, Lee SH, Kim H, Yun N, Kim H, Kim M, Pak HN, Lee MH, Joung B.

Yonsei Med J. 2018 Mar;59(2):279-286. doi: 10.3349/ymj.2018.59.2.279.

3.

Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels.

Hantouche C, Williamson B, Valinsky WC, Solomon J, Shrier A, Young JC.

J Biol Chem. 2017 Feb 10;292(6):2287-2300. doi: 10.1074/jbc.M116.752618. Epub 2016 Dec 20.

4.

Tetrameric Assembly of K+ Channels Requires ER-Located Chaperone Proteins.

Li K, Jiang Q, Bai X, Yang YF, Ruan MY, Cai SQ.

Mol Cell. 2017 Jan 5;65(1):52-65. doi: 10.1016/j.molcel.2016.10.027. Epub 2016 Dec 1.

5.

M3 Muscarinic Receptor Signaling Stabilizes a Novel Mutant Human Ether-a-Go-Go-Related Gene Channel Protein via Phosphorylation of Heat Shock Factor 1 in Transfected Cells.

Mahati E, Li P, Kurata Y, Maharani N, Ikeda N, Sakata S, Ogura K, Miake J, Aiba T, Shimizu W, Nakasone N, Ninomiya H, Higaki K, Yamamoto K, Nakai A, Shirayoshi Y, Hisatome I.

Circ J. 2016 Nov 25;80(12):2443-2452. Epub 2016 Nov 1.

6.

Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1.

Kondo T, Hisatome I, Yoshimura S, Mahati E, Notsu T, Li P, Iitsuka K, Kato M, Ogura K, Miake J, Aiba T, Shimizu W, Kurata Y, Sakata S, Nakasone N, Ninomiya H, Nakai A, Higaki K, Kawata Y, Shirayoshi Y, Yoshida A, Yamamoto K.

J Arrhythm. 2016 Oct;32(5):433-440. Epub 2015 Nov 25.

7.

hERG quality control and the long QT syndrome.

Foo B, Williamson B, Young JC, Lukacs G, Shrier A.

J Physiol. 2016 May 1;594(9):2469-81. doi: 10.1113/JP270531. Epub 2016 Feb 9. Review.

8.

Heat shock protein 70 gene polymorphisms' influence on the electrophysiology of long QT syndrome.

Ali A, Qureshi SF, Medikare V, Venkateshwari A, Calambur N, Rao H, Jayakrishnan MP, Shenthar J, Thangaraj K, Nallari P.

J Interv Card Electrophysiol. 2016 Mar;45(2):119-30. doi: 10.1007/s10840-015-0082-5. Epub 2015 Dec 16.

PMID:
26670457
9.

High Glucose Represses hERG K+ Channel Expression through Trafficking Inhibition.

Shi YQ, Yan M, Liu LR, Zhang X, Wang X, Geng HZ, Zhao X, Li BX.

Cell Physiol Biochem. 2015;37(1):284-96. doi: 10.1159/000430353. Epub 2015 Aug 24.

10.

Estradiol regulates human QT-interval: acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking.

Anneken L, Baumann S, Vigneault P, Biliczki P, Friedrich C, Xiao L, Girmatsion Z, Takac I, Brandes RP, Kissler S, Wiegratz I, Zumhagen S, Stallmeyer B, Hohnloser SH, Klingenheben T, Schulze-Bahr E, Nattel S, Ehrlich JR.

Eur Heart J. 2016 Feb 14;37(7):640-50. doi: 10.1093/eurheartj/ehv371. Epub 2015 Aug 12.

11.

RING finger protein RNF207, a novel regulator of cardiac excitation.

Roder K, Werdich AA, Li W, Liu M, Kim TY, Organ-Darling LE, Moshal KS, Hwang JM, Lu Y, Choi BR, MacRae CA, Koren G.

J Biol Chem. 2014 Dec 5;289(49):33730-40. doi: 10.1074/jbc.M114.592295. Epub 2014 Oct 3.

12.

The rescuable function and mechanism of resveratrol on As₂O₃-induced hERG K⁺ channel deficiency.

Zhao X, Zhang KP, Huang T, Yan CC, Liu LR, Zhu QL, Guo FF, Liu C, Li BX.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Nov;387(11):1079-89. doi: 10.1007/s00210-014-1019-8. Epub 2014 Aug 10.

PMID:
25107562
13.
14.

Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.

Iwai C, Li P, Kurata Y, Hoshikawa Y, Morikawa K, Maharani N, Higaki K, Sasano T, Notsu T, Ishido Y, Miake J, Yamamoto Y, Shirayoshi Y, Ninomiya H, Nakai A, Murata S, Yoshida A, Yamamoto K, Hiraoka M, Hisatome I.

Cardiovasc Res. 2013 Dec 1;100(3):520-8. doi: 10.1093/cvr/cvt200. Epub 2013 Aug 20.

PMID:
23963841
15.

Pharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia.

Walker AR, Klisovic R, Johnston JS, Jiang Y, Geyer S, Kefauver C, Binkley P, Byrd JC, Grever MR, Garzon R, Phelps MA, Marcucci G, Blum KA, Blum W.

Leuk Lymphoma. 2013 Sep;54(9):1996-2002. doi: 10.3109/10428194.2012.760733. Epub 2013 Jan 24.

16.

Alpha B-crystallin prevents the arrhythmogenic effects of particulate matter isolated from ambient air by attenuating oxidative stress.

Park H, Park S, Jeon H, Song BW, Kim JB, Kim CS, Pak HN, Hwang KC, Lee MH, Chung JH, Joung B.

Toxicol Appl Pharmacol. 2013 Jan 15;266(2):267-75. doi: 10.1016/j.taap.2012.10.013. Epub 2012 Nov 12.

PMID:
23153557
17.

Novel effects of extracts from poisonous mushrooms on expression and function of the human ether-a-go-go-related gene channel.

Li P, Tanaka S, Ichiyanagi T, Ninomiya H, Ting Y, Utami SB, Aimi T, Shirayoshi Y, Miake J, Hisatome I.

Biol Pharm Bull. 2011;34(9):1474-80.

18.

Reciprocal control of hERG stability by Hsp70 and Hsc70 with implication for restoration of LQT2 mutant stability.

Li P, Ninomiya H, Kurata Y, Kato M, Miake J, Yamamoto Y, Igawa O, Nakai A, Higaki K, Toyoda F, Wu J, Horie M, Matsuura H, Yoshida A, Shirayoshi Y, Hiraoka M, Hisatome I.

Circ Res. 2011 Feb 18;108(4):458-68. doi: 10.1161/CIRCRESAHA.110.227835. Epub 2010 Dec 23.

PMID:
21183741
19.

Simultaneous gene expression signature of heart and peripheral blood mononuclear cells in astemizole-treated rats.

Lee EH, Oh JH, Park HJ, Kim DG, Lee JH, Kim CY, Kwon MS, Yoon S.

Arch Toxicol. 2010 Aug;84(8):609-18. doi: 10.1007/s00204-010-0529-5. Epub 2010 Mar 11.

PMID:
20221588
20.

Hsp40 chaperones promote degradation of the HERG potassium channel.

Walker VE, Wong MJ, Atanasiu R, Hantouche C, Young JC, Shrier A.

J Biol Chem. 2010 Jan 29;285(5):3319-29. doi: 10.1074/jbc.M109.024000. Epub 2009 Nov 25.

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