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Items: 1 to 20 of 21

1.

Aluminum-substituted heme domain of P450BM-3 (BMP): introducing a heme-derived fluorescent probe for studies of substrate binding and protein-protein interactions in cytochromes P450.

Davydov DR, Ponomarev GV, Bobrovnikova-Marjon E, Haines DC, Peterson JA.

Biotechnol Appl Biochem. 2013 Jan-Feb;60(1):41-51. doi: 10.1002/bab.1085.

PMID:
23586991
2.

Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling.

De Matteis F, Ballou DP, Coon MJ, Estabrook RW, Haines DC.

Biochem Pharmacol. 2012 Aug 1;84(3):374-82. doi: 10.1016/j.bcp.2012.04.016. Epub 2012 Apr 28.

PMID:
22564776
3.

A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation.

Haines DC, Hegde A, Chen B, Zhao W, Bondlela M, Humphreys JM, Mullin DA, Tomchick DR, Machius M, Peterson JA.

Biochemistry. 2011 Oct 4;50(39):8333-41. doi: 10.1021/bi201099j. Epub 2011 Sep 6.

4.

Comparison of brain mitochondrial cytochrome c oxidase activity with cyanide LD(50) yields insight into the efficacy of prophylactics.

Marziaz ML, Frazier K, Guidry PB, Ruiz RA, Petrikovics I, Haines DC.

J Appl Toxicol. 2013 Jan;33(1):50-5. doi: 10.1002/jat.1709. Epub 2011 Jul 13.

PMID:
21751223
5.

Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin.

Horke S, Witte I, Altenhöfer S, Wilgenbus P, Goldeck M, Förstermann U, Xiao J, Kramer GL, Haines DC, Chowdhary PK, Haley RW, Teiber JF.

Biochem J. 2010 Jan 27;426(1):73-83. doi: 10.1042/BJ20091414.

PMID:
19925453
6.

A single mutation in P450BM-3 enhances acyl homoserine lactone: acyl homoserine substrate binding selectivity nearly 250-fold.

Chowdhary PK, Stewart L, Lopez C, Haines DC.

J Biotechnol. 2008 Jul 31;135(4):374-6. doi: 10.1016/j.jbiotec.2008.05.005. Epub 2008 May 20.

PMID:
18586345
7.

Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone.

Teiber JF, Horke S, Haines DC, Chowdhary PK, Xiao J, Kramer GL, Haley RW, Draganov DI.

Infect Immun. 2008 Jun;76(6):2512-9. doi: 10.1128/IAI.01606-07. Epub 2008 Mar 17.

8.

Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.

Haines DC, Chen B, Tomchick DR, Bondlela M, Hegde A, Machius M, Peterson JA.

Biochemistry. 2008 Mar 25;47(12):3662-70. doi: 10.1021/bi7023964. Epub 2008 Feb 26.

PMID:
18298086
9.

Bacillus megaterium CYP102A1 oxidation of acyl homoserine lactones and acyl homoserines.

Chowdhary PK, Keshavan N, Nguyen HQ, Peterson JA, González JE, Haines DC.

Biochemistry. 2007 Dec 18;46(50):14429-37. Epub 2007 Nov 20.

PMID:
18020460
10.

Interactions of substrates at the surface of P450s can greatly enhance substrate potency.

Hegde A, Haines DC, Bondlela M, Chen B, Schaffer N, Tomchick DR, Machius M, Nguyen H, Chowdhary PK, Stewart L, Lopez C, Peterson JA.

Biochemistry. 2007 Dec 11;46(49):14010-7. Epub 2007 Nov 16.

PMID:
18004886
11.

Cloning, expression and characterization of a fast self-sufficient P450: CYP102A5 from Bacillus cereus.

Chowdhary PK, Alemseghed M, Haines DC.

Arch Biochem Biophys. 2007 Dec 1;468(1):32-43. Epub 2007 Sep 19.

PMID:
17945181
12.

Obligatory intermolecular electron-transfer from FAD to FMN in dimeric P450BM-3.

Kitazume T, Haines DC, Estabrook RW, Chen B, Peterson JA.

Biochemistry. 2007 Oct 23;46(42):11892-901. Epub 2007 Sep 29.

PMID:
17902705
13.
14.

L-Canavanine made by Medicago sativa interferes with quorum sensing in Sinorhizobium meliloti.

Keshavan ND, Chowdhary PK, Haines DC, González JE.

J Bacteriol. 2005 Dec;187(24):8427-36.

15.

Modulation of zinc- and cobalt-binding affinities through changes in the stability of the zinc ribbon protein L36.

Kou W, Kolla HS, Ortiz-Acevedo A, Haines DC, Junker M, Dieckmann GR.

J Biol Inorg Chem. 2005 Mar;10(2):167-80. Epub 2005 Mar 4.

PMID:
15747135
16.
17.

Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction.

Wimalasena DS, Jayatillake SP, Haines DC, Wimalasena K.

Biochem J. 2002 Oct 1;367(Pt 1):77-85.

18.

Pivotal role of water in the mechanism of P450BM-3.

Haines DC, Tomchick DR, Machius M, Peterson JA.

Biochemistry. 2001 Nov 13;40(45):13456-65.

PMID:
11695892
19.

The FMN-binding domain of cytochrome P450BM-3: resolution, reconstitution, and flavin analogue substitution.

Haines DC, Sevrioukova IF, Peterson JA.

Biochemistry. 2000 Aug 8;39(31):9419-29.

PMID:
10924137
20.

Chiral multisubstrate inhibitors of dopamine beta-monooxygenase: evidence for dual modes of interaction.

Wimalasena K, Wimalasena DS, Dharmasena S, Haines DC, Alliston KR.

Biochemistry. 1997 Jun 10;36(23):7144-53.

PMID:
9188714

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