Anaesthetic management of children with Joubert syndrome

Paediatr Anaesth. 1997;7(3):251-3. doi: 10.1046/j.1460-9592.1997.d01-65.x.

Abstract

We report the anaesthetic management of two children with Joubert syndrome. Children with this syndrome have abnormalities of respiratory control due to changes in the brainstem and cerebellum. They are extremely sensitive to the respiratory depressant effects of anaesthetic agents, including nitrous oxide. Anaesthesia using inhalational induction, controlled ventilation, avoidance of opioids, and close postoperative monitoring is recommended.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, General / adverse effects*
  • Anesthesia, General / methods*
  • Apnea / etiology*
  • Cerebellar Diseases / complications*
  • Cerebellum / abnormalities*
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Intraoperative Care
  • Intraoperative Complications / etiology
  • Intraoperative Complications / therapy
  • Monitoring, Physiologic
  • Postoperative Care
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy
  • Syndrome