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Exercise-induced changes in gene expression do not mediate post exertional malaise in Gulf War illness.
Boruch AE, Lindheimer JB, Ninneman JV, Wylie GR, Alexander T, Klein-Adams JC, Stegner AJ, Gretzon NP, Samy B, Falvo MJ, Cook DB. Boruch AE, et al. Brain Behav Immun Health. 2023 Mar 11;29:100612. doi: 10.1016/j.bbih.2023.100612. eCollection 2023 May. Brain Behav Immun Health. 2023. PMID: 36950022 Free PMC article.
OBJECTIVES: To investigate whether PEM is meditated by gene expression in Veterans with GWI. METHODS: Veterans with GWI (n = 37) and healthy control Gulf War Veterans (n = 25) provided blood samples before and after 30-min of cycling at 70% of age-pred …
OBJECTIVES: To investigate whether PEM is meditated by gene expression in Veterans with GWI. METHODS: Veterans with GWI (n = 3 …
Altered immune pathway activity under exercise challenge in Gulf War Illness: an exploratory analysis.
Broderick G, Ben-Hamo R, Vashishtha S, Efroni S, Nathanson L, Barnes Z, Fletcher MA, Klimas N. Broderick G, et al. Brain Behav Immun. 2013 Feb;28:159-69. doi: 10.1016/j.bbi.2012.11.007. Epub 2012 Nov 29. Brain Behav Immun. 2013. PMID: 23201588
Though potentially linked to the basic physiology of stress response we still have no clear understanding of Gulf War Illness (GWI), a debilitating illness presenting with a complex constellation of immune, endocrine and neurological symptoms. ...Affymetrix HG U133 …
Though potentially linked to the basic physiology of stress response we still have no clear understanding of Gulf War Illness …
Induction of distinct neuroinflammatory markers and gut dysbiosis by differential pyridostigmine bromide dosing in a chronic mouse model of GWI showing persistent exercise fatigue and cognitive impairment.
Kozlova EV, Carabelli B, Bishay AE, Liu R, Denys ME, Macbeth JC, Piamthai V, Crawford MS, McCole DF, Zur Nieden NI, Hsiao A, Curras-Collazo MC. Kozlova EV, et al. Life Sci. 2022 Jan 1;288:120153. doi: 10.1016/j.lfs.2021.120153. Epub 2021 Nov 18. Life Sci. 2022. PMID: 34801513 Free PMC article.
AIMS: To characterize neuroinflammatory and gut dysbiosis signatures that accompany exaggerated exercise fatigue and cognitive/mood deficits in a mouse model of Gulf War Illness (GWI). ...Animals were phenotypically evaluated as described in an accompa …
AIMS: To characterize neuroinflammatory and gut dysbiosis signatures that accompany exaggerated exercise fatigue and cognitive …
The effect of stress on the transcriptomes of circulating immune cells in patients with Gulf War Illness.
Van Booven D, Zarnowski O, Perez M, Sarria L, Collado F, Hansotia K, Riegle S, Finger T, Fletcher MA, Klimas NG, Nathanson L. Van Booven D, et al. Life Sci. 2021 Sep 15;281:119719. doi: 10.1016/j.lfs.2021.119719. Epub 2021 Jun 16. Life Sci. 2021. PMID: 34144055
AIMS: In an effort to gain further insight into the underlying mechanisms tied to disease onset and progression of Gulf War Illness (GWI), our team evaluated GWI patient response to stress utilizing RNA-Seq. ...These results provide a foundation for future research …
AIMS: In an effort to gain further insight into the underlying mechanisms tied to disease onset and progression of Gulf War Il …