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Items: 1 to 20 of 59


Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model.

Narayana JL, Mishra B, Lushnikova T, Golla RM, Wang G.

Biochim Biophys Acta Biomembr. 2019 Sep 1;1861(9):1592-1602. doi: 10.1016/j.bbamem.2019.07.012. Epub 2019 Jul 15.


Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens.

Mishra B, Lakshmaiah Narayana J, Lushnikova T, Wang X, Wang G.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13517-13522. doi: 10.1073/pnas.1821410116. Epub 2019 Jun 17.


Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37.

Wang G, Narayana JL, Mishra B, Zhang Y, Wang F, Wang C, Zarena D, Lushnikova T, Wang X.

Adv Exp Med Biol. 2019;1117:215-240. doi: 10.1007/978-981-13-3588-4_12. Review.


Amino Acid Composition Determines Peptide Activity Spectrum and Hot-Spot-Based Design of Merecidin.

Wang X, Mishra B, Lushnikova T, Narayana JL, Wang G.

Adv Biosyst. 2018 May;2(5). pii: 1700259. doi: 10.1002/adbi.201700259. Epub 2018 Mar 26.


Antimicrobial peptide LL-37 and its truncated forms, GI-20 and GF-17, exert spermicidal effects and microbicidal activity against Neisseria gonorrhoeae.

Kiattiburut W, Zhi R, Lee SG, Foo AC, Hickling DR, Keillor JW, Goto NK, Li W, Conlan W, Angel JB, Wang G, Tanphaichitr N.

Hum Reprod. 2018 Dec 1;33(12):2175-2183. doi: 10.1093/humrep/dey315.


Antibacterial, antifungal, anticancer activities and structural bioinformatics analysis of six naturally occurring temporins.

Mishra B, Wang X, Lushnikova T, Zhang Y, Golla RM, Narayana JL, Wang C, McGuire TR, Wang G.

Peptides. 2018 Aug;106:9-20. doi: 10.1016/j.peptides.2018.05.011. Epub 2018 May 26.


Cathelicidin-Derived Antimicrobial Peptides Inhibit Zika Virus Through Direct Inactivation and Interferon Pathway.

He M, Zhang H, Li Y, Wang G, Tang B, Zhao J, Huang Y, Zheng J.

Front Immunol. 2018 Apr 12;9:722. doi: 10.3389/fimmu.2018.00722. eCollection 2018.


The π Configuration of the WWW Motif of a Short Trp-Rich Peptide Is Critical for Targeting Bacterial Membranes, Disrupting Preformed Biofilms, and Killing Methicillin-Resistant Staphylococcus aureus.

Zarena D, Mishra B, Lushnikova T, Wang F, Wang G.

Biochemistry. 2017 Aug 8;56(31):4039-4043. doi: 10.1021/acs.biochem.7b00456. Epub 2017 Jul 26.


Individual and Combined Effects of Engineered Peptides and Antibiotics on Pseudomonas aeruginosa Biofilms.

Mishra B, Wang G.

Pharmaceuticals (Basel). 2017 Jun 25;10(3). pii: E58. doi: 10.3390/ph10030058.


Arginine-lysine positional swap of the LL-37 peptides reveals evolutional advantages of the native sequence and leads to bacterial probes.

Wang X, Junior JCB, Mishra B, Lushnikova T, Epand RM, Wang G.

Biochim Biophys Acta Biomembr. 2017 Aug;1859(8):1350-1361. doi: 10.1016/j.bbamem.2017.04.018. Epub 2017 Apr 24.


Host defense antimicrobial peptides as antibiotics: design and application strategies.

Mishra B, Reiling S, Zarena D, Wang G.

Curr Opin Chem Biol. 2017 Jun;38:87-96. doi: 10.1016/j.cbpa.2017.03.014. Epub 2017 Apr 8. Review.


Small molecule mimics of DFTamP1, a database designed anti-Staphylococcal peptide.

Dong Y, Lushnikova T, Golla RM, Wang X, Wang G.

Bioorg Med Chem. 2017 Feb 1;25(3):864-869. doi: 10.1016/j.bmc.2016.11.056. Epub 2016 Nov 30.


Design and surface immobilization of short anti-biofilm peptides.

Mishra B, Lushnikova T, Golla RM, Wang X, Wang G.

Acta Biomater. 2017 Feb;49:316-328. doi: 10.1016/j.actbio.2016.11.061. Epub 2016 Nov 30.


Collectins, H-ficolin and LL-37 reduce influence viral replication in human monocytes and modulate virus-induced cytokine production.

White MR, Tripathi S, Verma A, Kingma P, Takahashi K, Jensenius J, Thiel S, Wang G, Crouch EC, Hartshorn KL.

Innate Immun. 2017 Jan;23(1):77-88. doi: 10.1177/1753425916678470. Epub 2016 Nov 17.


Structure of the NPr:EINNtr Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems.

Strickland M, Stanley AM, Wang G, Botos I, Schwieters CD, Buchanan SK, Peterkofsky A, Tjandra N.

Structure. 2016 Dec 6;24(12):2127-2137. doi: 10.1016/j.str.2016.10.007. Epub 2016 Nov 10.


Insights into Antimicrobial Peptides from Spiders and Scorpions.

Wang X, Wang G.

Protein Pept Lett. 2016;23(8):707-21.


Anti-Staphylococcal Biofilm Effects of Human Cathelicidin Peptides.

Mishra B, Golla RM, Lau K, Lushnikova T, Wang G.

ACS Med Chem Lett. 2015 Dec 4;7(1):117-21. doi: 10.1021/acsmedchemlett.5b00433. eCollection 2016 Jan 14.

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