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Items: 1 to 20 of 61

1.

The affinity of MhuD for heme is consistent with a heme degrading function in vivo.

Thakuri B, Graves AB, Chao A, Johansen SL, Goulding CW, Liptak MD.

Metallomics. 2018 Sep 21. doi: 10.1039/c8mt00238j. [Epub ahead of print]

PMID:
30239544
2.

Functional plasticity of antibacterial EndoU toxins.

Michalska K, Quan Nhan D, Willett JLE, Stols LM, Eschenfeldt WH, Jones AM, Nguyen JY, Koskiniemi S, Low DA, Goulding CW, Joachimiak A, Hayes CS.

Mol Microbiol. 2018 Jun 20. doi: 10.1111/mmi.14007. [Epub ahead of print]

PMID:
29923643
3.

Introducing the new bacterial branch of the RNase A superfamily.

Cuthbert BJ, Burley KH, Goulding CW.

RNA Biol. 2018 Jan 2;15(1):9-12. doi: 10.1080/15476286.2017.1387710. Epub 2017 Nov 21.

PMID:
29099294
4.

Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.

Michalska K, Gucinski GC, Garza-Sánchez F, Johnson PM, Stols LM, Eschenfeldt WH, Babnigg G, Low DA, Goulding CW, Joachimiak A, Hayes CS.

Nucleic Acids Res. 2017 Sep 29;45(17):10306-10320. doi: 10.1093/nar/gkx700.

5.

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).

Kryshtafovych A, Albrecht R, Baslé A, Bule P, Caputo AT, Carvalho AL, Chao KL, Diskin R, Fidelis K, Fontes CMGA, Fredslund F, Gilbert HJ, Goulding CW, Hartmann MD, Hayes CS, Herzberg O, Hill JC, Joachimiak A, Kohring GW, Koning RI, Lo Leggio L, Mangiagalli M, Michalska K, Moult J, Najmudin S, Nardini M, Nardone V, Ndeh D, Nguyen TH, Pintacuda G, Postel S, van Raaij MJ, Roversi P, Shimon A, Singh AK, Sundberg EJ, Tars K, Zitzmann N, Schwede T.

Proteins. 2018 Mar;86 Suppl 1:27-50. doi: 10.1002/prot.25392. Epub 2017 Oct 16.

6.

From B to A: making an essential cofactor in a human parasite.

Morrissette NS, Goulding CW.

Biochem J. 2017 Aug 30;474(18):3089-3092. doi: 10.1042/BCJ20170446.

PMID:
28860337
7.

Protein engineering: Redirecting membrane machinery.

Burley K, Goulding CW.

Nat Chem Biol. 2017 Aug 18;13(9):927-928. doi: 10.1038/nchembio.2451. No abstract available.

PMID:
28820876
8.

The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily.

Batot G, Michalska K, Ekberg G, Irimpan EM, Joachimiak G, Jedrzejczak R, Babnigg G, Hayes CS, Joachimiak A, Goulding CW.

Nucleic Acids Res. 2017 May 19;45(9):5013-5025. doi: 10.1093/nar/gkx230.

9.

Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes.

Costa DL, Namasivayam S, Amaral EP, Arora K, Chao A, Mittereder LR, Maiga M, Boshoff HI, Barry CE 3rd, Goulding CW, Andrade BB, Sher A.

MBio. 2016 Oct 25;7(5). pii: e01675-16. doi: 10.1128/mBio.01675-16.

10.

Progress toward the Development of a NEAT Protein Vaccine for Anthrax Disease.

Balderas MA, Nguyen CT, Terwilliger A, Keitel WA, Iniguez A, Torres R, Palacios F, Goulding CW, Maresso AW.

Infect Immun. 2016 Nov 18;84(12):3408-3422. Print 2016 Dec.

11.

Unraveling the essential role of CysK in CDI toxin activation.

Johnson PM, Beck CM, Morse RP, Garza-Sánchez F, Low DA, Hayes CS, Goulding CW.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9792-7. doi: 10.1073/pnas.1607112113. Epub 2016 Aug 16.

12.

Functional Diversity of Cytotoxic tRNase/Immunity Protein Complexes from Burkholderia pseudomallei.

Johnson PM, Gucinski GC, Garza-Sánchez F, Wong T, Hung LW, Hayes CS, Goulding CW.

J Biol Chem. 2016 Sep 9;291(37):19387-400. doi: 10.1074/jbc.M116.736074. Epub 2016 Jul 20.

13.

Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration.

Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, Goulding CW, Chazin WJ, Skaar EP, Raffatellu M.

Cell Host Microbe. 2016 Jun 8;19(6):814-25. doi: 10.1016/j.chom.2016.05.005.

14.

Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation.

Matsui T, Nambu S, Goulding CW, Takahashi S, Fujii H, Ikeda-Saito M.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3779-84. doi: 10.1073/pnas.1523333113. Epub 2016 Mar 22.

15.

Diversification of β-Augmentation Interactions between CDI Toxin/Immunity Proteins.

Morse RP, Willett JL, Johnson PM, Zheng J, Credali A, Iniguez A, Nowick JS, Hayes CS, Goulding CW.

J Mol Biol. 2015 Nov 20;427(23):3766-84. doi: 10.1016/j.jmb.2015.09.020. Epub 2015 Oct 9.

16.

Contact-Dependent Growth Inhibition (CDI) and CdiB/CdiA Two-Partner Secretion Proteins.

Willett JL, Ruhe ZC, Goulding CW, Low DA, Hayes CS.

J Mol Biol. 2015 Nov 20;427(23):3754-65. doi: 10.1016/j.jmb.2015.09.010. Epub 2015 Sep 24. Review.

17.

The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis.

Chim N, Torres R, Liu Y, Capri J, Batot G, Whitelegge JP, Goulding CW.

Chem Biol. 2015 Aug 20;22(8):1098-107. doi: 10.1016/j.chembiol.2015.07.013. Epub 2015 Aug 13.

18.

Fe(2+) substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization.

Behera RK, Torres R, Tosha T, Bradley JM, Goulding CW, Theil EC.

J Biol Inorg Chem. 2015 Sep;20(6):957-69. doi: 10.1007/s00775-015-1279-x. Epub 2015 Jul 23.

19.

The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58.

Tan K, Johnson PM, Stols L, Boubion B, Eschenfeldt W, Babnigg G, Hayes CS, Joachimiak A, Goulding CW.

Acta Crystallogr F Struct Biol Commun. 2015 Jun;71(Pt 6):702-9. doi: 10.1107/S2053230X15006585. Epub 2015 May 20.

20.

Crystallographic and spectroscopic insights into heme degradation by Mycobacterium tuberculosis MhuD.

Graves AB, Morse RP, Chao A, Iniguez A, Goulding CW, Liptak MD.

Inorg Chem. 2014 Jun 16;53(12):5931-40. doi: 10.1021/ic500033b. Epub 2014 Jun 5.

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