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Potential role of α-lipoic acid and Ginkgo biloba against silver nanoparticles-induced neuronal apoptosis and blood-brain barrier impairments in rats.

Lebda MA, Sadek KM, Tohamy HG, Abouzed TK, Shukry M, Umezawa M, El-Sayed YS.

Life Sci. 2018 Oct 7. pii: S0024-3205(18)30628-3. doi: 10.1016/j.lfs.2018.10.011. [Epub ahead of print]


Ginkgolide B promotes neuronal differentiation through the Wnt/β-catenin pathway in neural stem cells of the postnatal mammalian subventricular zone.

Li MY, Chang CT, Han YT, Liao CP, Yu JY, Wang TW.

Sci Rep. 2018 Oct 8;8(1):14947. doi: 10.1038/s41598-018-32960-8.


Role of Ginkgo biloba extract as an adjunctive treatment of elderly patients with depression and on the expression of serum S100B.

Dai CX, Hu CC, Shang YS, Xie J.

Medicine (Baltimore). 2018 Sep;97(39):e12421. doi: 10.1097/MD.0000000000012421.


Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation.

Yu WB, Cao L, Zhao YY, Xiao W, Xiao BG.

Mol Med Rep. 2018 Sep 4. doi: 10.3892/mmr.2018.9450. [Epub ahead of print]


Ginkgo biloba L. (Ginkgoaceae) Leaf Extract Medications From Different Providers Exhibit Differential Functional Effects on Mouse Frontal Cortex Neuronal Networks.

Bader BM, Jügelt K, Schultz L, Schroeder OH.

Front Pharmacol. 2018 Aug 3;9:848. doi: 10.3389/fphar.2018.00848. eCollection 2018.


Standardized Ginkgo biloba extract EGb 761® attenuates early brain injury following subarachnoid hemorrhage via suppressing neuronal apoptosis through the activation of Akt signaling.

Yu T, Fan Y, Xu Y, Xu L, Xu G, Cao F, Jiang H.

Biomed Pharmacother. 2018 Nov;107:329-337. doi: 10.1016/j.biopha.2018.08.012. Epub 2018 Aug 8.


The Acute and Chronic Cognitive and Cerebral Blood Flow Effects of a Sideritis scardica (Greek Mountain Tea) Extract: A Double Blind, Randomized, Placebo Controlled, Parallel Groups Study in Healthy Humans.

Wightman EL, Jackson PA, Khan J, Forster J, Heiner F, Feistel B, Suarez CG, Pischel I, Kennedy DO.

Nutrients. 2018 Jul 24;10(8). pii: E955. doi: 10.3390/nu10080955.


Ginkgolide B ameliorates NLRP3 inflammasome activation after hypoxic-ischemic brain injury in the neonatal male rat.

Chen A, Xu Y, Yuan J.

Int J Dev Neurosci. 2018 Oct;69:106-111. doi: 10.1016/j.ijdevneu.2018.07.004. Epub 2018 Jul 17.


Ginkgo biloba extract and its diterpene ginkgolide constituents ameliorate the metabolic disturbances caused by recombinant tissue plasminogen activator in rat prefrontal cortex.

Chen Z, Bai S, Hu Q, Shen P, Wang T, Liang Z, Wang W, Qi X, Xie P.

Neuropsychiatr Dis Treat. 2018 Jul 4;14:1755-1772. doi: 10.2147/NDT.S167448. eCollection 2018.


Ginkgo biloba Extract EGb 761 and Its Specific Components Elicit Protective Protein Clearance Through the Autophagy-Lysosomal Pathway in Tau-Transgenic Mice and Cultured Neurons.

Qin Y, Zhang Y, Tomic I, Hao W, Menger MD, Liu C, Fassbender K, Liu Y.

J Alzheimers Dis. 2018;65(1):243-263. doi: 10.3233/JAD-180426.


[Role of Ginkgo biloba extract in regulating 5-hydroxytrytamine and its receptor in heart failure mice].

Liu MY, Zhang LJ.

Zhonghua Yi Xue Za Zhi. 2018 Jul 3;98(25):2024-2029. doi: 10.3760/cma.j.issn.0376-2491.2018.25.012. Chinese.


Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke.

Zhang Y, Liu J, Yang B, Zheng Y, Yao M, Sun M, Xu L, Lin C, Chang D, Tian F.

Front Pharmacol. 2018 May 16;9:518. doi: 10.3389/fphar.2018.00518. eCollection 2018.


By Activating Akt/eNOS Bilobalide B Inhibits Autophagy and Promotes Angiogenesis Following Focal Cerebral Ischemia Reperfusion.

Zheng Y, Wu Z, Yi F, Orange M, Yao M, Yang B, Liu J, Zhu H.

Cell Physiol Biochem. 2018;47(2):604-616. doi: 10.1159/000490016. Epub 2018 May 22.


Metabolite-related antidepressant action of diterpene ginkgolides in the prefrontal cortex.

Hu Q, Shen P, Bai S, Dong M, Liang Z, Chen Z, Wang W, Wang H, Gui S, Li P, Xie P.

Neuropsychiatr Dis Treat. 2018 Apr 13;14:999-1011. doi: 10.2147/NDT.S161351. eCollection 2018.


Tnfrsf12a-Mediated Atherosclerosis Signaling and Inflammatory Response as a Common Protection Mechanism of Shuxuening Injection Against Both Myocardial and Cerebral Ischemia-Reperfusion Injuries.

Lyu M, Cui Y, Zhao T, Ning Z, Ren J, Jin X, Fan G, Zhu Y.

Front Pharmacol. 2018 Apr 6;9:312. doi: 10.3389/fphar.2018.00312. eCollection 2018.


Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling.

Zhang W, Song JK, Yan R, Li L, Xiao ZY, Zhou WX, Wang ZZ, Xiao W, Du GH.

Acta Pharmacol Sin. 2018 Mar 15. doi: 10.1038/aps.2017.149. [Epub ahead of print]


Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer's Disease.

Stockburger C, Eckert S, Eckert GP, Friedland K, Müller WE.

J Alzheimers Dis. 2018;64(s1):S455-S467. doi: 10.3233/JAD-179915.


[Protective effects of Ginkgo Terpene Lactones Meglumine Injection on focal cerebral ischemia in rats].

Luo YP, Zhang H, Hu HF, Cao ZY, Zhang XZ, Cao L, Wang ZZ, Xiao W.

Zhongguo Zhong Yao Za Zhi. 2017 Dec;42(24):4733-4737. doi: 10.19540/j.cnki.cjcmm.2017.0209. Chinese.


Botanicals as Modulators of Neuroplasticity: Focus on BDNF.

Sangiovanni E, Brivio P, Dell'Agli M, Calabrese F.

Neural Plast. 2017;2017:5965371. doi: 10.1155/2017/5965371. Epub 2017 Dec 31. Review.


[Cerebral insulin resistance: current concepts of the pathogenesis and possible therapeutic strategies].

Esin RG, Khairullin IK, Esin OR.

Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):92-95. doi: 10.17116/jnevro20181181192-95. Russian.


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