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Items: 1 to 20 of 71


Protective role of the lipid phosphatase Fig4 in the adult nervous system.

Mironova YA, Lin JP, Kalinski AL, Huffman LD, Lenk GM, Havton LA, Meisler MH, Giger RJ.

Hum Mol Genet. 2018 Jul 15;27(14):2443-2453. doi: 10.1093/hmg/ddy145.


PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors.

Zhao XF, Kohen R, Parent R, Duan Y, Fisher GL, Korn MJ, Ji L, Wan G, Jin J, Püschel AW, Dolan DF, Parent JM, Corfas G, Murphy GG, Giger RJ.

Cell Rep. 2018 Jan 9;22(2):456-470. doi: 10.1016/j.celrep.2017.12.044.


Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif.

Pinskey JM, Franks NE, McMellen AN, Giger RJ, Allen BL.

J Biol Chem. 2017 Sep 15;292(37):15192-15204. doi: 10.1074/jbc.M117.783845. Epub 2017 Jun 30.


Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice.

Sozmen EG, Rosenzweig S, Llorente IL, DiTullio DJ, Machnicki M, Vinters HV, Havton LA, Giger RJ, Hinman JD, Carmichael ST.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8453-E8462. doi: 10.1073/pnas.1615322113. Epub 2016 Dec 12.


Reassembly of Excitable Domains after CNS Axon Regeneration.

Marin MA, de Lima S, Gilbert HY, Giger RJ, Benowitz L, Rasband MN.

J Neurosci. 2016 Aug 31;36(35):9148-60. doi: 10.1523/JNEUROSCI.1747-16.2016.


An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK.

Hao Y, Frey E, Yoon C, Wong H, Nestorovski D, Holzman LB, Giger RJ, DiAntonio A, Collins C.

Elife. 2016 Jun 7;5. pii: e14048. doi: 10.7554/eLife.14048.


Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons.

Wehner AB, Abdesselem H, Dickendesher TL, Imai F, Yoshida Y, Giger RJ, Pierchala BA.

Development. 2016 May 1;143(9):1560-70. doi: 10.1242/dev.134627.


PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms.

Mironova YA, Lenk GM, Lin JP, Lee SJ, Twiss JL, Vaccari I, Bolino A, Havton LA, Min SH, Abrams CS, Shrager P, Meisler MH, Giger RJ.

Elife. 2016 Mar 23;5. pii: e13023. doi: 10.7554/eLife.13023.


Stable biomarker for plastic microglia.

Segal BM, Giger RJ.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3130-2. doi: 10.1073/pnas.1601669113. Epub 2016 Mar 10. No abstract available.


Inside Out: Core Network of Transcription Factors Drives Axon Regeneration.

Yoon C, Giger RJ.

Neuron. 2016 Mar 2;89(5):881-4. doi: 10.1016/j.neuron.2016.02.022.


Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene.

Lenk GM, Frei CM, Miller AC, Wallen RC, Mironova YA, Giger RJ, Meisler MH.

Hum Mol Genet. 2016 Jan 15;25(2):340-7. doi: 10.1093/hmg/ddv480. Epub 2015 Nov 24.


Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.

Carbajal KS, Mironova Y, Ulrich-Lewis JT, Kulkarni D, Grifka-Walk HM, Huber AK, Shrager P, Giger RJ, Segal BM.

J Immunol. 2015 Sep 15;195(6):2552-9. doi: 10.4049/jimmunol.1501097. Epub 2015 Aug 3.


Insights into the physiological role of CNS regeneration inhibitors.

Baldwin KT, Giger RJ.

Front Mol Neurosci. 2015 Jun 11;8:23. doi: 10.3389/fnmol.2015.00023. eCollection 2015. Review.


Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration.

Baldwin KT, Carbajal KS, Segal BM, Giger RJ.

Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2581-6. doi: 10.1073/pnas.1423221112. Epub 2015 Feb 9.


Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

Duan Y, Wang SH, Song J, Mironova Y, Ming GL, Kolodkin AL, Giger RJ.

Elife. 2014 Oct 14;3. doi: 10.7554/eLife.04390.


Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy.

Vaccari I, Carbone A, Previtali SC, Mironova YA, Alberizzi V, Noseda R, Rivellini C, Bianchi F, Del Carro U, D'Antonio M, Lenk GM, Wrabetz L, Giger RJ, Meisler MH, Bolino A.

Hum Mol Genet. 2015 Jan 15;24(2):383-96. doi: 10.1093/hmg/ddu451. Epub 2014 Sep 3.


Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1.

Murthy R, Kim J, Sun X, Giger RJ, Fink DJ, Mata M.

Mol Brain. 2013 Jul 6;6:30. doi: 10.1186/1756-6606-6-30.


Where no synapses go: gatekeepers of circuit remodeling and synaptic strength.

Mironova YA, Giger RJ.

Trends Neurosci. 2013 Jun;36(6):363-73. doi: 10.1016/j.tins.2013.04.003. Epub 2013 May 2. Review.


LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.

Stiles TL, Dickendesher TL, Gaultier A, Fernandez-Castaneda A, Mantuano E, Giger RJ, Gonias SL.

J Cell Sci. 2013 Jan 1;126(Pt 1):209-20. doi: 10.1242/jcs.113191. Epub 2012 Nov 6.

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