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Items: 1 to 20 of 45


Centriolar satellites are acentriolar assemblies of centrosomal proteins.

Quarantotti V, Chen JX, Tischer J, Gonzalez Tejedo C, Papachristou EK, D'Santos CS, Kilmartin JV, Miller ML, Gergely F.

EMBO J. 2019 Jul 15;38(14):e101082. doi: 10.15252/embj.2018101082. Epub 2019 Jun 3.


Centriolar satellites are acentriolar assemblies of centrosomal proteins.

Quarantotti V, Chen JX, Tischer J, Gonzalez Tejedo C, Papachristou EK, D'Santos CS, Kilmartin JV, Miller ML, Gergely F.

EMBO J. 2019 Jun 3. pii: e101082. doi: 10.15252/embj.2018101082. [Epub ahead of print]


Anti-mitotic therapies in cancer.

Tischer J, Gergely F.

J Cell Biol. 2019 Jan 7;218(1):10-11. doi: 10.1083/jcb.201808077. Epub 2018 Dec 13. No abstract available.


Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis.

Stojic L, Lun ATL, Mangei J, Mascalchi P, Quarantotti V, Barr AR, Bakal C, Marioni JC, Gergely F, Odom DT.

Nucleic Acids Res. 2018 Jul 6;46(12):5950-5966. doi: 10.1093/nar/gky437.


Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.

Joseph N, Al-Jassar C, Johnson CM, Andreeva A, Barnabas DD, Freund SMV, Gergely F, van Breugel M.

Cell Rep. 2018 May 29;23(9):2805-2818. doi: 10.1016/j.celrep.2018.04.100.


Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix.

Burgess SG, Mukherjee M, Sabir S, Joseph N, Gutiérrez-Caballero C, Richards MW, Huguenin-Dezot N, Chin JW, Kennedy EJ, Pfuhl M, Royle SJ, Gergely F, Bayliss R.

EMBO J. 2018 Apr 13;37(8). pii: e97902. doi: 10.15252/embj.201797902. Epub 2018 Mar 6.


Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication.

Chavali PL, Stojic L, Meredith LW, Joseph N, Nahorski MS, Sanford TJ, Sweeney TR, Krishna BA, Hosmillo M, Firth AE, Bayliss R, Marcelis CL, Lindsay S, Goodfellow I, Woods CG, Gergely F.

Science. 2017 Jul 7;357(6346):83-88. doi: 10.1126/science.aam9243. Epub 2017 Jun 1.


A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer.

Chavali PL, Chandrasekaran G, Barr AR, Tátrai P, Taylor C, Papachristou EK, Woods CG, Chavali S, Gergely F.

Nat Commun. 2016 Mar 18;7:11005. doi: 10.1038/ncomms11005.


Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions.

Stojic L, Niemczyk M, Orjalo A, Ito Y, Ruijter AE, Uribe-Lewis S, Joseph N, Weston S, Menon S, Odom DT, Rinn J, Gergely F, Murrell A.

Nat Commun. 2016 Feb 2;7:10406. doi: 10.1038/ncomms10406.


Hitting the brakes: targeting microtubule motors in cancer.

Chandrasekaran G, Tátrai P, Gergely F.

Br J Cancer. 2015 Sep 1;113(5):693-8. doi: 10.1038/bjc.2015.264. Epub 2015 Jul 16. Review.


Tackling centrosome biology through gene targeting in chicken B cells.

Chavali PL, Gergely F.

Methods Cell Biol. 2015;129:83-102. doi: 10.1016/bs.mcb.2015.03.008. Epub 2015 May 27.


Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly.

Burgess SG, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, Gergely F, Bayliss R.

PLoS Genet. 2015 Jul 2;11(7):e1005345. doi: 10.1371/journal.pgen.1005345. eCollection 2015 Jul.


Centrosomes and mitotic spindle poles: a recent liaison?

Chavali PL, Peset I, Gergely F.

Biochem Soc Trans. 2015 Feb;43(1):13-8. doi: 10.1042/BST20140269.


Small organelle, big responsibility: the role of centrosomes in development and disease.

Chavali PL, Pütz M, Gergely F.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). pii: 20130468. doi: 10.1098/rstb.2013.0468. Review.


Loss of centrioles causes chromosomal instability in vertebrate somatic cells.

Sir JH, Pütz M, Daly O, Morrison CG, Dunning M, Kilmartin JV, Gergely F.

J Cell Biol. 2013 Dec 9;203(5):747-56. doi: 10.1083/jcb.201309038. Epub 2013 Dec 2.


Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes.

Watts CA, Richards FM, Bender A, Bond PJ, Korb O, Kern O, Riddick M, Owen P, Myers RM, Raff J, Gergely F, Jodrell DI, Ley SV.

Chem Biol. 2013 Nov 21;20(11):1399-410. doi: 10.1016/j.chembiol.2013.09.012. Epub 2013 Oct 24.


Cilia born out of shock and stress.

Chavali PL, Gergely F.

EMBO J. 2013 Nov 27;32(23):3011-3. doi: 10.1038/emboj.2013.241. Epub 2013 Nov 1. No abstract available.


Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells.

Inanç B, Pütz M, Lalor P, Dockery P, Kuriyama R, Gergely F, Morrison CG.

Mol Biol Cell. 2013 Sep;24(17):2645-54. doi: 10.1091/mbc.E13-03-0149. Epub 2013 Jul 17.


Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B, Del Castillo Velasco-Herrera M, Edwards A, van der Weyden L, Yang F; Sanger Mouse Genetics Project, Ramirez-Solis R, Estabel J, Gallagher FA, Logan DW, Arends MJ, Tsang SH, Mahajan VB, Scudamore CL, White JK, Jackson SP, Gergely F, Adams DJ.

PLoS Genet. 2012;8(11):e1003022. doi: 10.1371/journal.pgen.1003022. Epub 2012 Nov 15.


Casein kinase I delta controls centrosome positioning during T cell activation.

Zyss D, Ebrahimi H, Gergely F.

J Cell Biol. 2011 Nov 28;195(5):781-97. doi: 10.1083/jcb.201106025.

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