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Items: 1 to 20 of 63

1.

The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.

Manav MC, Turnbull KJ, Jurėnas D, Garcia-Pino A, Gerdes K, Brodersen DE.

Structure. 2019 Nov 5;27(11):1675-1685.e3. doi: 10.1016/j.str.2019.08.008. Epub 2019 Sep 5.

PMID:
31495532
2.

The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis.

Van Nerom K, Tamman H, Takada H, Hauryliuk V, Garcia-Pino A.

Acta Crystallogr F Struct Biol Commun. 2019 Aug 1;75(Pt 8):561-569. doi: 10.1107/S2053230X19010628. Epub 2019 Aug 2.

PMID:
31397328
3.

Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.

Sigoillot M, Overtus M, Grodecka M, Scholl D, Garcia-Pino A, Laeremans T, He L, Pardon E, Hildebrandt E, Urbatsch I, Steyaert J, Riordan JR, Govaerts C.

Nat Commun. 2019 Jun 14;10(1):2636. doi: 10.1038/s41467-019-10714-y.

4.

A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.

Talavera A, Tamman H, Ainelo A, Konijnenberg A, Hadži S, Sobott F, Garcia-Pino A, Hõrak R, Loris R.

Nat Commun. 2019 Feb 27;10(1):972. doi: 10.1038/s41467-019-08865-z.

5.

Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.

Jurėnas D, Van Melderen L, Garcia-Pino A.

Nat Chem Biol. 2019 Mar;15(3):285-294. doi: 10.1038/s41589-018-0216-z. Epub 2019 Feb 4.

PMID:
30718814
6.

Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain.

Ronneau S, Caballero-Montes J, Coppine J, Mayard A, Garcia-Pino A, Hallez R.

Nucleic Acids Res. 2019 Jan 25;47(2):843-854. doi: 10.1093/nar/gky1201.

7.

Reply to Holden and Errington, "Type II Toxin-Antitoxin Systems and Persister Cells".

Goormaghtigh F, Fraikin N, Putrinš M, Hauryliuk V, Garcia-Pino A, Udekwu K, Tenson T, Kaldalu N, Van Melderen L.

MBio. 2018 Sep 25;9(5). pii: e01838-18. doi: 10.1128/mBio.01838-18. No abstract available.

8.

A molecular mechanism for Wnt ligand-specific signaling.

Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR, Garcia-Pino A, Vanhollebeke B.

Science. 2018 Aug 17;361(6403). pii: eaat1178. doi: 10.1126/science.aat1178. Epub 2018 Jul 19.

PMID:
30026314
9.

Crystallization and X-ray analysis of all of the players in the autoregulation of the ataRT toxin-antitoxin system.

Jurėnas D, Van Melderen L, Garcia-Pino A.

Acta Crystallogr F Struct Biol Commun. 2018 Jul 1;74(Pt 7):391-401. doi: 10.1107/S2053230X18007914. Epub 2018 Jun 26.

PMID:
29969102
10.

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells.

Goormaghtigh F, Fraikin N, Putrinš M, Hallaert T, Hauryliuk V, Garcia-Pino A, Sjödin A, Kasvandik S, Udekwu K, Tenson T, Kaldalu N, Van Melderen L.

MBio. 2018 Jun 12;9(3). pii: e00640-18. doi: 10.1128/mBio.00640-18.

11.

ARE-mediated decay controls gene expression and cellular metabolism upon oxygen variations.

de Toeuf B, Soin R, Nazih A, Dragojevic M, Jurėnas D, Delacourt N, Vo Ngoc L, Garcia-Pino A, Kruys V, Gueydan C.

Sci Rep. 2018 Mar 26;8(1):5211. doi: 10.1038/s41598-018-23551-8.

12.

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.

Talavera A, Hendrix J, Versées W, Jurėnas D, Van Nerom K, Vandenberk N, Singh RK, Konijnenberg A, De Gieter S, Castro-Roa D, Barth A, De Greve H, Sobott F, Hofkens J, Zenkin N, Loris R, Garcia-Pino A.

Sci Adv. 2018 Mar 14;4(3):eaap9714. doi: 10.1126/sciadv.aap9714. eCollection 2018 Mar.

13.

Messing up translation from the start: How AtaT inhibits translation initiation in E. coli.

Van Melderen L, Jurenas D, Garcia-Pino A.

RNA Biol. 2018 Mar 4;15(3):303-307. doi: 10.1080/15476286.2017.1391439. Epub 2018 Jan 30.

14.

Novel toxins from type II toxin-antitoxin systems with acetyltransferase activity.

Jurėnas D, Garcia-Pino A, Van Melderen L.

Plasmid. 2017 Sep;93:30-35. doi: 10.1016/j.plasmid.2017.08.005. Epub 2017 Sep 20. Review.

15.

Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.

Talavera A, Tamman H, Ainelo A, Hadǽi S, Garcia-Pino A, Hõrak R, Konijnenberg A, Loris R.

Acta Crystallogr F Struct Biol Commun. 2017 Aug 1;73(Pt 8):455-462. doi: 10.1107/S2053230X17009438. Epub 2017 Jul 26.

16.

AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet.

Jurėnas D, Chatterjee S, Konijnenberg A, Sobott F, Droogmans L, Garcia-Pino A, Van Melderen L.

Nat Chem Biol. 2017 Jun;13(6):640-646. doi: 10.1038/nchembio.2346. Epub 2017 Apr 3.

17.

Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.

Hadži S, Garcia-Pino A, Haesaerts S, Jurenas D, Gerdes K, Lah J, Loris R.

Nucleic Acids Res. 2017 May 5;45(8):4972-4983. doi: 10.1093/nar/gkx138.

18.

Structural Characterization of Monomeric/Dimeric State of p59fyn SH2 Domain.

Huculeci R, Kieken F, Garcia-Pino A, Buts L, van Nuland N, Lenaerts T.

Methods Mol Biol. 2017;1555:257-267. doi: 10.1007/978-1-4939-6762-9_14.

PMID:
28092037
19.

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.

Egea-Jimenez AL, Gallardo R, Garcia-Pino A, Ivarsson Y, Wawrzyniak AM, Kashyap R, Loris R, Schymkowitz J, Rousseau F, Zimmermann P.

Nat Commun. 2016 Jul 8;7:12101. doi: 10.1038/ncomms12101.

20.

An intrinsically disordered entropic switch determines allostery in Phd-Doc regulation.

Garcia-Pino A, De Gieter S, Talavera A, De Greve H, Efremov RG, Loris R.

Nat Chem Biol. 2016 Jul;12(7):490-6. doi: 10.1038/nchembio.2078. Epub 2016 May 2.

PMID:
27159580

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