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Items: 1 to 20 of 197


Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography.

Park D, Lara-Tejero M, Waxham MN, Li W, Hu B, Galán JE, Liu J.

Elife. 2018 Oct 3;7. pii: e39514. doi: 10.7554/eLife.39514.


Peptidoglycan editing by a specific LD-transpeptidase controls the muramidase-dependent secretion of typhoid toxin.

Geiger T, Pazos M, Lara-Tejero M, Vollmer W, Galán JE.

Nat Microbiol. 2018 Nov;3(11):1243-1254. doi: 10.1038/s41564-018-0248-x. Epub 2018 Sep 24.


Salmonella stimulates pro-inflammatory signalling through p21-activated kinases bypassing innate immune receptors.

Sun H, Kamanova J, Lara-Tejero M, Galán JE.

Nat Microbiol. 2018 Oct;3(10):1122-1130. doi: 10.1038/s41564-018-0246-z. Epub 2018 Sep 17.


A protein secreted by the Salmonella type III secretion system controls needle filament assembly.

Kato J, Dey S, Soto JE, Butan C, Wilkinson MC, De Guzman RN, Galan JE.

Elife. 2018 Jul 17;7. pii: e35886. doi: 10.7554/eLife.35886.


Protein-Injection Machines in Bacteria.

Galán JE, Waksman G.

Cell. 2018 Mar 8;172(6):1306-1318. doi: 10.1016/j.cell.2018.01.034. Review.


Decoding a Salmonella Typhi Regulatory Network that Controls Typhoid Toxin Expression within Human Cells.

Fowler CC, Galán JE.

Cell Host Microbe. 2018 Jan 10;23(1):65-76.e6. doi: 10.1016/j.chom.2017.12.001.


Author Correction: Evolution of host adaptation in the Salmonella typhoid toxin.

Gao X, Deng L, Stack G, Yu H, Chen X, Naito-Matsui Y, Varki A, Galán JE.

Nat Microbiol. 2017 Dec;2(12):1697. doi: 10.1038/s41564-017-0070-x.


Evolution of host adaptation in the Salmonella typhoid toxin.

Gao X, Deng L, Stack G, Yu H, Chen X, Naito-Matsui Y, Varki A, Galán JE.

Nat Microbiol. 2017 Dec;2(12):1592-1599. doi: 10.1038/s41564-017-0033-2. Epub 2017 Oct 9. Erratum in: Nat Microbiol. 2017 Dec;2(12 ):1697.


Salmonella enterica serovar-specific transcriptional reprogramming of infected cells.

Hannemann S, Galán JE.

PLoS Pathog. 2017 Jul 24;13(7):e1006532. doi: 10.1371/journal.ppat.1006532. eCollection 2017 Jul.


Taking control: Hijacking of Rab GTPases by intracellular bacterial pathogens.

Spanò S, Galán JE.

Small GTPases. 2018 Mar 4;9(1-2):182-191. doi: 10.1080/21541248.2017.1336192. Epub 2017 Jul 5. Review.


Metabolic and fitness determinants for in vitro growth and intestinal colonization of the bacterial pathogen Campylobacter jejuni.

Gao B, Vorwerk H, Huber C, Lara-Tejero M, Mohr J, Goodman AL, Eisenreich W, Galán JE, Hofreuter D.

PLoS Biol. 2017 May 19;15(5):e2001390. doi: 10.1371/journal.pbio.2001390. eCollection 2017 May.


Visualization and characterization of individual type III protein secretion machines in live bacteria.

Zhang Y, Lara-Tejero M, Bewersdorf J, Galán JE.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6098-6103. doi: 10.1073/pnas.1705823114. Epub 2017 May 22.


In Situ Molecular Architecture of the Salmonella Type III Secretion Machine.

Hu B, Lara-Tejero M, Kong Q, Galán JE, Liu J.

Cell. 2017 Mar 9;168(6):1065-1074.e10. doi: 10.1016/j.cell.2017.02.022.


Emerging insights into the biology of typhoid toxin.

Fowler CC, Chang SJ, Gao X, Geiger T, Stack G, Galán JE.

Curr Opin Microbiol. 2017 Feb;35:70-77. doi: 10.1016/j.mib.2017.01.012. Epub 2017 Feb 16. Review.


Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus.

Dietsche T, Tesfazgi Mebrhatu M, Brunner MJ, Abrusci P, Yan J, Franz-Wachtel M, Schärfe C, Zilkenat S, Grin I, Galán JE, Kohlbacher O, Lea S, Macek B, Marlovits TC, Robinson CV, Wagner S.

PLoS Pathog. 2016 Dec 15;12(12):e1006071. doi: 10.1371/journal.ppat.1006071. eCollection 2016 Dec.


Receptor-Mediated Sorting of Typhoid Toxin during Its Export from Salmonella Typhi-Infected Cells.

Chang SJ, Song J, Galán JE.

Cell Host Microbe. 2016 Nov 9;20(5):682-689. doi: 10.1016/j.chom.2016.10.005.


Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.

Galán JE.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6338-44. doi: 10.1073/pnas.1606335113. Epub 2016 May 24. Review.


The Salmonella Effector Protein SopA Modulates Innate Immune Responses by Targeting TRIM E3 Ligase Family Members.

Kamanova J, Sun H, Lara-Tejero M, Galán JE.

PLoS Pathog. 2016 Apr 8;12(4):e1005552. doi: 10.1371/journal.ppat.1005552. eCollection 2016 Apr.


A Family of Salmonella Type III Secretion Effector Proteins Selectively Targets the NF-κB Signaling Pathway to Preserve Host Homeostasis.

Sun H, Kamanova J, Lara-Tejero M, Galán JE.

PLoS Pathog. 2016 Mar 2;12(3):e1005484. doi: 10.1371/journal.ppat.1005484. eCollection 2016 Mar.


Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi.

Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, Yarovinsky F.

Cell. 2016 Feb 25;164(5):827-8. doi: 10.1016/j.cell.2016.02.015. No abstract available.

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