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Items: 1 to 20 of 44

1.

Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages.

Smith TKT, Kahiel Z, LeBlond ND, Ghorbani P, Farah E, Al-Awosi R, Cote M, Gadde S, Fullerton MD.

Molecules. 2019 Oct 18;24(20). pii: E3751. doi: 10.3390/molecules24203751.

2.

Maternal diet-induced obesity alters muscle mitochondrial function in offspring without changing insulin sensitivity.

McMurray F, MacFarlane M, Kim K, Patten DA, Wei-LaPierre L, Fullerton MD, Harper ME.

FASEB J. 2019 Dec;33(12):13515-13526. doi: 10.1096/fj.201901150R. Epub 2019 Oct 3.

PMID:
31581846
3.

A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells.

Stewart CM, Dorion SS, Ottenbrite MAF, LeBlond ND, Smith TKT, Qiu S, Fullerton MD, Kobasa D, Côté M.

Viruses. 2019 Mar 1;11(3). pii: E206. doi: 10.3390/v11030206.

4.

AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles.

Losier TT, Akuma M, McKee-Muir OC, LeBlond ND, Suk Y, Alsaadi RM, Guo Z, Reshke R, Sad S, Campbell-Valois FX, Gibbings DJ, Fullerton MD, Russell RC.

Cell Rep. 2019 Feb 19;26(8):2150-2165.e5. doi: 10.1016/j.celrep.2019.01.062.

5.

Interleukin-18 up-regulates amino acid transporters and facilitates amino acid-induced mTORC1 activation in natural killer cells.

Almutairi SM, Ali AK, He W, Yang DS, Ghorbani P, Wang L, Fullerton MD, Lee SH.

J Biol Chem. 2019 Mar 22;294(12):4644-4655. doi: 10.1074/jbc.RA118.005892. Epub 2019 Jan 29.

PMID:
30696773
6.

Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance.

Loh K, Tam S, Murray-Segal L, Huynh K, Meikle PJ, Scott JW, van Denderen B, Chen Z, Steel R, LeBlond ND, Burkovsky LA, O'Dwyer C, Nunes JRC, Steinberg GR, Fullerton MD, Galic S, Kemp BE.

Hepatol Commun. 2018 Nov 12;3(1):84-98. doi: 10.1002/hep4.1279. eCollection 2019 Jan.

7.

A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling.

van der Veen JN, Lingrell S, McCloskey N, LeBlond ND, Galleguillos D, Zhao YY, Curtis JM, Sipione S, Fullerton MD, Vance DE, Jacobs RL.

FASEB J. 2019 Apr;33(4):5045-5057. doi: 10.1096/fj.201802117R. Epub 2019 Jan 7.

PMID:
30615497
8.

Does prenylation predict progression in NAFLD?

Ghorbani P, Smith TK, Fullerton MD.

J Pathol. 2019 Mar;247(3):283-286. doi: 10.1002/path.5190. Epub 2018 Dec 27.

PMID:
30374976
9.

Choline transport links macrophage phospholipid metabolism and inflammation.

Snider SA, Margison KD, Ghorbani P, LeBlond ND, O'Dwyer C, Nunes JRC, Nguyen T, Xu H, Bennett SAL, Fullerton MD.

J Biol Chem. 2018 Jul 20;293(29):11600-11611. doi: 10.1074/jbc.RA118.003180. Epub 2018 Jun 7.

10.

Methods to Evaluate AMPK Regulation of Macrophage Cholesterol Homeostasis.

LeBlond ND, Fullerton MD.

Methods Mol Biol. 2018;1732:477-493. doi: 10.1007/978-1-4939-7598-3_30.

PMID:
29480494
11.

The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation.

Sundaram M, Curtis KR, Amir Alipour M, LeBlond ND, Margison KD, Yaworski RA, Parks RJ, McIntyre AD, Hegele RA, Fullerton MD, Yao Z.

J Lipid Res. 2017 Nov;58(11):2188-2196. doi: 10.1194/jlr.M077313. Epub 2017 Sep 8.

12.

Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4.

Cavallari JF, Fullerton MD, Duggan BM, Foley KP, Denou E, Smith BK, Desjardins EM, Henriksbo BD, Kim KJ, Tuinema BR, Stearns JC, Prescott D, Rosenstiel P, Coombes BK, Steinberg GR, Schertzer JD.

Cell Metab. 2017 May 2;25(5):1063-1074.e3. doi: 10.1016/j.cmet.2017.03.021. Epub 2017 Apr 20.

13.

Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.

Rollins M, Huard S, Morettin A, Takuski J, Pham TT, Fullerton MD, Côté J, Baetz K.

PLoS Genet. 2017 Feb 23;13(2):e1006626. doi: 10.1371/journal.pgen.1006626. eCollection 2017 Feb.

14.

High intensity interval training improves liver and adipose tissue insulin sensitivity.

Marcinko K, Sikkema SR, Samaan MC, Kemp BE, Fullerton MD, Steinberg GR.

Mol Metab. 2015 Oct 9;4(12):903-15. doi: 10.1016/j.molmet.2015.09.006. eCollection 2015 Dec.

15.

AMP-activated protein kinase and its multifaceted regulation of hepatic metabolism.

Fullerton MD.

Curr Opin Lipidol. 2016 Apr;27(2):172-80. doi: 10.1097/MOL.0000000000000273. Review.

PMID:
26906549
16.

MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis.

Ouimet M, Ediriweera HN, Gundra UM, Sheedy FJ, Ramkhelawon B, Hutchison SB, Rinehold K, van Solingen C, Fullerton MD, Cecchini K, Rayner KJ, Steinberg GR, Zamore PD, Fisher EA, Loke P, Moore KJ.

J Clin Invest. 2015 Oct 26;125(12):4334-48. doi: 10.1172/JCI81676.

17.

Salicylate improves macrophage cholesterol homeostasis via activation of Ampk.

Fullerton MD, Ford RJ, McGregor CP, LeBlond ND, Snider SA, Stypa SA, Day EA, Lhoták Š, Schertzer JD, Austin RC, Kemp BE, Steinberg GR.

J Lipid Res. 2015 May;56(5):1025-33. doi: 10.1194/jlr.M058875. Epub 2015 Mar 15.

18.

Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity.

Ford RJ, Fullerton MD, Pinkosky SL, Day EA, Scott JW, Oakhill JS, Bujak AL, Smith BK, Crane JD, Blümer RM, Marcinko K, Kemp BE, Gerstein HC, Steinberg GR.

Biochem J. 2015 May 15;468(1):125-32. doi: 10.1042/BJ20150125.

19.

Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance.

Denou E, Lolmède K, Garidou L, Pomie C, Chabo C, Lau TC, Fullerton MD, Nigro G, Zakaroff-Girard A, Luche E, Garret C, Serino M, Amar J, Courtney M, Cavallari JF, Henriksbo BD, Barra NG, Foley KP, McPhee JB, Duggan BM, O'Neill HM, Lee AJ, Sansonetti P, Ashkar AA, Khan WI, Surette MG, Bouloumié A, Steinberg GR, Burcelin R, Schertzer JD.

EMBO Mol Med. 2015 Mar;7(3):259-74. doi: 10.15252/emmm.201404169.

20.

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis.

Crane JD, Palanivel R, Mottillo EP, Bujak AL, Wang H, Ford RJ, Collins A, Blümer RM, Fullerton MD, Yabut JM, Kim JJ, Ghia JE, Hamza SM, Morrison KM, Schertzer JD, Dyck JR, Khan WI, Steinberg GR.

Nat Med. 2015 Feb;21(2):166-72. doi: 10.1038/nm.3766. Epub 2014 Dec 8.

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